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The map label for this gene is ribD [H]

Identifier: 218710376

GI number: 218710376

Start: 2582176

End: 2583300

Strand: Reverse

Name: ribD [H]

Synonym: VS_2413

Alternate gene names: 218710376

Gene position: 2583300-2582176 (Counterclockwise)

Preceding gene: 218710377

Following gene: 218710375

Centisome position: 78.3

GC content: 46.93

Gene sequence:

>1125_bases
ATGTCAAACTTTACTCCCCTAGATTTTCAAATGATGTCACGTGCTATTAAGTTAGCCAAACGCGGCATTTACACTACTGC
ACCAAACCCGAATGTGGGTTGTGTCATCGTGCAAACCGATGGCCAGATCGTTGGCGAAGGTTTCCATGCCAAAGCTGGCG
AAGCTCATGCCGAAGTACACGCTATGAGAATGGCGGGTGATAAGGCAAAAGGTGCGATCGCTTATGTCACGCTAGAACCT
TGCTCGCACTATGGTCGAACGCCACCTTGTGCTGAAGGTTTGATTAAGGCTCAAGTAGCCAAAGTGATTTGTGCCATGCA
GGACCCAAACCCAAAAGTTGCAGGTCGTGGTATCAAAATGCTACGCGATGCGTGTATTGAGGTTGAAATCGGTTTATTAG
AGCAAGATGCTCTCGACTTGAACCCTGCATTTATCAAGCGTATGCAAACGGGCATGCCATTCGTTCAGTTAAAGATGGCC
GCTAGCCTTGATGGGCAAACGGCATTGGAAAATGGTCAAAGCCAGTGGATCACATCGCCAGAAGCGCGTCGTGATGTTCA
GAACTACCGAGCAAAATCAGGCGCTGTGCTATCAACCAGCCAGACGGTGATTGAAGACAACGCGTCGTTGAATGTTCGCT
GGACTGAGTTACCAAGCAGTATCAAAGAGCATTACGCTGAAGACGAGCTGCGTCAGCCAATTCGCGTAATTCTTGATCGC
CAAAATCAACTGTATCCTGAGCTCAAGTTATTCCAAACTCCAACATCGGTATTGAGAGTCGCTGAAACCTCTGCTGATAT
TGAAGTCGAAACCACAGATGCAGGTCAGCTCGATTTACACGATCTAATGCGTCAATTGCCAGCGAACCATATTGATCATA
TTTGGGTCGAAGCGGGCGCTACCTTGGCAAAAAGCTTGATTGAAGCGCAGCTAGTGGATGAGCTAATCCTTTATTTAGCA
CCTAAACTAATGGGCAGTGACGGACGAGGTTTGATGGGCGCATTAGGACTCACTTCAATGTCTGATGTGATTGACCTAGA
AATTAAAGATGTTCGACAGGTTGGTGTGGATATTCGCATCGTCGCGAAACCTATTATCGCGAAACAAATAATAACGAAAC
CATAG

Upstream 100 bases:

>100_bases
AAAGTGGCGTACATTCGTTTTGCCTCTGTTTACCGCAGCTTTGAAGACATCCGAGAGTTTGGCGAAGAAATCGCTAAATT
AGAGGATTAACTCCTCAATC

Downstream 100 bases:

>100_bases
TGGAAATAGTTCTGCTAACCAAATACATGTCGTTGACAACAAAAAGAGTTTTAAAATGTTTACAGGAATTGTAGAAGCCG
TAGGTACATTGAGTGCAATC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MSNFTPLDFQMMSRAIKLAKRGIYTTAPNPNVGCVIVQTDGQIVGEGFHAKAGEAHAEVHAMRMAGDKAKGAIAYVTLEP
CSHYGRTPPCAEGLIKAQVAKVICAMQDPNPKVAGRGIKMLRDACIEVEIGLLEQDALDLNPAFIKRMQTGMPFVQLKMA
ASLDGQTALENGQSQWITSPEARRDVQNYRAKSGAVLSTSQTVIEDNASLNVRWTELPSSIKEHYAEDELRQPIRVILDR
QNQLYPELKLFQTPTSVLRVAETSADIEVETTDAGQLDLHDLMRQLPANHIDHIWVEAGATLAKSLIEAQLVDELILYLA
PKLMGSDGRGLMGALGLTSMSDVIDLEIKDVRQVGVDIRIVAKPIIAKQIITKP

Sequences:

>Translated_374_residues
MSNFTPLDFQMMSRAIKLAKRGIYTTAPNPNVGCVIVQTDGQIVGEGFHAKAGEAHAEVHAMRMAGDKAKGAIAYVTLEP
CSHYGRTPPCAEGLIKAQVAKVICAMQDPNPKVAGRGIKMLRDACIEVEIGLLEQDALDLNPAFIKRMQTGMPFVQLKMA
ASLDGQTALENGQSQWITSPEARRDVQNYRAKSGAVLSTSQTVIEDNASLNVRWTELPSSIKEHYAEDELRQPIRVILDR
QNQLYPELKLFQTPTSVLRVAETSADIEVETTDAGQLDLHDLMRQLPANHIDHIWVEAGATLAKSLIEAQLVDELILYLA
PKLMGSDGRGLMGALGLTSMSDVIDLEIKDVRQVGVDIRIVAKPIIAKQIITKP
>Mature_373_residues
SNFTPLDFQMMSRAIKLAKRGIYTTAPNPNVGCVIVQTDGQIVGEGFHAKAGEAHAEVHAMRMAGDKAKGAIAYVTLEPC
SHYGRTPPCAEGLIKAQVAKVICAMQDPNPKVAGRGIKMLRDACIEVEIGLLEQDALDLNPAFIKRMQTGMPFVQLKMAA
SLDGQTALENGQSQWITSPEARRDVQNYRAKSGAVLSTSQTVIEDNASLNVRWTELPSSIKEHYAEDELRQPIRVILDRQ
NQLYPELKLFQTPTSVLRVAETSADIEVETTDAGQLDLHDLMRQLPANHIDHIWVEAGATLAKSLIEAQLVDELILYLAP
KLMGSDGRGLMGALGLTSMSDVIDLEIKDVRQVGVDIRIVAKPIIAKQIITKP

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=359, Percent_Identity=55.4317548746518, Blast_Score=397, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40911; Mature: 40780

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFTPLDFQMMSRAIKLAKRGIYTTAPNPNVGCVIVQTDGQIVGEGFHAKAGEAHAEVH
CCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCEEEEECCCEEECCCCCCCCCCHHHHHH
AMRMAGDKAKGAIAYVTLEPCSHYGRTPPCAEGLIKAQVAKVICAMQDPNPKVAGRGIKM
HHHHCCCCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHH
LRDACIEVEIGLLEQDALDLNPAFIKRMQTGMPFVQLKMAASLDGQTALENGQSQWITSP
HHHHHHEEEECEECCCCCCCCHHHHHHHHCCCCEEEEEEHHCCCCHHHHHCCCCCCCCCC
EARRDVQNYRAKSGAVLSTSQTVIEDNASLNVRWTELPSSIKEHYAEDELRQPIRVILDR
HHHHHHHHHHHCCCCEEECCCCEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
QNQLYPELKLFQTPTSVLRVAETSADIEVETTDAGQLDLHDLMRQLPANHIDHIWVEAGA
CCCCCCCHHHHCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCHHCEEHHHHHH
TLAKSLIEAQLVDELILYLAPKLMGSDGRGLMGALGLTSMSDVIDLEIKDVRQVGVDIRI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCEEE
VAKPIIAKQIITKP
EHHHHHHHHHHCCC
>Mature Secondary Structure 
SNFTPLDFQMMSRAIKLAKRGIYTTAPNPNVGCVIVQTDGQIVGEGFHAKAGEAHAEVH
CCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCEEEEECCCEEECCCCCCCCCCHHHHHH
AMRMAGDKAKGAIAYVTLEPCSHYGRTPPCAEGLIKAQVAKVICAMQDPNPKVAGRGIKM
HHHHCCCCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHH
LRDACIEVEIGLLEQDALDLNPAFIKRMQTGMPFVQLKMAASLDGQTALENGQSQWITSP
HHHHHHEEEECEECCCCCCCCHHHHHHHHCCCCEEEEEEHHCCCCHHHHHCCCCCCCCCC
EARRDVQNYRAKSGAVLSTSQTVIEDNASLNVRWTELPSSIKEHYAEDELRQPIRVILDR
HHHHHHHHHHHCCCCEEECCCCEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
QNQLYPELKLFQTPTSVLRVAETSADIEVETTDAGQLDLHDLMRQLPANHIDHIWVEAGA
CCCCCCCHHHHCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCHHCEEHHHHHH
TLAKSLIEAQLVDELILYLAPKLMGSDGRGLMGALGLTSMSDVIDLEIKDVRQVGVDIRI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCEEE
VAKPIIAKQIITKP
EHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]