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The map label for this gene is mukE [H]

Identifier: 218709089

GI number: 218709089

Start: 1152647

End: 1153453

Strand: Direct

Name: mukE [H]

Synonym: VS_1095

Alternate gene names: 218709089

Gene position: 1152647-1153453 (Clockwise)

Preceding gene: 218709088

Following gene: 218709090

Centisome position: 34.94

GC content: 43.25

Gene sequence:

>807_bases
ATGTCATTAACAAGTACTGATGATTACATGCCAGAGAAACTGGTAAAAGCGATAGCGAACCCATTGTTTCCTGCGCTAGA
TAGCATGTTGCGTTCAGGCAAGCATGTTTCAACAGAAGACCTCGATAACCATGCGTTGCTTTCTGATTTTGAAGTTGAGC
TTCAGCATTTTTATCAACGCTACAATACGGAACTGGTAAAAGCGCCTGAAGGTTTCTTCTATCTGCGCCCGCGTTCTACG
TCTTTAATTGGTCGTAGTGTGTTGTCTGAGCTCGACATGCTGGTTGGCAAAGTATTGTGTTTCTTATACCTAAGCCCAGA
GCGTTTGGCTCATGAAGGCATCTTCACCAATCAAGAGTTGTTTGATGAACTGATGTCGTTAGCGGATGAGAAAAAACTCA
TGAAGCTAGCAACCAACCGTGCGTCTGGTTCTGACTTAGACAAAGAAAAGCTGTTTGAAAAAGTACGTACTTCTTTACGC
CGTTTACGTCGTATCGGCATGCTGATCGTGATTGGTGAAACAGGTAAATTCCGTATCAGCGAAGCGGTGTTCCGTTTTGG
TGCGGATGTTCGTGTTGGCGATGATATGAAAGAAGCGCAATTACGACTTATTCGTGATGGTGAAGCTGTTGTTCATACTC
AAGAACCTAACCAAGGTAGCTTGTTGAATGAAGAACAAGCAGAAGCCGTATCAGAAATAGATTTAGACGTAGACGAAAAC
GGTCAACAAGATATTTTTAACGATCAAGCCGGCTTTGACCTTGAGTCAAGCGATGGCGAACAAACAAAAGTAGAAGGTGA
AGCATGA

Upstream 100 bases:

>100_bases
GTCGACCAAGCCGTTCGCTTAGGTTACTCAGAGTCTGACTATCAGGCTATTCAGCCAGATTGGCAGGCAATCAACGATTT
CGGTGCAAAGGTACAAGCAA

Downstream 100 bases:

>100_bases
TTGAAAGAGGTAAGTATCAATCATTAACCATGATCAACTGGAACGGTTTCTTTGCACGTACTTTTGATATCGATGGATTG
GTTACAACGCTTTCTGGCGG

Product: condesin subunit E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSLTSTDDYMPEKLVKAIANPLFPALDSMLRSGKHVSTEDLDNHALLSDFEVELQHFYQRYNTELVKAPEGFFYLRPRST
SLIGRSVLSELDMLVGKVLCFLYLSPERLAHEGIFTNQELFDELMSLADEKKLMKLATNRASGSDLDKEKLFEKVRTSLR
RLRRIGMLIVIGETGKFRISEAVFRFGADVRVGDDMKEAQLRLIRDGEAVVHTQEPNQGSLLNEEQAEAVSEIDLDVDEN
GQQDIFNDQAGFDLESSDGEQTKVEGEA

Sequences:

>Translated_268_residues
MSLTSTDDYMPEKLVKAIANPLFPALDSMLRSGKHVSTEDLDNHALLSDFEVELQHFYQRYNTELVKAPEGFFYLRPRST
SLIGRSVLSELDMLVGKVLCFLYLSPERLAHEGIFTNQELFDELMSLADEKKLMKLATNRASGSDLDKEKLFEKVRTSLR
RLRRIGMLIVIGETGKFRISEAVFRFGADVRVGDDMKEAQLRLIRDGEAVVHTQEPNQGSLLNEEQAEAVSEIDLDVDEN
GQQDIFNDQAGFDLESSDGEQTKVEGEA
>Mature_267_residues
SLTSTDDYMPEKLVKAIANPLFPALDSMLRSGKHVSTEDLDNHALLSDFEVELQHFYQRYNTELVKAPEGFFYLRPRSTS
LIGRSVLSELDMLVGKVLCFLYLSPERLAHEGIFTNQELFDELMSLADEKKLMKLATNRASGSDLDKEKLFEKVRTSLRR
LRRIGMLIVIGETGKFRISEAVFRFGADVRVGDDMKEAQLRLIRDGEAVVHTQEPNQGSLLNEEQAEAVSEIDLDVDENG
QQDIFNDQAGFDLESSDGEQTKVEGEA

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interactio

COG id: COG3095

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukE family [H]

Homologues:

Organism=Escherichia coli, GI226510932, Length=211, Percent_Identity=68.7203791469194, Blast_Score=308, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007385 [H]

Pfam domain/function: PF04288 MukE [H]

EC number: NA

Molecular weight: Translated: 30256; Mature: 30124

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTSTDDYMPEKLVKAIANPLFPALDSMLRSGKHVSTEDLDNHALLSDFEVELQHFYQR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
YNTELVKAPEGFFYLRPRSTSLIGRSVLSELDMLVGKVLCFLYLSPERLAHEGIFTNQEL
HCCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHH
FDELMSLADEKKLMKLATNRASGSDLDKEKLFEKVRTSLRRLRRIGMLIVIGETGKFRIS
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHH
EAVFRFGADVRVGDDMKEAQLRLIRDGEAVVHTQEPNQGSLLNEEQAEAVSEIDLDVDEN
HHHHHHCCCCEECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCC
GQQDIFNDQAGFDLESSDGEQTKVEGEA
CCHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLTSTDDYMPEKLVKAIANPLFPALDSMLRSGKHVSTEDLDNHALLSDFEVELQHFYQR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
YNTELVKAPEGFFYLRPRSTSLIGRSVLSELDMLVGKVLCFLYLSPERLAHEGIFTNQEL
HCCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHH
FDELMSLADEKKLMKLATNRASGSDLDKEKLFEKVRTSLRRLRRIGMLIVIGETGKFRIS
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHH
EAVFRFGADVRVGDDMKEAQLRLIRDGEAVVHTQEPNQGSLLNEEQAEAVSEIDLDVDEN
HHHHHHCCCCEECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCC
GQQDIFNDQAGFDLESSDGEQTKVEGEA
CCHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]