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The map label for this gene is nqrD [H]

Identifier: 218708717

GI number: 218708717

Start: 730471

End: 731103

Strand: Direct

Name: nqrD [H]

Synonym: VS_0696

Alternate gene names: 218708717

Gene position: 730471-731103 (Clockwise)

Preceding gene: 218708716

Following gene: 218708718

Centisome position: 22.14

GC content: 43.6

Gene sequence:

>633_bases
ATGTCTAGTGCAAAAGAAATTAAAAAGAGCATCTTAGCGCCGGTGTTGGACAACAACCCAATCGCGCTACAGGTTCTTGG
TGTGTGTTCTGCTCTTGCGGTAACCACTAAACTAGAAACAGCGTTTGTTATGACTATCGCGGTAATGTTCGTTACTGCTC
TGTCTAACTTCTTCGTTTCTTTGATCCGTAACCACATTCCGAACAGTGTGCGTATCATCGTTCAGATGGCAATTATCGCA
TCATTAGTAATCGTGGTAGACCAAGTGCTTAAAGCATACCTATACGATATCTCTAAGCAGCTATCTGTATTCGTTGGCCT
AATCATTACTAACTGTATTGTAATGGGCCGTGCTGAAGCATTCGCAATGAAGTCTGCACCAATCCCATCTTTCATCGATG
GCCTTGGTAACGGTCTTGGTTACGGTTTCGTATTGATCACTGTTGGTTTCTTCCGTGAGCTTCTTGGCTCTGGCAAACTA
TTTGATATGGAAGTACTACCTCTAGTGAGCAACGGTGGTTGGTATCAGCCAAACGGCTTGATGCTTCTAGCACCTTCAGC
ATTCTTCCTAATTGGTTTCTTGATTTGGGCAATTCGTGTGTTCAAACCAGAACAAGTAGAAGCGAAGGGGTAA

Upstream 100 bases:

>100_bases
CACTAACAAGTGTTGGTGTTCAACATACATTTGACTTCTGGTTAGGTGATATGGGCTTTGGTCCGTTCCTAGCAAAAGTT
CGTGACGGAGGTCTGAACTA

Downstream 100 bases:

>100_bases
GGTAGTCATGGAACATTATATTAGTCTGCTAGTTAAATCGATTTTCATCGAAAACATGGCGCTTTCTTTCTTCCTAGGTA
TGTGTACATTCCTAGCGGTT

Product: Na(+)-translocating NADH-quinone reductase subunit D

Products: NA

Alternate protein names: Na(+)-NQR subunit D; Na(+)-translocating NQR subunit D; NQR complex subunit D; NQR-1 subunit D [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MSSAKEIKKSILAPVLDNNPIALQVLGVCSALAVTTKLETAFVMTIAVMFVTALSNFFVSLIRNHIPNSVRIIVQMAIIA
SLVIVVDQVLKAYLYDISKQLSVFVGLIITNCIVMGRAEAFAMKSAPIPSFIDGLGNGLGYGFVLITVGFFRELLGSGKL
FDMEVLPLVSNGGWYQPNGLMLLAPSAFFLIGFLIWAIRVFKPEQVEAKG

Sequences:

>Translated_210_residues
MSSAKEIKKSILAPVLDNNPIALQVLGVCSALAVTTKLETAFVMTIAVMFVTALSNFFVSLIRNHIPNSVRIIVQMAIIA
SLVIVVDQVLKAYLYDISKQLSVFVGLIITNCIVMGRAEAFAMKSAPIPSFIDGLGNGLGYGFVLITVGFFRELLGSGKL
FDMEVLPLVSNGGWYQPNGLMLLAPSAFFLIGFLIWAIRVFKPEQVEAKG
>Mature_209_residues
SSAKEIKKSILAPVLDNNPIALQVLGVCSALAVTTKLETAFVMTIAVMFVTALSNFFVSLIRNHIPNSVRIIVQMAIIAS
LVIVVDQVLKAYLYDISKQLSVFVGLIITNCIVMGRAEAFAMKSAPIPSFIDGLGNGLGYGFVLITVGFFRELLGSGKLF
DMEVLPLVSNGGWYQPNGLMLLAPSAFFLIGFLIWAIRVFKPEQVEAKG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1347

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrDE/rnfAE family [H]

Homologues:

Organism=Escherichia coli, GI1787919, Length=202, Percent_Identity=36.1386138613861, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003667
- InterPro:   IPR011292 [H]

Pfam domain/function: PF02508 Rnf-Nqr [H]

EC number: NA

Molecular weight: Translated: 22732; Mature: 22600

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAKEIKKSILAPVLDNNPIALQVLGVCSALAVTTKLETAFVMTIAVMFVTALSNFFVS
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIRNHIPNSVRIIVQMAIIASLVIVVDQVLKAYLYDISKQLSVFVGLIITNCIVMGRAEA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
FAMKSAPIPSFIDGLGNGLGYGFVLITVGFFRELLGSGKLFDMEVLPLVSNGGWYQPNGL
HHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEECCCCE
MLLAPSAFFLIGFLIWAIRVFKPEQVEAKG
EEECCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SSAKEIKKSILAPVLDNNPIALQVLGVCSALAVTTKLETAFVMTIAVMFVTALSNFFVS
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIRNHIPNSVRIIVQMAIIASLVIVVDQVLKAYLYDISKQLSVFVGLIITNCIVMGRAEA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
FAMKSAPIPSFIDGLGNGLGYGFVLITVGFFRELLGSGKLFDMEVLPLVSNGGWYQPNGL
HHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEECCCCE
MLLAPSAFFLIGFLIWAIRVFKPEQVEAKG
EEECCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7805867; 7729558; 9490015; 10549856; 11248187; 11248188 [H]