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The map label for this gene is argA

Identifier: 218708699

GI number: 218708699

Start: 712296

End: 713633

Strand: Reverse

Name: argA

Synonym: VS_0678

Alternate gene names: 218708699

Gene position: 713633-712296 (Counterclockwise)

Preceding gene: 218708704

Following gene: 218708698

Centisome position: 21.63

GC content: 46.94

Gene sequence:

>1338_bases
GTGAAATTAAGAAGTACGGCGCTAGTCAAAGGCTTTAGGCAATCGACCCCTTATGTAAATGCTCACCGTGGTAAAACCAT
GGTGATTATGTTGGGGGGTGAAGCCGTTGCCGATAGAAACTTTGGCAACATTATTAGTGATATAGCCCTGCTTCATAGCC
TTGGGGTTAAGATTGTTCTCGTTCATGGGGCAAGACCACAGATCAACCAACTGTTAGAGAAGCAAGACTGCCATACGCCT
TACCATAAAAATATTAGAGTCACAGATGAATATTCTTTAGGTGTTGCAATGCAGGCGGCTGGACAACTGCAACTTGCGAT
CACCGCTCGTCTTTCAATGAGTTTGAACAACACCCCAATGGCAGGAACTCAACTCAATGTTATGAGTGGTAACTTCATTA
CCGCTCAACCCTTAGGCGTCGATGATGGTACAGATTACTGCCACAGTGGACGCATTCGTCGAATAGACATCGAAGGGATC
AATCGCACCCTTGACCAAGGTTCCATCGTCCTTCTTGGGCCGATTGCCAGTTCAGTCACTGGCGAAAGCTTTAACCTGCT
TTCGGAAGAGGTCGCGACACAAGTTGCTATCCGTTTGAAAGCCGACAAACTGATTGGCTTTTGTTCTGAGCAAGGGGTGA
CTGACGAAAGCGGTAATGTACTAGCCGAACTCTTCCCTAAAGACGCCAAGCAAATTCTTGAACGCTTAACGGAATCCCAG
AACCCCGCCGAAGACATGAGCACCGGAACACTGCGCTTCTTGAAAGGAGCGATCTCCGCTTGCCGAGCAGGCGTGCCTCG
TTGTCACTTGATCAGCTACAAAGTCGATGGCGCATTGATCCAAGAGCTATTCTCTTTTGATGGTATTGGAACCCAAGTGG
TCATGGCGAGTGCCGAACAAGTCAGACAAGCTCAGATTGATGACATCGGTGGTATCTTTGACCTCATTCGTCCTCTTGAA
GAACAAGGCATTCTTGTTCGTCGCTCAAGAGAGCAGTTAGAACAAGAAGTCCATCGTTTTACCATCATCGAAAAAGACGG
TCTGATCATTGGTTGCGCTGCGCTATACGCTTATCCAGAAGATCACATGGCAGAGATGGCCTGTGTGGCCATTCACCCAG
ACTACCGAGATGGCAACCGTGGGCAGATACTGCTGGATTACATGCGTCATCAGTCCAAATCTCGTGATATCGACCAGATC
TTTGTTCTTACCACACACAGCCTTCATTGGTTTCGTGAACAGGGTTTTTACGAGATTGCTGTTGATGAATTACCAATGGA
AAAGCAAGGTCTGTACAACTATCAAAGAAATTCCAAGATCTTAGCGTTAAATGTGTAA

Upstream 100 bases:

>100_bases
CCTAGATGAGAATAGTTTGCGCTTCATTCCAAAAAGTTGTTGTTCAGATTTGAATTTAAATGCTAAATTATCGAATAAAT
AAACAAGCAAGGCTTATTCT

Downstream 100 bases:

>100_bases
ACTAAATTTGGAGTAAAATCTCACTTTAACAAGGAATCTATTGCAAATGCAATCGTTTCTCATGTGAGATTTATTAAATA
TGCACTTTCATTCACAGCTA

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKLRSTALVKGFRQSTPYVNAHRGKTMVIMLGGEAVADRNFGNIISDIALLHSLGVKIVLVHGARPQINQLLEKQDCHTP
YHKNIRVTDEYSLGVAMQAAGQLQLAITARLSMSLNNTPMAGTQLNVMSGNFITAQPLGVDDGTDYCHSGRIRRIDIEGI
NRTLDQGSIVLLGPIASSVTGESFNLLSEEVATQVAIRLKADKLIGFCSEQGVTDESGNVLAELFPKDAKQILERLTESQ
NPAEDMSTGTLRFLKGAISACRAGVPRCHLISYKVDGALIQELFSFDGIGTQVVMASAEQVRQAQIDDIGGIFDLIRPLE
EQGILVRRSREQLEQEVHRFTIIEKDGLIIGCAALYAYPEDHMAEMACVAIHPDYRDGNRGQILLDYMRHQSKSRDIDQI
FVLTTHSLHWFREQGFYEIAVDELPMEKQGLYNYQRNSKILALNV

Sequences:

>Translated_445_residues
MKLRSTALVKGFRQSTPYVNAHRGKTMVIMLGGEAVADRNFGNIISDIALLHSLGVKIVLVHGARPQINQLLEKQDCHTP
YHKNIRVTDEYSLGVAMQAAGQLQLAITARLSMSLNNTPMAGTQLNVMSGNFITAQPLGVDDGTDYCHSGRIRRIDIEGI
NRTLDQGSIVLLGPIASSVTGESFNLLSEEVATQVAIRLKADKLIGFCSEQGVTDESGNVLAELFPKDAKQILERLTESQ
NPAEDMSTGTLRFLKGAISACRAGVPRCHLISYKVDGALIQELFSFDGIGTQVVMASAEQVRQAQIDDIGGIFDLIRPLE
EQGILVRRSREQLEQEVHRFTIIEKDGLIIGCAALYAYPEDHMAEMACVAIHPDYRDGNRGQILLDYMRHQSKSRDIDQI
FVLTTHSLHWFREQGFYEIAVDELPMEKQGLYNYQRNSKILALNV
>Mature_445_residues
MKLRSTALVKGFRQSTPYVNAHRGKTMVIMLGGEAVADRNFGNIISDIALLHSLGVKIVLVHGARPQINQLLEKQDCHTP
YHKNIRVTDEYSLGVAMQAAGQLQLAITARLSMSLNNTPMAGTQLNVMSGNFITAQPLGVDDGTDYCHSGRIRRIDIEGI
NRTLDQGSIVLLGPIASSVTGESFNLLSEEVATQVAIRLKADKLIGFCSEQGVTDESGNVLAELFPKDAKQILERLTESQ
NPAEDMSTGTLRFLKGAISACRAGVPRCHLISYKVDGALIQELFSFDGIGTQVVMASAEQVRQAQIDDIGGIFDLIRPLE
EQGILVRRSREQLEQEVHRFTIIEKDGLIIGCAALYAYPEDHMAEMACVAIHPDYRDGNRGQILLDYMRHQSKSRDIDQI
FVLTTHSLHWFREQGFYEIAVDELPMEKQGLYNYQRNSKILALNV

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain

Homologues:

Organism=Escherichia coli, GI1789181, Length=441, Percent_Identity=62.8117913832199, Blast_Score=593, Evalue=1e-171,
Organism=Saccharomyces cerevisiae, GI6320913, Length=190, Percent_Identity=24.7368421052632, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGA_VIBSL (B7VJZ6)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002416320.1
- ProteinModelPortal:   B7VJZ6
- GeneID:   7160297
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0678
- HOGENOM:   HBG545264
- OMA:   APYIHAF
- ProtClustDB:   PRK05279
- GO:   GO:0005737
- HAMAP:   MF_01105
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167
- Gene3D:   G3DSA:3.40.1160.10
- Gene3D:   G3DSA:3.40.630.30
- PIRSF:   PIRSF000423
- TIGRFAMs:   TIGR01890

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1; SSF53633 Aa_kinase; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.1.1

Molecular weight: Translated: 49310; Mature: 49310

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS51186 GNAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRSTALVKGFRQSTPYVNAHRGKTMVIMLGGEAVADRNFGNIISDIALLHSLGVKIVL
CCCCHHHHHHHHHHCCCEEEECCCCEEEEEECCCEECCCCHHHHHHHHHHHHHCCEEEEE
VHGARPQINQLLEKQDCHTPYHKNIRVTDEYSLGVAMQAAGQLQLAITARLSMSLNNTPM
EECCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCEEEEEEEEEEEEECCCCC
AGTQLNVMSGNFITAQPLGVDDGTDYCHSGRIRRIDIEGINRTLDQGSIVLLGPIASSVT
CCCEEEEEECCEEEECCCCCCCCCCHHHCCCEEEEECCCCCHHCCCCCEEEEECCCCCCC
GESFNLLSEEVATQVAIRLKADKLIGFCSEQGVTDESGNVLAELFPKDAKQILERLTESQ
CCHHHHHHHHHHHHHHEEEEHHHHHEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCC
NPAEDMSTGTLRFLKGAISACRAGVPRCHLISYKVDGALIQELFSFDGIGTQVVMASAEQ
CCHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHH
VRQAQIDDIGGIFDLIRPLEEQGILVRRSREQLEQEVHRFTIIEKDGLIIGCAALYAYPE
HHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHEEEEECCCCEEEEHHHHCCCH
DHMAEMACVAIHPDYRDGNRGQILLDYMRHQSKSRDIDQIFVLTTHSLHWFREQGFYEIA
HHHHCEEEEEECCCCCCCCCCCEEHHHHHCCCCCCCCEEEEEEEECCHHHHHHCCCEEEE
VDELPMEKQGLYNYQRNSKILALNV
ECCCCCCHHCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKLRSTALVKGFRQSTPYVNAHRGKTMVIMLGGEAVADRNFGNIISDIALLHSLGVKIVL
CCCCHHHHHHHHHHCCCEEEECCCCEEEEEECCCEECCCCHHHHHHHHHHHHHCCEEEEE
VHGARPQINQLLEKQDCHTPYHKNIRVTDEYSLGVAMQAAGQLQLAITARLSMSLNNTPM
EECCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCEEEEEEEEEEEEECCCCC
AGTQLNVMSGNFITAQPLGVDDGTDYCHSGRIRRIDIEGINRTLDQGSIVLLGPIASSVT
CCCEEEEEECCEEEECCCCCCCCCCHHHCCCEEEEECCCCCHHCCCCCEEEEECCCCCCC
GESFNLLSEEVATQVAIRLKADKLIGFCSEQGVTDESGNVLAELFPKDAKQILERLTESQ
CCHHHHHHHHHHHHHHEEEEHHHHHEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCC
NPAEDMSTGTLRFLKGAISACRAGVPRCHLISYKVDGALIQELFSFDGIGTQVVMASAEQ
CCHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHH
VRQAQIDDIGGIFDLIRPLEEQGILVRRSREQLEQEVHRFTIIEKDGLIIGCAALYAYPE
HHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHEEEEECCCCEEEEHHHHCCCH
DHMAEMACVAIHPDYRDGNRGQILLDYMRHQSKSRDIDQIFVLTTHSLHWFREQGFYEIA
HHHHCEEEEEECCCCCCCCCCCEEHHHHHCCCCCCCCEEEEEEEECCHHHHHHCCCEEEE
VDELPMEKQGLYNYQRNSKILALNV
ECCCCCCHHCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA