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The map label for this gene is betI [H]

Identifier: 218703597

GI number: 218703597

Start: 381882

End: 382469

Strand: Reverse

Name: betI [H]

Synonym: ECUMN_0351

Alternate gene names: 218703597

Gene position: 382469-381882 (Counterclockwise)

Preceding gene: 218703599

Following gene: 218703596

Centisome position: 7.35

GC content: 55.27

Gene sequence:

>588_bases
ATGCCCAAATTGGGGATGCAGTCGATCCGGCGCAGACAACTGATCGACGCCACGCTGGAAGCAATAAATGAAGTGGGCAT
GCACGATGCAACGATCGCGCAGATCGCCCGCCGTGCAGGCGTTTCTACGGGGATCATCAGCCACTATTTCAGGGACAAAA
ATGGTCTGCTGGAAGCAACCATGCGCGATATCACCAGTCAGCTGCGTGACGCGGTTTTGAATCGATTACATGCACTTCCG
CAGGGCAGTGCAGAGCAGCGATTACAGGCGATTGTTGACGGGAATTTCGATGAAACGCAGGTCAGTAATGCTGCGATGAA
AGCCTGGTTGGCGTTTTGGGCCAGCAGTATGCATCAGCCAATGCTTTACCGTTTGCAGCAGGTGAGCAGCCGCCGCTTGT
TGTCGAATCTGGTGAGCGAATTTCACCGCGAGTTACCGCGCCAACAGGCACAGGAAGCGGGCTACGGCCTTGCCGCGCTG
ATTGACGGATTATGGCTGCGCGCGGCACTGAGCGGCAAACCGCTGGATAAACCTCTCGCACACTCGCTGACCCGTCACTT
TATTACTCAGCATTTACCCACCGATTAA

Upstream 100 bases:

>100_bases
TTAAAATCAAATTCGTAACAATTAAGACACATTTTATATTGAACGTCCAATCAATAACCGCTTTAATAGATAAACAACGC
TGATGAATGGAGTGGCGAAA

Downstream 100 bases:

>100_bases
CCGAGGAGACGTGATGTCCCGAATGGCAGAACAGCAGCTTTATATACATGGTGGTTATACCTCCGCCACCAGCGGTCGCA
CCTTCGAGACCATTAACCCG

Product: transcriptional regulator BetI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALP
QGSAEQRLQAIVDGNFDETQVSNAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFHRELPRQQAQEAGYGLAAL
IDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD

Sequences:

>Translated_195_residues
MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALP
QGSAEQRLQAIVDGNFDETQVSNAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFHRELPRQQAQEAGYGLAAL
IDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD
>Mature_194_residues
PKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQ
GSAEQRLQAIVDGNFDETQVSNAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFHRELPRQQAQEAGYGLAALI
DGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD

Specific function: Repressor involved in choline regulation of the bet genes [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786505, Length=195, Percent_Identity=96.4102564102564, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR017757
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21856; Mature: 21725

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEAT
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHH
MRDITSQLRDAVLNRLHALPQGSAEQRLQAIVDGNFDETQVSNAAMKAWLAFWASSMHQP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCH
MLYRLQQVSSRRLLSNLVSEFHRELPRQQAQEAGYGLAALIDGLWLRAALSGKPLDKPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHH
HSLTRHFITQHLPTD
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
PKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEAT
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHH
MRDITSQLRDAVLNRLHALPQGSAEQRLQAIVDGNFDETQVSNAAMKAWLAFWASSMHQP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCH
MLYRLQQVSSRRLLSNLVSEFHRELPRQQAQEAGYGLAALIDGLWLRAALSGKPLDKPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHH
HSLTRHFITQHLPTD
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA