Click here to switch to the map view.

The map label for this gene is yfcH

Identifier: 218700778

GI number: 218700778

Start: 2538993

End: 2539886

Strand: Direct

Name: yfcH

Synonym: ECIAI39_2451

Alternate gene names: 218700778

Gene position: 2538993-2539886 (Clockwise)

Preceding gene: 218700777

Following gene: 218700797

Centisome position: 49.47

GC content: 54.36

Gene sequence:

>894_bases
ATGAAGATAGTGATCACCGGAGGGACGGGATTAATTGGTCGCCATTTGATTCCGCGTTTGCTGGATCTGGGCCATCAAAT
CACGGTAGTGACGCGTAACCCGCAGAAAGCCAGTTCCGTTCTCGGCCCTCGGGTGACACTATGGCAAGGGCTTGCCGATC
AAAGTAACCTCAACGGCGTTGATGCGGTAATCAACCTGGCCGGAGAGCCGATTGCTGATAAACGCTGGACTCACGAGCAA
AAAGAGCGTCTCTGCCAAAGCCGCTGGAATATCACGCAAAAACTGGTCGATTTGATTAATGCCAGCGACACGCCACCGTC
GGTACTCATTTCCGGCTCGGCAACGGGCTATTATGGCGACTTAGGTGAAGTGGTGGTTACCGAAGAGGAACCGCCGCATA
ACGAATTTACTCATAAACTCTGCGCCCGCTGGGAAGAAATTGCCTGTCGGGCACAAAGTGACAAAACGCGAGTGTGCCTG
CTGCGTACCGGCGTAGTGCTGGCACCTGATGGCGGTATTCTCGGTAAAATGCTGCCGCCGTTTCGTCTTGGCCTGGGCGG
GCCGATTGGTTCCGGTCGGCAGTATCTGGCCTGGATTCATATTGATGATATGGTCAATGGCATTCTCTGGCTGCTGGAGA
ACGAGCTGCGCGGGCCATTTAATATGGTTTCGCCCTACCCGGTACGCAATGAACAATTTGCCCATGCGCTCGGTCATGCG
CTGCATCGCCCGGCCATTTTGCGCGTCCCCGCGACCGCTATTCGACTGTTAATGAGCGAATCTTCAGTACTGGTATTAGG
TGGACAACGCGCGCTGCCTAAACGGCTGGAAGAAGCGGGTTTTGCGTTTCGCTGGTACGATTTAGAAGAGGCGCTGGAAA
ACGTAGTCCAGTAA

Upstream 100 bases:

>100_bases
ATGCTGAAGTGGAGATCGATAAACTGCACGCGCTGCGCTACGCCGATTCGGTATCCATGACCTTAAGCTGGCAGCGTTAA
CCGCCATATCGGGAGGCTGC

Downstream 100 bases:

>100_bases
TTTTTTACGTTCTTTCATGCCTGGCAATTATTGCCAGGCATGAAAGCGAGTTATTTACCTTTATCTACGAGCTACTTCGG
GCGCGGCATAGCGAGTGCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKIVITGGTGLIGRHLIPRLLDLGHQITVVTRNPQKASSVLGPRVTLWQGLADQSNLNGVDAVINLAGEPIADKRWTHEQ
KERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLENELRGPFNMVSPYPVRNEQFAHALGHA
LHRPAILRVPATAIRLLMSESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALENVVQ

Sequences:

>Translated_297_residues
MKIVITGGTGLIGRHLIPRLLDLGHQITVVTRNPQKASSVLGPRVTLWQGLADQSNLNGVDAVINLAGEPIADKRWTHEQ
KERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLENELRGPFNMVSPYPVRNEQFAHALGHA
LHRPAILRVPATAIRLLMSESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALENVVQ
>Mature_297_residues
MKIVITGGTGLIGRHLIPRLLDLGHQITVVTRNPQKASSVLGPRVTLWQGLADQSNLNGVDAVINLAGEPIADKRWTHEQ
KERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLENELRGPFNMVSPYPVRNEQFAHALGHA
LHRPAILRVPATAIRLLMSESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALENVVQ

Specific function: Unknown

COG id: COG1090

COG function: function code R; Predicted nucleoside-diphosphate sugar epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. SDR39U1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI116812630, Length=301, Percent_Identity=36.2126245847176, Blast_Score=179, Evalue=3e-45,
Organism=Escherichia coli, GI1788642, Length=297, Percent_Identity=97.6430976430976, Blast_Score=593, Evalue=1e-171,
Organism=Drosophila melanogaster, GI28573846, Length=292, Percent_Identity=30.8219178082192, Blast_Score=161, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013549
- InterPro:   IPR001509
- InterPro:   IPR016040
- InterPro:   IPR010099 [H]

Pfam domain/function: PF08338 DUF1731; PF01370 Epimerase [H]

EC number: NA

Molecular weight: Translated: 32772; Mature: 32772

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVITGGTGLIGRHLIPRLLDLGHQITVVTRNPQKASSVLGPRVTLWQGLADQSNLNGV
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHCCCCCCCCCCH
DAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGD
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
LGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCLLRTGVVLAPDGGILGKMLPP
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCHHCCCCC
FRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLENELRGPFNMVSPYPVRNEQFAHALGHA
HHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
LHRPAILRVPATAIRLLMSESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALENVVQ
HCCCEEEECCHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEEECHHHHHHHHCC
>Mature Secondary Structure
MKIVITGGTGLIGRHLIPRLLDLGHQITVVTRNPQKASSVLGPRVTLWQGLADQSNLNGV
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHCCCCCCCCCCH
DAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGD
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
LGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCLLRTGVVLAPDGGILGKMLPP
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCHHCCCCC
FRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLENELRGPFNMVSPYPVRNEQFAHALGHA
HHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
LHRPAILRVPATAIRLLMSESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALENVVQ
HCCCEEEECCHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]