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The map label for this gene is yohK

Identifier: 218700614

GI number: 218700614

Start: 2345419

End: 2346114

Strand: Direct

Name: yohK

Synonym: ECIAI39_2281

Alternate gene names: 218700614

Gene position: 2345419-2346114 (Clockwise)

Preceding gene: 218700613

Following gene: 218700615

Centisome position: 45.7

GC content: 53.02

Gene sequence:

>696_bases
ATGATGGCGAATATCTGGTGGTCATTACCGCTGACATTGATTGTCTTTTTTGCCGCCCGCAAACTGGCGGCACGGTATAA
GTTTCCCTTGCTTAACCCGTTGCTGGTAGCAATGGTGGTGATCATTCCTTTTTTAATGCTGACCGGCATCTCTTACGACA
GCTACTTTAAAGGTAGCGAAGTGCTAAACGATCTGCTGCAACCGGCGGTCGTTGCGCTGGCCTATCCTTTATATGAGCAG
CTACACCAGATCCGCGCGCGCTGGAAATCGATCATCACCATCTGTTTTATCGGCAGCGTGGTTGCGATGGTGACGGGGAC
TTCCGTGGCATTGTTGATGGGCGCTTCACCGGAAATCGCCGCGTCAATCCTGCCGAAATCAGTCACCACGCCTATTGCAA
TGGCGGTTGGCGGCAGTATTGGCGGTATTCCGGCAATCAGCGCAGTTTGCGTGATTTTCGTCGGTATTCTGGGCGCAGTG
TTTGGTCATACGTTACTTAATGCGATGCGTATTCGCACCAAAGCAGCGCGCGGTCTGGCGATGGGGACAGCCTCGCACGC
CCTCGGTACGGCACGCTGTGCTGAGCTGGATTATCAGGAAGGTGCATTTAGTTCGCTGGCGCTGGTGTTATGCGGGATTA
TTACTTCGCTGATCGCACCGTTCCTTTTCCCGATTATTCTGGCAGTAATGGGCTAA

Upstream 100 bases:

>100_bases
CCTGTGCAGTCAGTACGCTGGTGGTTTTTCTGGTGGTGAGCTGGAGTTCGCAACTGGTGCACGGTGAACGTAAAGTCGTA
GGTCAGAAAGGATCAGAAGA

Downstream 100 bases:

>100_bases
AATTTGCGATGCGTCGCGCATTTTTGATGTAAGTTTCACGCGTTGCATAATTAATGAGATTCAGATCACATATAAAGCCA
TAACGGGTTCGTAAACTGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPFLMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQ
LHQIRARWKSIITICFIGSVVAMVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLIAPFLFPIILAVMG

Sequences:

>Translated_231_residues
MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPFLMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQ
LHQIRARWKSIITICFIGSVVAMVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLIAPFLFPIILAVMG
>Mature_231_residues
MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPFLMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQ
LHQIRARWKSIITICFIGSVVAMVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLIAPFLFPIILAVMG

Specific function: Unknown

COG id: COG1346

COG function: function code M; Putative effector of murein hydrolase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the yohK (E.coli)/ywbG (IPA-22R) (B.subtilis) family

Homologues:

Organism=Escherichia coli, GI1788464, Length=231, Percent_Identity=100, Blast_Score=457, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YOHK_ECOLI (P0AD19)

Other databases:

- EMBL:   U00007
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   X16419
- PIR:   E64982
- RefSeq:   AP_002739.1
- RefSeq:   NP_416647.1
- ProteinModelPortal:   P0AD19
- STRING:   P0AD19
- EnsemblBacteria:   EBESCT00000001116
- EnsemblBacteria:   EBESCT00000017286
- GeneID:   949125
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2130
- KEGG:   eco:b2142
- EchoBASE:   EB1959
- EcoGene:   EG12024
- eggNOG:   COG1346
- GeneTree:   EBGT00050000010135
- HOGENOM:   HBG363009
- OMA:   IINFFLE
- ProtClustDB:   PRK10711
- BioCyc:   EcoCyc:EG12024-MONOMER
- Genevestigator:   P0AD19
- InterPro:   IPR005261
- InterPro:   IPR007300
- TIGRFAMs:   TIGR00659

Pfam domain/function: PF04172 LrgB

EC number: NA

Molecular weight: Translated: 24470; Mature: 24470

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x234568a4)-; HASH(0x1d4bf8e8)-; HASH(0x23870e94)-; HASH(0x2306698c)-; HASH(0x22427fe4)-; HASH(0x235a1f40)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPFLMLTGISYDSYFKGSE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHH
VLNDLLQPAVVALAYPLYEQLHQIRARWKSIITICFIGSVVAMVTGTSVALLMGASPEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHH
ASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAVFGHTLLNAMRIRTKAARGLA
HHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLIAPFLFPIILAVMG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPFLMLTGISYDSYFKGSE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHH
VLNDLLQPAVVALAYPLYEQLHQIRARWKSIITICFIGSVVAMVTGTSVALLMGASPEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHH
ASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAVFGHTLLNAMRIRTKAARGLA
HHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLIAPFLFPIILAVMG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503; 2575702