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The map label for this gene is rutG

Identifier: 218700483

GI number: 218700483

Start: 2193891

End: 2195219

Strand: Direct

Name: rutG

Synonym: ECIAI39_2149

Alternate gene names: 218700483

Gene position: 2193891-2195219 (Clockwise)

Preceding gene: 218700482

Following gene: 218700484

Centisome position: 42.75

GC content: 54.03

Gene sequence:

>1329_bases
ATGGCAATGTTCGGTTTTCCTCACTGGCAGTTAAAATCGACCTCTACAGAGAGCGGCGTGGTCGCGCCGGATGAACGATT
GCCGTTTGCTCAGACGGCAATAATGGGCGTACAACACGCGGTGGCGATGTTTGGCGCGACGGTGTTAATGCCTATTCTGA
TGGGGCTGGATCCCAATCTTTCCATTTTAATGTCGGGGATCGGCACGTTACTGTTTTTCTTTATTACCGGCGGGCGCGTC
CCCAGTTATCTCGGCTCCAGCGCGGCTTTTGTCGGCGTGGTGATTGCCGCGACGGGCTTTAACGGTCAGGGCATTAACCC
GAATATCAGCATCGCGCTGGGCGGGATTATCGCCTGTGGGCTGGTTTATACCGTCATTGGCCTGGTGGTGATGAAAATCG
GTACGCGCTGGATTGAACGGCTAATGCCGCCGGTGGTGACGGGTGCGGTGGTGATGGCGATTGGCCTGAACTTAGCGCCT
ATCGCAGTGAAAAGTGTATCGGCTTCGGCCTTTGATAGCTGGATGGCGGTAATGACGGTGCTGTGTATTGGGCTGGTAGC
GGTATTTACCCGTGGCATGATCCAGCGGTTATTGATTCTCGTAGGATTAATTGTCGCCTGTCTGCTGTATGGCGTGATGA
CCAACGTTTTAGGGCTGGGAAAAGCCGTCGATTTTACTCTCGTCAGCCATGCTGCCTGGTTCGGTCTGCCGCATTTTTCC
ACTCCTGGTTTTAATAGCCAGGCGATGATGTTGATTGCGCCCGTGGCGGTGATTCTGGTGGCGGAAAACTTAGGTCATCT
CAAGGCGGTCGCCGGGATGACCGGACGCAATATGGATCCGTATATGGGACGGGCATTCGTCGGTGATGGTCTGGCAACGA
TGCTTTCCGGCTCTGTCGGCGGTAGCGGCGTCACCACCTATGCTGAAAATATCGGTGTGATGGCCGTGACCAAAGTCTAC
TCGACGCTGGTGTTTGTTGCTGCTGCCGTCATCGCCATGCTGTTGGGCTTTTCGCCGAAATTTGGCGCGCTGATCCATAC
CATTCCGGCCGCGGTGATTGGTGGTGCATCAATTGTTGTGTTCGGGCTGATTGCCGTCGCAGGCGCAAGGATCTGGGTAC
AAAACCGTATCGATTTAAGCCAGAACGGTAATTTGATTATGGTCGCAGTAACCTTAGTGCTGGGCGCGGGTGATTTTGCT
CTCACGCTGGGCGGTTTTACGTTGGGAGGGATCGGTACAGCAACCTTTGGCGCGATTTTACTCAATGCGTTATTAAGCAG
AAGGTTGGTTGACGTTCCACCGCCAGAAGTTATTCATCAGGAGCCATAA

Upstream 100 bases:

>100_bases
CGATTCATCGTCACGCCACCCCCTACGGGCTGGTGTGGTTTGATCGCAGTTATCACGCGCTGATGCGCCCTGCTTGTTAA
CCTCCTTAAGGAGACAGCTG

Downstream 100 bases:

>100_bases
ACAGAAAACCGCCGGGGTTACCGGCGGTGATGGCTTTTTGACGAGCTTAAGAAAAAAATGCATTCGTCATTGATTAGCCC
GGCTAGTTGTCGCTTTTGCC

Product: pyrimidine transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAIMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRV
PSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
TPGFNSQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVY
STLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRIDLSQNGNLIMVAVTLVLGAGDFA
LTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVIHQEP

Sequences:

>Translated_442_residues
MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAIMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRV
PSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
TPGFNSQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVY
STLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRIDLSQNGNLIMVAVTLVLGAGDFA
LTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVIHQEP
>Mature_441_residues
AMFGFPHWQLKSTSTESGVVAPDERLPFAQTAIMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVP
SYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPI
AVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFST
PGFNSQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYS
TLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRIDLSQNGNLIMVAVTLVLGAGDFAL
TLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVIHQEP

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=442, Percent_Identity=98.6425339366516, Blast_Score=856, Evalue=0.0,
Organism=Escherichia coli, GI1788843, Length=423, Percent_Identity=36.4066193853428, Blast_Score=248, Evalue=8e-67,
Organism=Escherichia coli, GI87082181, Length=457, Percent_Identity=26.0393873085339, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082178, Length=404, Percent_Identity=26.7326732673267, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790087, Length=402, Percent_Identity=23.3830845771144, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71993493, Length=174, Percent_Identity=34.4827586206897, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17542260, Length=174, Percent_Identity=34.4827586206897, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17558856, Length=181, Percent_Identity=29.2817679558011, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17542262, Length=176, Percent_Identity=30.1136363636364, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17541904, Length=137, Percent_Identity=33.5766423357664, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356175, Length=176, Percent_Identity=30.1136363636364, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45644; Mature: 45513

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCCCHHHCCCCC
>Mature Secondary Structure 
AMFGFPHWQLKSTSTESGVVAPDERLPFAQTAIMGVQHAVAMFGATVLMPILMGLDPNL
CCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACG
HHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHEEECCCCCCCCCCCEEHHHHHHHHH
LVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
TPGFNSQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVG
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHCHHHHCCCHHHHHCCCCC
GSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHH
FGLIAVAGARIWVQNRIDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAIL
HHHHHHHHHHHEEECCCCCCCCCCEEEEEHHHHHCCCCCEEEECCEEECCHHHHHHHHHH
LNALLSRRLVDVPPPEVIHQEP
HHHHHHCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]