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The map label for this gene is rutC

Identifier: 218700479

GI number: 218700479

Start: 2191571

End: 2191957

Strand: Direct

Name: rutC

Synonym: ECIAI39_2145

Alternate gene names: 218700479

Gene position: 2191571-2191957 (Clockwise)

Preceding gene: 218700478

Following gene: 218700480

Centisome position: 42.7

GC content: 54.26

Gene sequence:

>387_bases
ATGCCAAAATCCGTAATTATTCCCGCTGGCAGCAGCGCACCGCTGGCTCCCTTCGTTCCCGGCACGCTGGCTGATGGCGT
GGTGTATGTCTCCGGTACGCTGGCTTTTGATCAACATAATAACGTGCTGTTTGCCGATGACCCAAAGGCGCAAACCCGCC
ACGTTCTGGAAACCATCCGCAAGGTGATCGAGACGGCGGGTGGCACGATGGCGGACGTGACCTTCAACAGCATCTTTATT
ACCGACTGGAAAAATTACGCCGCGATTAACGAAATCTACGCCGAGTTTTTTCCGGGTGACAAACCGGCGCGATTCTGCAT
TCAGTGCGGACTGGTAAAACCTGACGCACTGGTGGAAATCGCCACAATTGCGCATATCGCCAAGTGA

Upstream 100 bases:

>100_bases
TCAATATCGAAACCTTTTTTGGCTGGGTAAGCGACGTCGAAACGTTCTGCGACGCGCTTTCTCCCACGTCCTTTGCTCGT
ATCGCTTAAGGAGTTTAACG

Downstream 100 bases:

>100_bases
GGCCGCGATGAAACTTTCACTCTCACCTCCCCCTTATGCTGATGCGCCCGTAGTGGTGTTGATTTCGGGTCTTGGCGGTA
GCGGCAGTTACTGGTTACCG

Product: alternative pyrimidine degradation pathway protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFI
TDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK

Sequences:

>Translated_128_residues
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFI
TDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>Mature_127_residues
PKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFIT
DWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK

Specific function: May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation

COG id: COG0251

COG function: function code J; Putative translation initiation inhibitor, yjgF family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RutC family

Homologues:

Organism=Escherichia coli, GI1787245, Length=128, Percent_Identity=100, Blast_Score=264, Evalue=2e-72,
Organism=Escherichia coli, GI87082213, Length=125, Percent_Identity=29.6, Blast_Score=63, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19921376, Length=122, Percent_Identity=36.0655737704918, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUTC_ECO10 (C8U5H2)

Other databases:

- EMBL:   AP010958
- RefSeq:   YP_003221035.1
- ProteinModelPortal:   C8U5H2
- SMR:   C8U5H2
- EnsemblBacteria:   EBESCT00000178117
- GeneID:   8476491
- GenomeReviews:   AP010958_GR
- KEGG:   eoh:ECO103_1056
- GeneTree:   EBGT00050000009258
- ProtClustDB:   CLSK879923
- HAMAP:   MF_00831
- InterPro:   IPR013813
- InterPro:   IPR006175
- InterPro:   IPR019898
- InterPro:   IPR019897
- Gene3D:   G3DSA:3.30.1330.40
- PANTHER:   PTHR11803
- TIGRFAMs:   TIGR03610

Pfam domain/function: PF01042 Ribonuc_L-PSP; SSF55298 YjgF/chorismate_mutase-like

EC number: NA

Molecular weight: Translated: 13763; Mature: 13632

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS01094 UPF0076

Important sites: ACT_SITE 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIR
CCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHH
KVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEI
HHHHHCCCEEEEEEECEEEEECCCCHHHHHHHHHHHCCCCCCCEEHEEECCCCCHHHHHH
ATIAHIAK
HHHHHHCC
>Mature Secondary Structure 
PKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIR
CCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHH
KVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEI
HHHHHCCCEEEEEEECEEEEECCCCHHHHHHHHHHHCCCCCCCEEHEEECCCCCHHHHHH
ATIAHIAK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA