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The map label for this gene is asnC

Identifier: 218697469

GI number: 218697469

Start: 4306838

End: 4307296

Strand: Reverse

Name: asnC

Synonym: EC55989_4218

Alternate gene names: 218697469

Gene position: 4307296-4306838 (Counterclockwise)

Preceding gene: 218697471

Following gene: 218697468

Centisome position: 83.56

GC content: 49.46

Gene sequence:

>459_bases
ATGGAAAATTATCTGATCGACAATCTGGACCGTGGCATCCTGGAAGCATTAATGGGCAATGCGCGCACCGCTTACGCCGA
ACTGGCGAAACAATTTGGCGTCAGTCCGGGGACGATTCACGTTCGAGTAGAGAAAATGAAGCAGGCGGGGATCATTACCG
GGGCGCGTATTGATGTCAGCCCGAAGCAGCTCGGTTATGACGTAGGCTGCTTTATCGGCATTATATTAAAGAGCGCCAAA
GACTACCCTTCCGCGCTGGCAAAGCTGGAAAGCCTTGATGAAGTCACTGAAGCCTATTACACAACCGGCCACTACAGCAT
CTTTATAAAAGTGATGTGCCGTTCGATCGACGCTCTCCAGCATGTACTTATCAACAAGATCCAAACAATTGATGAAATTC
AGTCCACCGAGACATTGATCGTCCTGCAAAACCCGATCATGCGTACCATCAAGCCCTGA

Upstream 100 bases:

>100_bases
CACATGCAATAATCATTCAATAAAAAGCCTAACACACTTTTGATTCATTAAAAAAGAAGGCTAAAATAGAATGAATCATC
AATCTGCATAAGAAAATCCT

Downstream 100 bases:

>100_bases
TCGGCTTTTTTAATCCCATACTTTTCCACAGGTAGATCCCAACGCGTTCACAGCGTACAATACGCCACTCTTAATAAAGG
TGGCGGTTTATGGCAGATAT

Product: DNA-binding transcriptional regulator AsnC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVEKMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAK
DYPSALAKLESLDEVTEAYYTTGHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP

Sequences:

>Translated_152_residues
MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVEKMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAK
DYPSALAKLESLDEVTEAYYTTGHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP
>Mature_152_residues
MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVEKMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAK
DYPSALAKLESLDEVTEAYYTTGHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP

Specific function: Activator of asnA transcription; autogenous regulator of its own transcription; and repressor of the expression of gidA at a post-transcriptional level

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790182, Length=152, Percent_Identity=100, Blast_Score=313, Evalue=4e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASNC_ECO57 (P0ACI8)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   E91214
- PIR:   F86060
- RefSeq:   NP_290382.1
- RefSeq:   NP_312712.1
- ProteinModelPortal:   P0ACI8
- SMR:   P0ACI8
- EnsemblBacteria:   EBESCT00000027647
- EnsemblBacteria:   EBESCT00000059359
- GeneID:   915327
- GeneID:   960424
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5244
- KEGG:   ecs:ECs4685
- GeneTree:   EBGT00050000010711
- HOGENOM:   HBG740878
- OMA:   EARTPFA
- ProtClustDB:   PRK11179
- BioCyc:   ECOL83334:ECS4685-MONOMER
- GO:   GO:0005622
- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00033
- SMART:   SM00344

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11; SSF54909 Dimer_A_B_barrel

EC number: NA

Molecular weight: Translated: 16888; Mature: 16888

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00519 HTH_ASNC_1; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVEKMKQAGIITGARIDVS
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCEECCEECCC
PKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTTGHYSIFIKVMCRSIDALQ
HHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HVLINKIQTIDEIQSTETLIVLQNPIMRTIKP
HHHHHHHHHHHHHHCCCEEEEECCCHHHHCCC
>Mature Secondary Structure
MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVEKMKQAGIITGARIDVS
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCEECCEECCC
PKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTTGHYSIFIKVMCRSIDALQ
HHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HVLINKIQTIDEIQSTETLIVLQNPIMRTIKP
HHHHHHHHHHHHHHCCCEEEEECCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796