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The map label for this gene is lpfA

Identifier: 218697454

GI number: 218697454

Start: 4291260

End: 4291832

Strand: Reverse

Name: lpfA

Synonym: EC55989_4203

Alternate gene names: 218697454

Gene position: 4291832-4291260 (Counterclockwise)

Preceding gene: 218697455

Following gene: 218697453

Centisome position: 83.26

GC content: 47.82

Gene sequence:

>573_bases
ATGAAGCGTAATATTATAGGCGGTGCATTCACTCTGGCATCTCTAATGCTGGCCGGGCATGCACTGGCAGAAGATGGTGT
TGTTCACTTCGTCGGTGAAATTGTCGACACTACTTGTGAAGTTACCTCCGATACAGCCGATCAAATTGTCCCACTGGGTA
AAGTCAGTAAAAATGCATTTTCAGGTGTAGGTAGTCTGGCGTCGCCACAGAAGTTCAGTATTAAACTTGAAAATTGCCCG
GCAACGTACACTCAAGCAGCCGTTCGTTTTGATGGTACAGAAGCGCCTGGCGGCGACGGCGACCTGAAAGTGGGTACGCC
GCTTACAGCAGGCAACCCTGGTGATATTACCGGTACAGGACAAGCGATTGCGGCAACCGGCGTTGGTATTCGTATTTTTA
ACCAGTCCGATAATTCGCAGGTTAAACTTTATAACGACTCTGCTTATACCGCTATCGATGCTGAAGGCAAGGCTGAAATG
AAGTTTATTGCACGCTATGTGGCAACCAATGCGACCGTAACGGCTGGTACGGCGAACGCGGATTCACAATTTACTGTCGA
ATATAAGAAATAA

Upstream 100 bases:

>100_bases
AAGCCGTCTCTTTGGTGTACTATTCCTTTGAATCAAAAATACACTTATTAATATAAGTGATGATTCATGGTAAAGGATAT
ATTATATCAATGGAGTTTTT

Downstream 100 bases:

>100_bases
TTTATCAAGGGCCTTTTTATTCAGTTGGCTTTGGCCAGGGAGTCGTTATGTCCAGAAAAAGTTGTTTAATCAGGCTCTTT
AAAACAACAGTTTCATGTAA

Product: Putative major fimbrial subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKRNIIGGAFTLASLMLAGHALAEDGVVHFVGEIVDTTCEVTSDTADQIVPLGKVSKNAFSGVGSLASPQKFSIKLENCP
ATYTQAAVRFDGTEAPGGDGDLKVGTPLTAGNPGDITGTGQAIAATGVGIRIFNQSDNSQVKLYNDSAYTAIDAEGKAEM
KFIARYVATNATVTAGTANADSQFTVEYKK

Sequences:

>Translated_190_residues
MKRNIIGGAFTLASLMLAGHALAEDGVVHFVGEIVDTTCEVTSDTADQIVPLGKVSKNAFSGVGSLASPQKFSIKLENCP
ATYTQAAVRFDGTEAPGGDGDLKVGTPLTAGNPGDITGTGQAIAATGVGIRIFNQSDNSQVKLYNDSAYTAIDAEGKAEM
KFIARYVATNATVTAGTANADSQFTVEYKK
>Mature_190_residues
MKRNIIGGAFTLASLMLAGHALAEDGVVHFVGEIVDTTCEVTSDTADQIVPLGKVSKNAFSGVGSLASPQKFSIKLENCP
ATYTQAAVRFDGTEAPGGDGDLKVGTPLTAGNPGDITGTGQAIAATGVGIRIFNQSDNSQVKLYNDSAYTAIDAEGKAEM
KFIARYVATNATVTAGTANADSQFTVEYKK

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI87081753, Length=173, Percent_Identity=32.9479768786127, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI87082421, Length=198, Percent_Identity=30.3030303030303, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789531, Length=189, Percent_Identity=30.6878306878307, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1786746, Length=162, Percent_Identity=30.8641975308642, Blast_Score=61, Evalue=4e-11,
Organism=Escherichia coli, GI1790773, Length=181, Percent_Identity=28.1767955801105, Blast_Score=60, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 19629; Mature: 19629

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRNIIGGAFTLASLMLAGHALAEDGVVHFVGEIVDTTCEVTSDTADQIVPLGKVSKNAF
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCHHH
SGVGSLASPQKFSIKLENCPATYTQAAVRFDGTEAPGGDGDLKVGTPLTAGNPGDITGTG
HCCCCCCCCCEEEEEECCCCCCHHEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCC
QAIAATGVGIRIFNQSDNSQVKLYNDSAYTAIDAEGKAEMKFIARYVATNATVTAGTANA
CEEEECCCEEEEEECCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHCCCEEEECCCCC
DSQFTVEYKK
CCEEEEEECC
>Mature Secondary Structure
MKRNIIGGAFTLASLMLAGHALAEDGVVHFVGEIVDTTCEVTSDTADQIVPLGKVSKNAF
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCHHH
SGVGSLASPQKFSIKLENCPATYTQAAVRFDGTEAPGGDGDLKVGTPLTAGNPGDITGTG
HCCCCCCCCCEEEEEECCCCCCHHEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCC
QAIAATGVGIRIFNQSDNSQVKLYNDSAYTAIDAEGKAEMKFIARYVATNATVTAGTANA
CEEEECCCEEEEEECCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHCCCEEEECCCCC
DSQFTVEYKK
CCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1982455 [H]