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The map label for this gene is yhhX

Identifier: 218697124

GI number: 218697124

Start: 3918187

End: 3919224

Strand: Reverse

Name: yhhX

Synonym: EC55989_3849

Alternate gene names: 218697124

Gene position: 3919224-3918187 (Counterclockwise)

Preceding gene: 218697130

Following gene: 218697123

Centisome position: 76.03

GC content: 51.16

Gene sequence:

>1038_bases
ATGGTCATCAACTGCGCCTTTATTGGCTTCGGCAAAAGCACCACCCGTTACCATCTGCCGTATGTACTTAACCGCAAGGA
TAGCTGGCATGTCGCGCATATTTTTCGTCGCCATGCGAAGCCGGAAGAACAGGCTCCCATTTATTCCCATATCCATTTCA
CCAGCGATCTCGACGAAGTACTAAACGATCCCGATGTTAAGCTGGTTGTTGTCTGCACCCACGCGGACAGCCATTTCGAG
TACGCGAAACGCGCGCTGGAAGCCGGGAAAAATGTGCTGGTCGAAAAACCGTTCACCCCGACGCTTGCCCAGGCGAAGGA
GCTGTTTGCGTTGGCGAAAAGCAAAGGGCTGACCGTCACGCCGTATCAGAATCGTCGCTTTGACTCCTGCTTCCTGACAG
CGAAAAAAGCGATTGAAAGTGGCAAGTTGGGAGAGATTGTTGAAGTGGAAAGCCATTTTGACTATTACCGCCCGGTGGCA
GAGACCAAACCTGGGCTGCCGCAGGATGGCGCGTTTTATGGCCTTGGTGTGCATACGATGGACCAGATTATTTCTCTGTT
CGGTCGCCCGGATCACGTCGCTTATGACATCCGCAGCCTGCGTAATAAAGCCAATCCTGACGACACCTTTGAAGCGCAAC
TGTTTTATGGCGACCTGAAAGCCATCGTCAAAACCAGCCATCTGGTGAAAATCGATTATCCGAAATTTATCGTTCACGGT
AAGAAAGGTTCGTTTATTAAATACGGTATCGACCAGCAGGAAACCAGCCTGAAGGCTAATATTATGCCGGGCGAACCGGG
ATTCGCAGCGGATGATTCGGTCGGTGTGCTGGAGTATGTCAATGACGAGGGCGTGACGGTCAGAGAAGAGATGAAGCCGG
AGATGGGCGATTACGGGCGCGTTTATGATGCGTTGTATCAAACCATCACCCACGGTGCGCCAAATTACGTCAAGGAATCT
GAAGTTCTTACCAATCTGGAAATCCTTGAACGCGGATTTGAGCAAGCCTCTCCCTCCACAGTAACTCTCGCTAAGTAA

Upstream 100 bases:

>100_bases
TTTATCCACGGGAGTGCTTGTGTTCGTTATGCGCACTCCAGTAGGAACCACGTCCGCTTTGCGCTAAGGTGTAAATAACC
ACCTTAAAAAGGACGAAATC

Downstream 100 bases:

>100_bases
GTTTGATGGCCCCTCGAATAGTTCAATTTTTTTGAACAGAGGGGTCAATTTTCACCCTCTATCATCCCAGGCAGATCGGG
TCCACACTAAGCTCATCGAA

Product: putative dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLDEVLNDPDVKLVVVCTHADSHFE
YAKRALEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIVHG
KKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITHGAPNYVKES
EVLTNLEILERGFEQASPSTVTLAK

Sequences:

>Translated_345_residues
MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLDEVLNDPDVKLVVVCTHADSHFE
YAKRALEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIVHG
KKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITHGAPNYVKES
EVLTNLEILERGFEQASPSTVTLAK
>Mature_345_residues
MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLDEVLNDPDVKLVVVCTHADSHFE
YAKRALEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIVHG
KKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITHGAPNYVKES
EVLTNLEILERGFEQASPSTVTLAK

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family. Biliverdin reductase subfamily

Homologues:

Organism=Escherichia coli, GI1789848, Length=345, Percent_Identity=100, Blast_Score=716, Evalue=0.0,
Organism=Escherichia coli, GI87081947, Length=337, Percent_Identity=35.6083086053413, Blast_Score=192, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6323975, Length=221, Percent_Identity=30.316742081448, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHHX_ECOLI (P46853)

Other databases:

- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C65140
- RefSeq:   AP_004352.1
- RefSeq:   NP_417897.1
- PDB:   3F4L
- PDBsum:   3F4L
- ProteinModelPortal:   P46853
- SMR:   P46853
- DIP:   DIP-12357N
- IntAct:   P46853
- STRING:   P46853
- EnsemblBacteria:   EBESCT00000001199
- EnsemblBacteria:   EBESCT00000017322
- GeneID:   947944
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3403
- KEGG:   eco:b3440
- EchoBASE:   EB2778
- EcoGene:   EG12944
- eggNOG:   COG0673
- GeneTree:   EBGT00050000009259
- HOGENOM:   HBG322267
- OMA:   EEIKPEM
- ProtClustDB:   PRK10206
- BioCyc:   EcoCyc:G7757-MONOMER
- Genevestigator:   P46853
- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38765; Mature: 38765

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLDEV
CEEEEEEEECCCCCCEEECCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHH
LNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVT
HCCCCEEEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEC
PYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAETKPGLPQDGAFYGLGVHTM
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHCCHHHCCCCCCCCCCEEECCHHHH
DQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIVHG
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHCCEEEECCCEEEEEC
KKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLEYVNDEGVTVREEMKPEMGDYGR
CCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCEEHHHCCCCCCCHHH
VYDALYQTITHGAPNYVKESEVLTNLEILERGFEQASPSTVTLAK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLDEV
CEEEEEEEECCCCCCEEECCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHH
LNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVT
HCCCCEEEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEC
PYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAETKPGLPQDGAFYGLGVHTM
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHCCHHHCCCCCCCCCCEEECCHHHH
DQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIVHG
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHCCEEEECCCEEEEEC
KKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLEYVNDEGVTVREEMKPEMGDYGR
CCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCEEHHHCCCCCCCHHH
VYDALYQTITHGAPNYVKESEVLTNLEILERGFEQASPSTVTLAK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 10493123