BacMap

Definition	Escherichia coli 55989, complete genome.
Accession	NC_011748
Length	5,154,862

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The map label for this gene is yghA

Identifier: 218696713

GI number: 218696713

Start: 3502216

End: 3503100

Strand: Direct

Name: yghA

Synonym: EC55989_3421

Alternate gene names: 218696713

Gene position: 3502216-3503100 (Clockwise)

Preceding gene: 218696711

Following gene: 218696717

Centisome position: 67.94

GC content: 54.46

Gene sequence:

>885_bases
ATGTCTCATTTAAAAGACCCGACCACGCAGTATTACACTGGTGAATATCCCAAACAGAAACAACCGACGCCAGGCATCCA
GGCGAAGATGACACCGGTACCGGATTGCGGCGAGAAAACCTATGTTGGTAGCGGTCGCCTGAAAGATCGTAAAGCACTGG
TGACAGGGGGCGATTCCGGAATAGGTCGCGCTGCCGCCATCGCTTACGCGCGTGAAGGGGCTGACGTGGCGATCAGTTAT
CTTCCCGTGGAAGAAGAAGACGCTCAGGATGTGAAAAAGATCATTGAAGAATGCGGACGCAAAGCCGTTCTGCTGCCAGG
CGATTTAAGCGATGAGAAATTCGCCCGTTCGCTGGTTCACGAAGCGCACAAGGCGTTAGGCGGGCTGGATATTATGGCGC
TGGTCGCCGGGAAACAGGTTGCCATTCCGGATATTGCAGACCTCACCAGCGAACAGTTTCAAAAGACCTTTGCCATTAAC
GTTTTCGCGCTGTTCTGGCTAACCCAGGAAGCGATCCCCCTGCTACCGAAAGGTGCAAGTATCATCACCACTTCGTCAAT
CCAGGCATACCAGCCAAGTCCGCATTTACTGGACTATGCGGCTACGAAGGCGGCGATTCTGAACTACAGCCGTGGCCTGG
CAAAACAGGTCGCGGAGAAAGGTATTCGGGTGAATATTGTCGCGCCAGGCCCGATCTGGACAGCACTGCAAATTTCCGGC
GGACAAACGCAGGATAAGATCCCGCAGTTTGGTCAGAAAACGCCGATGAAGCGTGCGGGGCAACCGGCGGAACTGGCCCC
TGTATATGTTTATCTGGCAAGTCAGGAGTCGAGCTACGTCACCGCAGAAGTGCACGGTGTGTGCGGCGGCGAGCATTTAG
GTTAA

Upstream 100 bases:

>100_bases
TGTCGCATAATTCTGAGGTTTAGGGATCTTCCTGGTTCCCTTATCAACGCATCGAGAGCGTCTACCCTTAAAGGACGTTG
AACCTGAAGGGAGAAAAACG

Downstream 100 bases:

>100_bases
AAAAATGCCCGGTTGTGAAAAGCAACCGGGCATCATTTTTATTTCGCTTTGGCGGTTTCTTCGCCGACCAGACCTATCTT
CAGGTAACCCGCCTGATGCA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISY
LPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG
GQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG

Sequences:

>Translated_294_residues
MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISY
LPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG
GQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
>Mature_293_residues
SHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYL
PVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAINV
FALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISGG
QTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.1285140562249, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.1204819277108, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=30.3846153846154, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=27.0992366412214, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=26.984126984127, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=29.2, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=29.7979797979798, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=32.4742268041237, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=28.8537549407115, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=31.7204301075269, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=28.0632411067194, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=262, Percent_Identity=28.6259541984733, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32455239, Length=185, Percent_Identity=26.4864864864865, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI5031765, Length=185, Percent_Identity=26.4864864864865, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=26.2032085561497, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=28.1124497991968, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1789378, Length=294, Percent_Identity=99.6598639455782, Blast_Score=598, Evalue=1e-172,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=35.3658536585366, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=31.3008130081301, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=32.9317269076305, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=28.9795918367347, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=28.8461538461538, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=29.6747967479675, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=27.710843373494, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786812, Length=264, Percent_Identity=28.030303030303, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=26.6129032258064, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=26.8292682926829, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787526, Length=239, Percent_Identity=32.6359832635983, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786701, Length=213, Percent_Identity=28.169014084507, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=251, Percent_Identity=30.2788844621514, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=31.5985130111524, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=30.3149606299213, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=28.0769230769231, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=28.8973384030418, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=30.6818181818182, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551412, Length=281, Percent_Identity=29.1814946619217, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=29.6992481203008, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=31.4606741573034, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=30.3703703703704, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=248, Percent_Identity=30.6451612903226, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=32.4528301886792, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=25.7936507936508, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=252, Percent_Identity=28.1746031746032, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=30.46875, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=28.6792452830189, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=31.8181818181818, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=258, Percent_Identity=27.5193798449612, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=29.6992481203008, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=29.2592592592593, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=263, Percent_Identity=30.0380228136882, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=29.811320754717, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=30.6122448979592, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=247, Percent_Identity=29.9595141700405, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=27.6515151515151, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=24.7967479674797, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=28.6821705426357, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=31.3253012048193, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=29.8804780876494, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=31.5573770491803, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=30.6772908366534, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=29.4820717131474, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=29.3650793650794, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17737361, Length=268, Percent_Identity=27.9850746268657, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24644337, Length=118, Percent_Identity=36.4406779661017, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24643142, Length=236, Percent_Identity=29.2372881355932, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584748, Length=209, Percent_Identity=28.7081339712919, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076933, Length=209, Percent_Identity=28.7081339712919, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=26.9035532994924, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21357673, Length=198, Percent_Identity=26.2626262626263, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31488; Mature: 31357

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSG
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCCCEEEEECCCCC
IGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVH
CCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
EAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAINVFALFWLTQEAIPLLPKGAS
HHHHHHCCHHEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
IITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG
EEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECC
GQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
CCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
SHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSG
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCCCEEEEECCCCC
IGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVH
CCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
EAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAINVFALFWLTQEAIPLLPKGAS
HHHHHHCCHHEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
IITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG
EEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECC
GQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
CCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]