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The map label for this gene is hha [H]

Identifier: 218696648

GI number: 218696648

Start: 3433294

End: 3433506

Strand: Reverse

Name: hha [H]

Synonym: EC55989_3351

Alternate gene names: 218696648

Gene position: 3433506-3433294 (Counterclockwise)

Preceding gene: 218696650

Following gene: 218696647

Centisome position: 66.61

GC content: 46.95

Gene sequence:

>213_bases
ATGGAAGTTAAAACCAAAGAAGACTGGCTGTATCAGTTCCGTCGTTGTTCATCCCGGGAGACGCTGGAAAAAGTGATTTC
CCACACACGTTATAAACTTACCCTTGCGGAGCTGGAAGCCTTCAACTCTGCGGTTGATCACCGACTGGCAGAACTAACCA
TGAACAAACTTTACGATCGCGTTCCGGCTTCTGTCTGGAAATATGTTACCTGA

Upstream 100 bases:

>100_bases
GGTGCGGGAGTAATGAGTTTGGGGTGGGTACCAGAATGCCAGTCAGGTGCGGTATGCTGGCAGTATCACGTTAATTGCAG
CATAAAGTGATGAGAGGCTA

Downstream 100 bases:

>100_bases
ACGTTCGGTAATCACAGCGGTATTGTGCCGGGCGTTATATGCCTGTGATTCTTTTGCTCTTCTCTGGTTGCTGCAAAGCT
GAATATGTTCCTGTTGTTGG

Product: haemolysin expression-modulating protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 70; Mature: 70

Protein sequence:

>70_residues
MEVKTKEDWLYQFRRCSSRETLEKVISHTRYKLTLAELEAFNSAVDHRLAELTMNKLYDRVPASVWKYVT

Sequences:

>Translated_70_residues
MEVKTKEDWLYQFRRCSSRETLEKVISHTRYKLTLAELEAFNSAVDHRLAELTMNKLYDRVPASVWKYVT
>Mature_70_residues
MEVKTKEDWLYQFRRCSSRETLEKVISHTRYKLTLAELEAFNSAVDHRLAELTMNKLYDRVPASVWKYVT

Specific function: Down-regulates hemolysin production and can also stimulate transposition events in vivo. May bind DNA and influence DNA topology in response to environmental stimuli [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hha/ymoA/cnu family [H]

Homologues:

Organism=Escherichia coli, GI1786665, Length=65, Percent_Identity=58.4615384615385, Blast_Score=86, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007985 [H]

Pfam domain/function: PF05321 HHA [H]

EC number: NA

Molecular weight: Translated: 8397; Mature: 8397

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVKTKEDWLYQFRRCSSRETLEKVISHTRYKLTLAELEAFNSAVDHRLAELTMNKLYDR
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPASVWKYVT
HHHHHHHCCC
>Mature Secondary Structure
MEVKTKEDWLYQFRRCSSRETLEKVISHTRYKLTLAELEAFNSAVDHRLAELTMNKLYDR
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPASVWKYVT
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]