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The map label for this gene is ygeW

Identifier: 218696466

GI number: 218696466

Start: 3230403

End: 3231593

Strand: Direct

Name: ygeW

Synonym: EC55989_3157

Alternate gene names: 218696466

Gene position: 3230403-3231593 (Clockwise)

Preceding gene: 218696464

Following gene: 218696467

Centisome position: 62.67

GC content: 49.87

Gene sequence:

>1191_bases
ATGATGAAAACTGTTAATGAGCTGATTAAGGATATCAATTCGCTGACCTCTCACCTTCACGAGAAAGATTTTTTGTTAAC
GTGGGAACAGACGCCAGATGAACTGAAACAAGTACTGGACGTTGCCGCAGCATTAAAAGCACTGCGTGCTGAAAACATCT
CAACCAAAGTCTTTAATAGTGGATTAGGTATTTCCGTATTCCGCGACAACTCCACCCGTACCCGCTTCTCTTATGCTTCC
GCGCTTAACCTGCTCGGCCTTGCACAACAAGATCTCGACGAAGGCAAATCACAAATCGCTCACGGCGAAACCGTGCGTGA
AACCGCCAATATGATCTCCTTCTGCGCCGACGCTATTGGTATTCGCGACGATATGTATCTGGGCGCAGGCAACGCCTATA
TGCGTGAAGTTGGCGCTGCACTTGATGACGGTTACAAGCAGGGTGTACTGCCACAGCGTCCGGCTTTAGTGAACCTGCAA
TGCGATATTGACCACCCGACTCAGTCAATGGCTGACCTCGCGTGGTTACGTGAACACTTTGGTTCACTGGAAAACCTGAA
AGGTAAAAAAATCGCCATGACCTGGGCCTACTCTCCAAGCTATGGCAAACCGCTCTCTGTACCACAAGGCATCATCGGTC
TGATGACTCGCTTCGGTATGGATGTCACCCTGGCCCATCCGGAAGGCTACGACCTGATCCCGGATGTGGTTGAAGTGGCG
AAAAACAATGCTAAAGCATCTGGCGGTAGCTTCCGTCAGGTCACCAGCATGGAAGAAGCGTTCAAAGATGCAGACATCGT
TTATCCGAAGTCATGGGCACCTTACAAAGTGATGGAACAGCGTACCGAATTGCTGCGCGCTAACGATCACGAAGGCTTAA
AAGCACTGGAAAAACAGTGTCTGGCACAGAACGCGCAACACAAAGACTGGCATTGTACTGAAGAGATGATGGAACTGACC
CGTGATGGCGAAGCCCTGTACATGCACTGCCTGCCAGCTGATATCAGCGGCGTATCCTGTAAAGAAGGTGAAGTGACTGA
AGGCGTATTCGAAAAATACCGTATCGCAACCTACAAAGAAGCCAGCTGGAAGCCTTATATCATCGCCGCGATGATCCTGT
CCCGTAAATACGCCAAACCAGGTGCACTGCTCGAGCAACTGCTGAAAGAAGCGCAAGAACGCGTGAAATAA

Upstream 100 bases:

>100_bases
ACTTATTGTTAGTCCCAGGTATAGCTGTGAAAACACCAATCACTTTGGCAAGTCACAGTGAAATAAACCACTTTGCCTGT
CATTCCACTACCGGGACTTT

Downstream 100 bases:

>100_bases
CCCCTCGGGCCGATCAGCTGGTCGGCCCTCTATTTCCAGAGGCCAAAAGGATAGGATATGTCCGTTTTCTCATTGAAGAT
TGATATCGCCGATAACAAAT

Product: aspartate/ornithine carbamoyltransferase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MMKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYAS
ALNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQ
CDIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVA
KNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELT
RDGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK

Sequences:

>Translated_396_residues
MMKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYAS
ALNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQ
CDIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVA
KNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELT
RDGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK
>Mature_396_residues
MMKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYAS
ALNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQ
CDIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVA
KNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELT
RDGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK

Specific function: Unknown

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family

Homologues:

Organism=Homo sapiens, GI38788445, Length=364, Percent_Identity=25.5494505494505, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI48994908, Length=396, Percent_Identity=99.7474747474748, Blast_Score=827, Evalue=0.0,
Organism=Escherichia coli, GI1790703, Length=376, Percent_Identity=24.7340425531915, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786469, Length=377, Percent_Identity=24.6684350132626, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=310, Percent_Identity=23.5483870967742, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YGEW_ECO57 (Q8X6C0)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C85942
- PIR:   G91096
- RefSeq:   NP_289440.1
- RefSeq:   NP_311770.1
- ProteinModelPortal:   Q8X6C0
- SMR:   Q8X6C0
- EnsemblBacteria:   EBESCT00000028952
- EnsemblBacteria:   EBESCT00000059529
- GeneID:   916433
- GeneID:   958325
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4209
- KEGG:   ecs:ECs3743
- GeneTree:   EBGT00050000009122
- HOGENOM:   HBG579429
- OMA:   VAMTWAY
- ProtClustDB:   PRK07200
- BioCyc:   ECOL83334:ECS3743-MONOMER
- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002082
- InterPro:   IPR017702
- PRINTS:   PR00100
- PRINTS:   PR00101
- TIGRFAMs:   TIGR03316

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N; SSF53671 Asp/Orn_carbamoyltranf

EC number: NA

Molecular weight: Translated: 44187; Mature: 44187

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNS
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
GLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIG
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
IRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQCDIDHPTQSMADLAWLREHF
CCCCCEECCCHHHHHHHHHHHHCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
GSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVA
CCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHH
KNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQC
HCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKE
HHCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEECC
ASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNS
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
GLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIG
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
IRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQCDIDHPTQSMADLAWLREHF
CCCCCEECCCHHHHHHHHHHHHCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
GSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVA
CCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHH
KNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQC
HCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKE
HHCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEECC
ASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796