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The map label for this gene is suhB

Identifier: 218696160

GI number: 218696160

Start: 2886795

End: 2887598

Strand: Direct

Name: suhB

Synonym: EC55989_2818

Alternate gene names: 218696160

Gene position: 2886795-2887598 (Clockwise)

Preceding gene: 218696148

Following gene: 218696161

Centisome position: 56.0

GC content: 53.98

Gene sequence:

>804_bases
ATGCATCCGATGCTGAACATCGCCGTGCGCGCAGCGCGCAAGGCGGGTAATTTAATTGCCAAAAACTATGAAACCCCGGA
CGCTGTAGAAGCGAGCCAGAAAGGCAGTAACGATTTCGTGACCAACGTAGATAAAGCTGCCGAAGCGGTGATTATCGACA
CGATTCGTAAATCTTACCCACAGCACACCATCATCACCGAAGAAAGCGGTGAACTTGAAGGTACTGATCAGGATGTTCAA
TGGGTTATCGATCCACTGGATGGTACTACCAACTTTATCAAACGTCTGCCGCACTTCGCGGTATCTATCGCCGTTCGTAT
CAAAGGCCGCACCGAAGTTGCTGTGGTATACGATCCTATGCGTAACGAACTGTTCACCGCCACTCGCGGTCAGGGCGCAC
AGCTGAACGGCTACCGTCTGCGCGGTAGCACCGCTCGCGATCTCGACGGTACCATTCTGGCGACCGGCTTCCCGTTCAAA
GCAAAACAGTACGCCACTACCTACATCAACATCGTCGGCAAACTGTTCAACGAATGTGCAGACTTCCGTCGTACCGGTTC
TGCGGCGCTGGATCTGGCTTACGTCGCTGCGGGTCGTGTTGACGGTTTCTTTGAAATCGGTCTGCGTCCGTGGGATTTCG
CGGCAGGCGAGCTGCTGGTTCGTGAAGCGGGCGGCATCGTCAGCGACTTCACCGGTGGTCATAACTATATGCTGACCGGT
AACATCGTTGCTGGTAACCCACGTGTTGTGAAAGCCATGCTGGCGAACATGCGTGACGAGTTAAGCGACGCTCTGAAGCG
TTAA

Upstream 100 bases:

>100_bases
GATTATTCACGCATCTTATCATAAAACGAAGACAGATGCCGATCTCGCTGCTATACTCTGCGCCGTTTTCCCGTTCTTTA
ACATCCAGTGAGAGAGACCG

Downstream 100 bases:

>100_bases
TGACTCAGGCGGGTGATGTCACTCACCCGCCCTCGCCTTTCAGGCGCTATTCTGAAATACTTCCTCACCGCTTTACTTTC
TTTCGTCACTCTCCCACCAT

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQ
WVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNYMLTG
NIVAGNPRVVKAMLANMRDELSDALKR

Sequences:

>Translated_267_residues
MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQ
WVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNYMLTG
NIVAGNPRVVKAMLANMRDELSDALKR
>Mature_267_residues
MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQ
WVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNYMLTG
NIVAGNPRVVKAMLANMRDELSDALKR

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family

Homologues:

Organism=Homo sapiens, GI5031789, Length=257, Percent_Identity=32.6848249027237, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI221625487, Length=257, Percent_Identity=32.6848249027237, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI7657236, Length=254, Percent_Identity=34.251968503937, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI221625507, Length=142, Percent_Identity=36.6197183098592, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1788882, Length=267, Percent_Identity=100, Blast_Score=548, Evalue=1e-157,
Organism=Escherichia coli, GI1790659, Length=131, Percent_Identity=35.8778625954198, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193202572, Length=239, Percent_Identity=33.4728033472803, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI193202570, Length=239, Percent_Identity=32.6359832635983, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320493, Length=203, Percent_Identity=33.4975369458128, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321836, Length=206, Percent_Identity=33.0097087378641, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357329, Length=245, Percent_Identity=34.6938775510204, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24664922, Length=270, Percent_Identity=31.1111111111111, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24664926, Length=237, Percent_Identity=32.0675105485232, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI21357303, Length=237, Percent_Identity=35.0210970464135, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI21357957, Length=280, Percent_Identity=32.1428571428571, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24664918, Length=257, Percent_Identity=33.0739299610895, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUHB_ECO57 (P0ADG6)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   G91053
- RefSeq:   NP_311426.1
- ProteinModelPortal:   P0ADG6
- SMR:   P0ADG6
- EnsemblBacteria:   EBESCT00000028439
- EnsemblBacteria:   EBESCT00000056077
- GeneID:   915157
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ecs:ECs3399
- GeneTree:   EBGT00050000010909
- HOGENOM:   HBG730251
- OMA:   TGFPFKQ
- ProtClustDB:   PRK10757
- BioCyc:   ECOL83334:ECS3399-MONOMER
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337
- PANTHER:   PTHR20854
- PRINTS:   PR00377
- PRINTS:   PR01959

Pfam domain/function: PF00459 Inositol_P

EC number: =3.1.3.25

Molecular weight: Translated: 29172; Mature: 29172

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00629 IMP_1; PS00630 IMP_2

Important sites: BINDING 67-67 BINDING 183-183 BINDING 212-212

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYP
CCCHHHHHHHHHHHHCCEEECCCCCCCHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHCCC
QHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPM
CCEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCEEEEEEEEECCCEEEEEEECCC
RNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFKAKQYATTYINIVGKLFNECA
CCCEEEECCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
DFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNYMLTG
HHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCEEECCCCCCCEEEEC
NIVAGNPRVVKAMLANMRDELSDALKR
CEEECCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYP
CCCHHHHHHHHHHHHCCEEECCCCCCCHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHCCC
QHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPM
CCEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCEEEEEEEEECCCEEEEEEECCC
RNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFKAKQYATTYINIVGKLFNECA
CCCEEEECCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
DFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNYMLTG
HHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCEEECCCCCCCEEEEC
NIVAGNPRVVKAMLANMRDELSDALKR
CEEECCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796