Click here to switch to the map view.

The map label for this gene is focB

Identifier: 218696119

GI number: 218696119

Start: 2837797

End: 2838528

Strand: Direct

Name: focB

Synonym: EC55989_2777

Alternate gene names: 218696119

Gene position: 2837797-2838528 (Clockwise)

Preceding gene: 218696118

Following gene: 218696121

Centisome position: 55.05

GC content: 50.68

Gene sequence:

>732_bases
ATGAGAAACAAACTCTCTTTCGACTTGCAGTTGAGCGCCAGAAAAGCGGCAATCGCTGAACGGATTGCCTCCCATAAAAT
TGCCCGCAGTAAAGTGTCGGTCTTTTTAATGGCGATGTCCGCTGGCGTGTTTATGGCGATCGGATTTACTTTTTACCTTT
CCGTTATCGCCGATGCCCCGTCTTCACAGGCATTAACCCATCTGGTGGGCGGCCTTTGCTTTACACTCGGCTTTATTTTG
CTGGCGGTTTGTGGCACCAGCCTGTTCACCTCGTCGGTAATGACGGTGATGGCAAAAAGTCGGGGCGTTATTAGTTGGCG
AACTTGGCTGATTAACGCACTTCTGGTGGCCTGCGGTAATCTGGCAGGTATTGCCTGTTTCAGTTTGTTAATCTGGTTTT
CCGGGCTGGTGATGAGTGAAAACGCGATGTGGGGAGTCGCGGTTTTACACTGCGCCGAGGGCAAAATGCATCATACATTT
ACTGAATCTGTCAGCCTCGGCATTATGTGCAATCTGATGGTTTGCCTGGCGCTGTGGATGAGTTATTGCGGGCGTTCATT
ATGCGACAAAATCGTCGCTATGATTTTGCCCATCACCCTGTTTGTCGCCAGTGGCTTTGAGCACTGTATCGCCAATTTGT
TTGTGATTCCGTTCGCCATTGCCATTCGCCATTTTGCCCCACGCCCCTTCGGCAACTGGCGCACAGTAGCGCAGACAATT
TTCCGGCACTGA

Upstream 100 bases:

>100_bases
GACACGATTAGGGATGAAGCGCACCACGCTGCTGTCACGAATGCAGCGTCTGGGGATCTCGGTTCGCGAGGTGTTGTAAT
CTGCTTTTGCAGGAGTATGC

Downstream 100 bases:

>100_bases
CGGTCAGCCATTTTATTACCGCCAATCTGCTCCCGGTGATGCTGGGTAATATTATCGGCGGTGCAGTGCTGGTGAGTATT
TGTTATCGGGCTATTTATTT

Product: putative formate transporter

Products: NA

Alternate protein names: Formate channel 2 [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRNKLSFDLQLSARKAAIAERIASHKIARSKVSVFLMAMSAGVFMAIGFTFYLSVIADAPSSQALTHLVGGLCFTLGFIL
LAVCGTSLFTSSVMTVMAKSRGVISWRTWLINALLVACGNLAGIACFSLLIWFSGLVMSENAMWGVAVLHCAEGKMHHTF
TESVSLGIMCNLMVCLALWMSYCGRSLCDKIVAMILPITLFVASGFEHCIANLFVIPFAIAIRHFAPRPFGNWRTVAQTI
FRH

Sequences:

>Translated_243_residues
MRNKLSFDLQLSARKAAIAERIASHKIARSKVSVFLMAMSAGVFMAIGFTFYLSVIADAPSSQALTHLVGGLCFTLGFIL
LAVCGTSLFTSSVMTVMAKSRGVISWRTWLINALLVACGNLAGIACFSLLIWFSGLVMSENAMWGVAVLHCAEGKMHHTF
TESVSLGIMCNLMVCLALWMSYCGRSLCDKIVAMILPITLFVASGFEHCIANLFVIPFAIAIRHFAPRPFGNWRTVAQTI
FRH
>Mature_243_residues
MRNKLSFDLQLSARKAAIAERIASHKIARSKVSVFLMAMSAGVFMAIGFTFYLSVIADAPSSQALTHLVGGLCFTLGFIL
LAVCGTSLFTSSVMTVMAKSRGVISWRTWLINALLVACGNLAGIACFSLLIWFSGLVMSENAMWGVAVLHCAEGKMHHTF
TESVSLGIMCNLMVCLALWMSYCGRSLCDKIVAMILPITLFVASGFEHCIANLFVIPFAIAIRHFAPRPFGNWRTVAQTI
FRH

Specific function: Involved in the bidirectional transport of formate [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1788837, Length=230, Percent_Identity=99.1304347826087, Blast_Score=456, Evalue=1e-130,
Organism=Escherichia coli, GI1787132, Length=246, Percent_Identity=48.3739837398374, Blast_Score=223, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6321779, Length=218, Percent_Identity=25.6880733944954, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 26525; Mature: 26525

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS01005 FORMATE_NITRITE_TP_1 ; PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
9.5 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
9.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCC
>Mature Secondary Structure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HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]