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The map label for this gene is yeiQ

Identifier: 218695787

GI number: 218695787

Start: 2481645

End: 2483111

Strand: Direct

Name: yeiQ

Synonym: EC55989_2426

Alternate gene names: 218695787

Gene position: 2481645-2483111 (Clockwise)

Preceding gene: 218695786

Following gene: 218695788

Centisome position: 48.14

GC content: 51.47

Gene sequence:

>1467_bases
ATGAAGACAATTGCCTCCGTTACGCTCCCGCATCATGTACACGCTCCACGCTACGATCGCCAGCAGTTGCAATCACGTAT
CGTTCATTTTGGCTTTGGCGCCTTTCACTGCGCTCATCAGGCGTTACTGACCGATCGTGTGCTGAATGCCCAGGGCGGCG
ACTGGGGGATCTGTGAAATCAGCTTGTTCAGCGGTGATCAACTGATGAGCCAGCTCCGCGCACAGAACCATTTATATACC
GTGCTGGAAAAAGGTGCGGACGGCAATCAGGTGATAATTGTCGGTGCCGTTCACGAATGCCTTAATGCAAAACTGGATTC
CTTAGCGGCAATTATTGAGAAATTTTGCGAGCCACAGGTGGCAATTGTTTCCCTGACGATTACCGAAAAAGGCTATTGTA
TTGACCCGGCCACCGGTGCACTCGACACCAGTAATCCGCGGATTATTCACGATCTACAAACCCCTGAAGAACCTCACTCC
GCACCGGGTATTCTCGTCGAAGCACTGAAACGCCGCCGTGAGCGCGGCCTTACACCGTTTACCGTGCTCTCCTGCGACAA
TATTCCCGACAATGGCCATGTGGTGAAAAACGCGGTGCTGGGAATGGCAGAAAAACGTTCGCCAGAACTCGCCGGGTGGA
TAAAAGAACACGTCAGTTTTCCGGGAACCATGGTCGACCGCATTGTTCCGGCTGCAACCGACGAATCACTGGCAGAAATC
AGCCAGCATCTGGGGGTAAATGATCCCTGCGCGATTAGCTGCGAACCGTTTATCCAGTGGGTGGTGGAAGATAACTTCGT
CGCTGGGCGTCCTGCCTGGGAAGTCGCAGGTGTACAAATGGTGAATGATGTCCTGCCATGGGAAGAGATGAAACTGCGTA
TGCTTAATGGCAGCCACTCTTTTCTCGCTTATCTGGGTTACCTTTCAGGATTCGCCCATATCAGTGATTGCATGCAGGAT
CGCGCATTTCGCCATGCCGCCAGAACATTAATGCTGAATGAGCAAGCGCCGACACTACAAATTAAAGATGTCGATTTAAC
ACAATATGCGGACAAGTTAATTGCACGTTTTGCTAATCCGGCGCTGAAACATAAGACCTGGCAAATCGCAATGGATGGTA
GCCAGAAATTACCGCAACGTATGCTGGCAGGTATTCGCATACATCTGGGGTGCGAAACGGACTGGTCGTTGCTGGCATTA
GGCGTTGCTGGCTGGATGCGTTACGTCAGCGGCGTTGATGATGCCGGAAATGCCATTGATGTTCGCGATCCGCTTAGCGA
TAAAATTCGCGAACTTGTTGCGGGCAGCAGCAGTGAACAACGCGTAACCGCCCTGCTTTCCCTGCGTGAAGTTTTCGGTG
ATGATCTGCCAGATAACCCGCATTTTGTGCAGGCCATCGAACAAGCCTGGCAACAAATCGTACAATTCGGCGCACATCAG
GCGCTATTAAACACCCTCAAAATTTAA

Upstream 100 bases:

>100_bases
CCTCACACTTCATCGCATTAACAATCCAGACCAATTTCAATTGCTGTCATATAACTTTACACTGTCATTGTTAATTTATC
GTTACTAAGACGTGACTCCT

Downstream 100 bases:

>100_bases
CGATTTCTGCGGTTAAAGCGGATGAAGCTCACCTTCGTCCGCTCTCCCCTTCTCTTTTCTGCCTTTTTTAGCCAGGATTA
ACGCTCAGTTAACTTACCAG

Product: putative sugar dehydrogenase, NAD-dependent

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHCAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
APGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQD
RAFRHAARTLMLNEQAPTLQIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGCETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQ
ALLNTLKI

Sequences:

>Translated_488_residues
MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHCAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
APGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQD
RAFRHAARTLMLNEQAPTLQIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGCETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQ
ALLNTLKI
>Mature_488_residues
MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHCAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
APGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQD
RAFRHAARTLMLNEQAPTLQIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGCETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQ
ALLNTLKI

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxuB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=488, Percent_Identity=98.7704918032787, Blast_Score=994, Evalue=0.0,
Organism=Escherichia coli, GI1790779, Length=485, Percent_Identity=56.0824742268041, Blast_Score=554, Evalue=1e-159,
Organism=Escherichia coli, GI1787823, Length=464, Percent_Identity=54.7413793103448, Blast_Score=545, Evalue=1e-156,
Organism=Escherichia coli, GI1790028, Length=234, Percent_Identity=29.9145299145299, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI48994885, Length=317, Percent_Identity=24.2902208201893, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324401, Length=492, Percent_Identity=39.2276422764228, Blast_Score=357, Evalue=2e-99,
Organism=Saccharomyces cerevisiae, GI6320765, Length=492, Percent_Identity=39.2276422764228, Blast_Score=357, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 53896; Mature: 53896

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHCAHQALLTDRVLNAQGGDWGICEI
CCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
SLFSGDQLMSQLRAQNHLYTVLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCE
AIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHSAPGILVEALKRRRERGLTPF
EEEEEEEECCCEEECCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
TVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
EEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHH
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHS
HHHCCCCCCCEECHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHH
FLAYLGYLSGFAHISDCMQDRAFRHAARTLMLNEQAPTLQIKDVDLTQYADKLIARFANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHHCCH
ALKHKTWQIAMDGSQKLPQRMLAGIRIHLGCETDWSLLALGVAGWMRYVSGVDDAGNAID
HHHCCEEEEEECCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
VRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQ
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHH
ALLNTLKI
HHHHHHCC
>Mature Secondary Structure
MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHCAHQALLTDRVLNAQGGDWGICEI
CCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
SLFSGDQLMSQLRAQNHLYTVLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQV
EECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCE
AIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHSAPGILVEALKRRRERGLTPF
EEEEEEEECCCEEECCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
TVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
EEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHH
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHS
HHHCCCCCCCEECHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHH
FLAYLGYLSGFAHISDCMQDRAFRHAARTLMLNEQAPTLQIKDVDLTQYADKLIARFANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHHCCH
ALKHKTWQIAMDGSQKLPQRMLAGIRIHLGCETDWSLLALGVAGWMRYVSGVDDAGNAID
HHHCCEEEEEECCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
VRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQ
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHH
ALLNTLKI
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]