BacMap

Definition	Escherichia coli 55989, complete genome.
Accession	NC_011748
Length	5,154,862

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The map label for this gene is yohF

Identifier: 218695749

GI number: 218695749

Start: 2442009

End: 2442770

Strand: Reverse

Name: yohF

Synonym: EC55989_2388

Alternate gene names: 218695749

Gene position: 2442770-2442009 (Counterclockwise)

Preceding gene: 218695750

Following gene: 218695747

Centisome position: 47.39

GC content: 55.38

Gene sequence:

>762_bases
ATGGCACAGGTTGCGATTATTACCGCCTCCGATTCGGGGATCGGCAAAGAGTGCGCGTTATTACTGGCGCAGCAGGGGTT
TGATATTGGCATTACCTGGCACTCAGATGAAGAAGGGGCAAAAGATACCGCGCGTGAGGTAGTTAGCCACGGCGTACGTG
CGGAGATCGTGCAGCTGGATCTCGGTAAACTGCCAGAAGGTGCGCAGGCGCTGGAGAAACTCATTCAACGGCTGGGGCGT
ATTGATGTGCTGGTGAATAATGCGGGCGCAATGACCAAAGCGCCGTTTCTTGATATGGCTTTCGATGAGTGGCGCAAGAT
TTTTACCGTTGATGTCGATGGTGCATTTTTATGCTCACAAATTGCGGCCCGCCAGATGGTGAAACAAGGGCAGGGCGGTC
ACATCATCAACATTACGTCGGTACATGAACATACGCCGCTGCCGGATGCCAGCGCTTACACAGCCGCTAAACATGCGCTC
GGCGGGTTAACCAAAACGATGGCGCTGGAGCTGGTCAGGCATAAGATTTTGGTGAACGCAGTCGCGCCTGGGGCGATCGC
CACGCCAATGAATGGCATGGATGACAGCGACGTGAAGCCCGACGCGGAGCCTTCGATTCCTCTGCGGCGTTTTGGCGCAA
CGCATGAGATTGCCAGCCTGGTAGCGTGGCTGTGCTCAGAGGGCGCAAATTACACCACCGGGCAGTCGTTGATAGTGGAT
GGCGGCTTTATGTTGGCGAATCCGCAGTTCAACCCAGAATAG

Upstream 100 bases:

>100_bases
GCTTCCATTCAACTCACTGGTGCGTTGGGCGGGGGTTACAAACGCTGATGATATGCGCCTTCTATACTTAACGTTTATTC
AGCGTTAAGTGGAGAACTCG

Downstream 100 bases:

>100_bases
CGCAGTGAGGTGCGTGGTTATTTCAATGGGTAAAATTTTGGTAGGCATGATAAGACGCACAAGCGTCGCATCAGGCATGG
TGCACCGGATGTCGGATGCG

Product: acetoin dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MAQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSHGVRAEIVQLDLGKLPEGAQALEKLIQRLGR
IDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIAARQMVKQGQGGHIINITSVHEHTPLPDASAYTAAKHAL
GGLTKTMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIASLVAWLCSEGANYTTGQSLIVD
GGFMLANPQFNPE

Sequences:

>Translated_253_residues
MAQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSHGVRAEIVQLDLGKLPEGAQALEKLIQRLGR
IDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIAARQMVKQGQGGHIINITSVHEHTPLPDASAYTAAKHAL
GGLTKTMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIASLVAWLCSEGANYTTGQSLIVD
GGFMLANPQFNPE
>Mature_252_residues
AQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSHGVRAEIVQLDLGKLPEGAQALEKLIQRLGRI
DVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIAARQMVKQGQGGHIINITSVHEHTPLPDASAYTAAKHALG
GLTKTMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIASLVAWLCSEGANYTTGQSLIVDG
GFMLANPQFNPE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=31.3008130081301, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=32.4, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=32.520325203252, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI7705925, Length=193, Percent_Identity=35.7512953367876, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=30.241935483871, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=29.6296296296296, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=30.0395256916996, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=27.9527559055118, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=27.8350515463918, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4504505, Length=240, Percent_Identity=27.0833333333333, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=27.3684210526316, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4503301, Length=246, Percent_Identity=24.390243902439, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=28, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=31.3829787234043, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI59889578, Length=181, Percent_Identity=30.3867403314917, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI210032110, Length=169, Percent_Identity=27.2189349112426, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=26.4248704663212, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=27.8688524590164, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40254986, Length=186, Percent_Identity=30.6451612903226, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI7657478, Length=237, Percent_Identity=28.6919831223629, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=26.4248704663212, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI142976729, Length=211, Percent_Identity=23.696682464455, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=98.0237154150198, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=34.2857142857143, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=33.6032388663968, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=29.9180327868852, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=32.5102880658436, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=32.0987654320988, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=31.3492063492063, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=33.6065573770492, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789378, Length=242, Percent_Identity=28.5123966942149, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786812, Length=197, Percent_Identity=31.9796954314721, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=27.3092369477912, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789057, Length=264, Percent_Identity=27.6515151515151, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=31.0077519379845, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=30.3501945525292, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=33.4600760456274, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=33.75, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=33.7448559670782, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=30.6818181818182, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.957528957529, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=30.46875, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=29.0322580645161, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=30.4347826086957, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=28.735632183908, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=29.5880149812734, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=31.6793893129771, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=29.2682926829268, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=29.5019157088123, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=27.8625954198473, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=30, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=31.1111111111111, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=27.2030651340996, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=26.7175572519084, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=28.3018867924528, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=27.9850746268657, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=213, Percent_Identity=32.3943661971831, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=29.5019157088123, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=27.8625954198473, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=190, Percent_Identity=27.8947368421053, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=27.8947368421053, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=188, Percent_Identity=28.1914893617021, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=28.90625, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=209, Percent_Identity=25.3588516746411, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=26.4, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=25, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71997099, Length=203, Percent_Identity=29.5566502463054, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=221, Percent_Identity=28.5067873303167, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=24.6268656716418, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=23.7903225806452, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=26.7015706806283, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=188, Percent_Identity=26.5957446808511, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=203, Percent_Identity=25.1231527093596, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=203, Percent_Identity=25.1231527093596, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=25, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=25.2032520325203, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=233, Percent_Identity=29.1845493562232, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=34.0080971659919, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=30.6451612903226, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=31.6, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=30.7692307692308, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=29.2682926829268, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859837, Length=233, Percent_Identity=31.3304721030043, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=28.3400809716599, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24580925, Length=193, Percent_Identity=32.6424870466321, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=30.3030303030303, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=30.3030303030303, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641232, Length=212, Percent_Identity=29.2452830188679, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24644337, Length=221, Percent_Identity=30.316742081448, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=29.6875, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=29.6875, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571387, Length=199, Percent_Identity=29.6482412060301, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007236, Length=202, Percent_Identity=26.7326732673267, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=25.9842519685039, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24584752, Length=199, Percent_Identity=29.1457286432161, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007238, Length=226, Percent_Identity=25.6637168141593, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647419, Length=190, Percent_Identity=25.2631578947368, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=26.9005847953216, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649181, Length=170, Percent_Identity=25.8823529411765, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357673, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281364494, Length=197, Percent_Identity=25.8883248730964, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26963; Mature: 26832

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSHGVRAEIVQLD
CCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEE
LGKLPEGAQALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQ
CCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHCCEEEEEECCHHHHHHH
IAARQMVKQGQGGHIINITSVHEHTPLPDASAYTAAKHALGGLTKTMALELVRHKILVNA
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIASLVAWLCSEGANYTTGQSLIVD
CCCCCEECCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
GGFMLANPQFNPE
CCEEEECCCCCCC
>Mature Secondary Structure 
AQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSHGVRAEIVQLD
CEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEE
LGKLPEGAQALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQ
CCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHCCEEEEEECCHHHHHHH
IAARQMVKQGQGGHIINITSVHEHTPLPDASAYTAAKHALGGLTKTMALELVRHKILVNA
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIASLVAWLCSEGANYTTGQSLIVD
CCCCCEECCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
GGFMLANPQFNPE
CCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]