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The map label for this gene is fliP

Identifier: 218695553

GI number: 218695553

Start: 2207908

End: 2208645

Strand: Direct

Name: fliP

Synonym: EC55989_2168

Alternate gene names: 218695553

Gene position: 2207908-2208645 (Clockwise)

Preceding gene: 218695552

Following gene: 218695554

Centisome position: 42.83

GC content: 53.25

Gene sequence:

>738_bases
ATGCGTCGTTTATTGTCTGTCGCACCTGTCCTTCTCTGGCTGATTACGCCCCTCGCCTTCGCGCAACTGCCGGGTATCAC
CAGCCAGCCGCTGCCTGGCGGTGGACAAAGCTGGTCGCTCCCGGTGCAGACGCTGGTGTTCATCACCTCGTTGACGTTTA
TTCCGGCAATTTTACTGATGATGACCAGTTTCACCCGCATCATCATTGTTTTTGGTTTATTGCGTAACGCGCTGGGAACA
CCCTCCGCGCCACCTAACCAGGTATTGCTGGGGCTGGCACTGTTTTTGACCTTTTTTATTATGTCACCGGTGATCGACAA
AATTTATGTCGATGCGTACCAGCCATTTAGCGAAGAGAAAATCTCAATGCAGGAGGCGCTGGAAAAAGGGGCGCAGCCGC
TGCGTGAGTTTATGCTGCGTCAGACCCGCGAGGCGGATTTAGGGTTGTTTGCCAGACTGGCGAATACCGGCCCGTTGCAG
GGACCTGAAGCCGTGCCGATGCGCATTTTGCTCCCGGCCTACGTGACCAGCGAGTTGAAAACCGCATTTCAGATAGGCTT
CACGATTTTCATTCCTTTTTTGATTATCGACCTGGTGATTGCCAGCGTGTTGATGGCATTGGGGATGATGATGGTTCCCC
CAGCCACCATTGCTCTGCCCTTTAAACTGATGCTGTTTGTACTGGTGGATGGTTGGCAATTGCTGGTCGGTTCGCTGGCG
CAGAGCTTTTACAGCTAG

Upstream 100 bases:

>100_bases
TGCTGCATAAACTTCCCCCTTCAGCACCAACAGAAGAGATACCGCAGACCGATTTTCAGTCGGTCATGAAAAATTTGCTT
AAGCGTAGCGGGAGATCCTG

Downstream 100 bases:

>100_bases
AGAGGCAAAATGACACCTGAATCGGTCATGATGATGGGGACTGAAGCGATGAAAGTCGCGCTGGCACTGGCTGCCCCGCT
GTTGCTGGTGGCGCTGGTCA

Product: flagellar biosynthesis protein FliP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGT
PSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQ
GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA
QSFYS

Sequences:

>Translated_245_residues
MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGT
PSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQ
GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA
QSFYS
>Mature_245_residues
MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGT
PSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQ
GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA
QSFYS

Specific function: Plays a role in the flagellum-specific transport system

COG id: COG1338

COG function: function code NU; Flagellar biosynthesis pathway, component FliP

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein. Bacterial flagellum basal body (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliP/mopC/spaP family

Homologues:

Organism=Escherichia coli, GI1788259, Length=245, Percent_Identity=100, Blast_Score=476, Evalue=1e-136,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLIP_ECO57 (P0AC06)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   G85812
- PIR:   G90964
- RefSeq:   NP_288409.1
- RefSeq:   NP_310714.1
- ProteinModelPortal:   P0AC06
- EnsemblBacteria:   EBESCT00000025356
- EnsemblBacteria:   EBESCT00000057995
- GeneID:   913785
- GeneID:   961948
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3038
- KEGG:   ecs:ECs2687
- GeneTree:   EBGT00050000009978
- HOGENOM:   HBG414116
- OMA:   MMTGFTR
- ProtClustDB:   PRK05699
- BioCyc:   ECOL83334:ECS2687-MONOMER
- InterPro:   IPR005837
- InterPro:   IPR005838
- PRINTS:   PR00951
- PRINTS:   PR01302
- TIGRFAMs:   TIGR01103

Pfam domain/function: PF00813 FliP

EC number: NA

Molecular weight: Translated: 26929; Mature: 26929

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS01060 FLIP_1; PS01061 FLIP_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15bb3bd0)-; HASH(0x1a8446f0)-; HASH(0x1a8a59a4)-; HASH(0x1a84245c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCH
>Mature Secondary Structure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HHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796