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The map label for this gene is yecS

Identifier: 218695525

GI number: 218695525

Start: 2183736

End: 2184404

Strand: Reverse

Name: yecS

Synonym: EC55989_2139

Alternate gene names: 218695525

Gene position: 2184404-2183736 (Counterclockwise)

Preceding gene: 218695526

Following gene: 218695524

Centisome position: 42.38

GC content: 53.21

Gene sequence:

>669_bases
ATGCAAGAAAGTATACAACTGGTTATTGATTCCTTGCCGTTCCTGCTGAAAGGGGCTGGGTATACGCTGCAACTCAGTAT
CGGCGGCATGTTTTTTGGCTTACTGCTCGGGTTTATTCTCGCGCTGATGCGCCTGTCGCCGATCTGGCCCGTGCGCTGGC
TGGCGCGTTTTTATATCTCTATTTTTCGTGGTACGCCGCTCATCGCACAACTGTTTATGATTTATTACGGCCTGCCGCAG
TTTGGTATCGAATTAGATCCCATTCCGTCAGCAATGATTGGTCTGTCGCTCAACACTGCCGCCTATGCTGCCGAAACGCT
TCGCGCCGCCATTTCTTCTATTGATAAAGGTCAGTGGGAAGCAGCTGCCAGTATTGGTATGACGCCGTGGCAGACCATGC
GTCGCGCGATTTTGCCACAGGCGGCGCGGGTGGCGTTGCCGCCGCTGTCGAACAGCTTTATCAGCCTGGTAAAAGATACG
TCGCTGGCCGCGACAATCCAGGTGCCGGAGCTGTTCCGTCAGGCGCAGTTGATTACCTCGCGCACGCTGGAGGTGTTCAC
CATGTACCTGGCGGCTTCGCTCATCTACTGGATCATGGCGACAGTATTATCGACGTTGCAGAACCATTTTGAGAATCAAC
TTAATCGCCAGGAGAGAGAACCAAAATGA

Upstream 100 bases:

>100_bases
AGAAACGCTTCAAAGATGAAGGGCCGATTCTGTTTATTCATACCGGCGGCGCGCCTGCGCTGTTCGCCTATCATCCCCAC
GTTTAGCTCCGGAAACGCTC

Downstream 100 bases:

>100_bases
GTGCCATTGAAGTTAAGAACCTGGTGAAAAAATTTCACGGTCAGACGGTGCTGCACGGTATCGACCTTGAGGTAAAGCCT
GGCGAAGTGGTGGCAATTAT

Product: putative transporter subunit: permease component of ABC superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQ
FGIELDPIPSAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK

Sequences:

>Translated_222_residues
MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQ
FGIELDPIPSAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK
>Mature_222_residues
MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQ
FGIELDPIPSAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK

Specific function: Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1788226, Length=222, Percent_Identity=100, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI1787030, Length=207, Percent_Identity=36.231884057971, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786873, Length=214, Percent_Identity=37.3831775700935, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787086, Length=221, Percent_Identity=33.4841628959276, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787087, Length=232, Percent_Identity=30.6034482758621, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI87082239, Length=205, Percent_Identity=38.5365853658537, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788645, Length=213, Percent_Identity=34.2723004694836, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1786874, Length=198, Percent_Identity=32.8282828282828, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1788646, Length=199, Percent_Identity=30.1507537688442, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI48994930, Length=171, Percent_Identity=35.0877192982456, Blast_Score=80, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YECS_ECOL6 (P0AFT3)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_754224.1
- ProteinModelPortal:   P0AFT3
- SMR:   P0AFT3
- EnsemblBacteria:   EBESCT00000045551
- GeneID:   1036962
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c2332
- GeneTree:   EBGT00050000008884
- HOGENOM:   HBG704821
- OMA:   RVNRHDL
- ProtClustDB:   PRK15100
- InterPro:   IPR010065
- InterPro:   IPR000515
- TIGRFAMs:   TIGR01726

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 24802; Mature: 24802

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1a518828)-; HASH(0x1a7f41cc)-; HASH(0x1a7582fc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYIS
CCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAYAAETLRAAISSIDKGQWE
HHCCCHHHHHHHHHHHCCCHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHH
AAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDTSLAATIQVPELFRQAQLITS
HHHHCCCCHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCHHHEEEHHHHHHHHHHHHHH
RTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYIS
CCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAYAAETLRAAISSIDKGQWE
HHCCCHHHHHHHHHHHCCCHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHH
AAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDTSLAATIQVPELFRQAQLITS
HHHHCCCCHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCHHHEEEHHHHHHHHHHHHHH
RTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157