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The map label for this gene is flhC

Identifier: 218695457

GI number: 218695457

Start: 2128324

End: 2128902

Strand: Reverse

Name: flhC

Synonym: EC55989_2070

Alternate gene names: 218695457

Gene position: 2128902-2128324 (Counterclockwise)

Preceding gene: 218695458

Following gene: 218695456

Centisome position: 41.3

GC content: 48.7

Gene sequence:

>579_bases
ATGAGTGAAAAAAGCATTGTTCAGGAAGCGCGGGATATTCAGCTGGCAATGGAATTGATCACCCTGGGCGCTCGTTTGCA
GATGCTGGAAAGCGAAACACAGTTAAGTCGCGGACGCCTGATAAAACTTTATAAAGAACTGCGCGGAAGCCCACCGCCGA
AAGGCATGCTGCCATTCTCAACCGACTGGTTTATGACCTGGGAACAAAACGTTCATGCTTCGATGTTCTGTAATGCATGG
CAGTTTTTACTGAAAACCGGTTTGTGTAATGGCGTCGATGCGGTGATCAAAGCCTACCGTTTATACCTTGAACAGTGCCC
ACAAGCAGAAGAAGGACCACTGCTGGCATTAACTCGTGCCTGGACATTGGTGCGGTTTGTTGAAAGTGGATTACTGCAAC
TTTCCAGCTGCAACTGCTGCGGCGGCAATTTTATTACCCACGCTCACCAGCCTGTTGGCAGCTTTGCCTGCAGCTTATGT
CAACCGCCATCCAGGGCAGTAAAAAGACGTAAACTTTCCCAGAATCCTGCCGATATTATCCCACAACTGCTGGATGAACA
GAGAGTACAGGCTGTTTAA

Upstream 100 bases:

>100_bases
ACGATCTCCAGCAAATTCATACCGGCATCATGCTCTCAACACGCTTGCTGAATGATGTTAATCAGCCTGAAGAAGCGCTG
CGCAAGAAAAGGGCCTGATC

Downstream 100 bases:

>100_bases
CTGATACGGTGAGGCGCAACATTCCAGCAGCGGTAACGACGTACCGCTGCTTTTTTTTGCCCCAATCGCGCGTTAACGCC
TGACGACTGAACATCCTGTC

Product: transcriptional activator FlhC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAW
QFLLKTGLCNGVDAVIKAYRLYLEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC
QPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV

Sequences:

>Translated_192_residues
MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAW
QFLLKTGLCNGVDAVIKAYRLYLEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC
QPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV
>Mature_191_residues
SEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAWQ
FLLKTGLCNGVDAVIKAYRLYLEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLCQ
PPSRAVKRRKLSQNPADIIPQLLDEQRVQAV

Specific function: Transcriptional activator. Together with flhD it acts as a compound sigma factor that activates class 2 flagellar genes

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flhC family

Homologues:

Organism=Escherichia coli, GI1788201, Length=192, Percent_Identity=100, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLHC_ECO57 (P0ABY9)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A98954
- PIR:   E85802
- RefSeq:   NP_288328.1
- RefSeq:   NP_310628.1
- ProteinModelPortal:   P0ABY9
- SMR:   P0ABY9
- EnsemblBacteria:   EBESCT00000028872
- EnsemblBacteria:   EBESCT00000056210
- GeneID:   913689
- GeneID:   961863
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2945
- KEGG:   ecs:ECs2601
- GeneTree:   EBGT00050000011112
- HOGENOM:   HBG336392
- OMA:   DWFLTWQ
- ProtClustDB:   PRK12722
- BioCyc:   ECOL83334:ECS2601-MONOMER
- InterPro:   IPR007944
- ProDom:   PD016592

Pfam domain/function: PF05280 FlhC

EC number: NA

Molecular weight: Translated: 21566; Mature: 21435

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLYLEQCPQAEEGPLLALTRA
CCCEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHH
WTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLCQPPSRAVKRRKLSQNPADII
HHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHH
PQLLDEQRVQAV
HHHHHHHHHHCC
>Mature Secondary Structure 
SEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLYLEQCPQAEEGPLLALTRA
CCCEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHH
WTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLCQPPSRAVKRRKLSQNPADII
HHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHH
PQLLDEQRVQAV
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796