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The map label for this gene is argS

Identifier: 218695442

GI number: 218695442

Start: 2111120

End: 2112853

Strand: Direct

Name: argS

Synonym: EC55989_2055

Alternate gene names: 218695442

Gene position: 2111120-2112853 (Clockwise)

Preceding gene: 218695437

Following gene: 218695443

Centisome position: 40.95

GC content: 53.06

Gene sequence:

>1734_bases
GTGAATATTCAGGCTCTTCTCTCAGAAAAAGTCCGTCAGGCCATGATTGCGGCAGGCGCGCCTGCGGATTGCGAACCGCA
GGTTCGTCAGTCAGCAAAAGTTCAGTTCGGCGACTATCAGGCTAACGGCATGATGGCAGTTGCTAAAAAACTGGGTATGG
CACCGCGACAATTAGCAGAGCAGGTGCTGACTCATCTGGATCTTAACGGTATCGCCAGCAAAGTTGAGATCGCCGGTCCA
GGCTTTATCAACATTTTCCTTGATCCGGCATTCCTGGCTGAACATGTTCAGCAGGCGCTGGCGTCCGATCGTCTCGGTGT
TGCTACGCCAGAAAAACAGACCATTGTGGTTGACTACTCTGCGCCAAACGTGGCGAAAGAGATGCACGTCGGTCACCTGC
GCTCTACCATTATTGGTGACGCAGCAGTGCGTACTCTGGAGTTCCTCGGTCACAAAGTGATTCGCGCAAACCACGTCGGC
GACTGGGGCACTCAGTTCGGTATGCTGATTGCATGGCTGGAAAAGCAGCAGCAGGAAAACGCCGGTGAAATGGAGCTGGC
TGACCTTGAAGGTTTCTACCGCGATGCGAAAAAGCATTACGACGAAGATGAAGAGTTTGCCGAGCGTGCACGTAACTACG
TGGTAAAACTGCAAAGCGGTGACGAATATTTCCGCGAGATGTGGCGCAAACTGGTCGACATCACCATGACGCAGAACCAG
ATCACCTACGATCGTCTCAACGTGACGCTGACCCGTGATGACGTGATGGGCGAAAGCCTCTACAACCCGATGCTGCCAGG
AATTGTGGCGGATCTCAAAGCCAAAGGTCTGGCAGTAGAAAGTGAAGGCGCGACCGTCGTATTCCTTGATGAGTTCAAAA
ACAAGGAAGGCGAACCGATGGGCGTGATCATTCAGAAGAAAGATGGCGGCTATCTCTACACCACCACTGATATTGCCTGT
GCGAAATATCGTTATGAAACACTGCATGCCGATCGCGTGCTGTATTACATCGACTCCCGTCAGCATCAACACCTGATGCA
GGCATGGGCGATCGTCCGTAAAGCAGGCTATGTACCGGAATCCGTACCGCTGGAACACCACATGTTCGGCATGATGCTGG
GTAAAGACGGCAAACCGTTCAAAACCCGCGCGGGTGGTACAGTGAAACTGGCCGATCTGCTGGATGAAGCCCTGGAACGT
GCACGCCGTCTGGTGGCAGAAAAGAACCCGGATATGCCAGCTGACGAGCTGGAAAAACTGGCTAACTCGGTTGGTATTGG
TGCGGTGAAATATGCGGATCTCTCCAAAAACCGCACCACGGACTACATCTTCGACTGGGACAACATGCTGGCGTTTGAGG
GTAATACCGCGCCATACATGCAGTATGCTTACACGCGTGTATTGTCCGTGTTCCGTAAGGCAGAAATTAACGAAGAGCAA
CTGGCTGCAGCTCCGGTAATCATCCGTGAAGATCGTGAAGCGCAACTGGCAGCTCGCCTGCTGCAGTTTGAAGAAACCCT
CACCGTGGTTGCCCGTGAAGGCACGCCGCATGTGATGTGTGCTTACCTGTACGATCTGGCTGGTCTGTTCTCTGGCTTCT
ACGAGCACTGCCCGATCCTCAGCGCAGAAAACGAAGAAGTGCGTAACAGCCGTCTGAAACTGGCACAACTGACAGCGAAG
ACGCTAAAGCTGGGTCTGGATACGCTGGGTATTGAGACAGTAGAGCGTATGTAA

Upstream 100 bases:

>100_bases
ACGTTGCTGACGAAAACAGCCATTTGCAGTATACTCCCGCCCTAATTTCTTTAACTGGTGCGGGCAATTTTTGCTCGCTT
CATCAATGTAAGGTATTCCG

Downstream 100 bases:

>100_bases
TCGATTTTTCGTGAGAGTAAAGCCTGATCAGGGTTACCTGATCAGGCTTTTTTATTGCCATCTAAATGTATTCTGAAAAT
GGACATGCCATTGTTTTCTC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGP
GFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
DWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMPADELEKLANSVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEINEEQ
LAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAK
TLKLGLDTLGIETVERM

Sequences:

>Translated_577_residues
MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGP
GFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
DWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMPADELEKLANSVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEINEEQ
LAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAK
TLKLGLDTLGIETVERM
>Mature_577_residues
MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGP
GFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
DWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQ
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMPADELEKLANSVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEINEEQ
LAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAK
TLKLGLDTLGIETVERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=599, Percent_Identity=38.7312186978297, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI197100773, Length=537, Percent_Identity=29.4227188081937, Blast_Score=200, Evalue=3e-51,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=99.6533795493934, Blast_Score=1193, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=600, Percent_Identity=37.1666666666667, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71985068, Length=564, Percent_Identity=37.7659574468085, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17532153, Length=384, Percent_Identity=27.6041666666667, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320548, Length=544, Percent_Identity=34.375, Blast_Score=258, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6321883, Length=538, Percent_Identity=28.8104089219331, Blast_Score=213, Evalue=8e-56,
Organism=Drosophila melanogaster, GI18859963, Length=600, Percent_Identity=37.8333333333333, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI28571570, Length=478, Percent_Identity=29.0794979079498, Blast_Score=168, Evalue=8e-42,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64699; Mature: 64699

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHH
QVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYS
HHHHHCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
APNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCC
AGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQ
CCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCHHHHHHHHHHHHHEEECCCE
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPM
EEEEEEEEEEECCHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPE
EEEEEECCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKL
CCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ANSVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEINEEQ
HHHCCCCEEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHH
LAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPIL
HHHCCEEEECCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
SAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
>Mature Secondary Structure
MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHH
QVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYS
HHHHHCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
APNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQEN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCC
AGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQ
CCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCHHHHHHHHHHHHHEEECCCE
ITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPM
EEEEEEEEEEECCHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPE
EEEEEECCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKL
CCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ANSVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEINEEQ
HHHCCCCEEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHH
LAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPIL
HHHCCEEEECCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
SAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA