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The map label for this gene is ydjJ

Identifier: 218695333

GI number: 218695333

Start: 2006221

End: 2007198

Strand: Reverse

Name: ydjJ

Synonym: EC55989_1943

Alternate gene names: 218695333

Gene position: 2007198-2006221 (Counterclockwise)

Preceding gene: 218695334

Following gene: 218695332

Centisome position: 38.94

GC content: 47.14

Gene sequence:

>978_bases
GTGCCTAAAGAAGATGAAGTTTTGATTAAAGTAGAATATGTCGGTATTTGTGGTTCAGATGTACATGGTTTTGAATCAGG
CCCGTTTATTCCGCCTAAAGACCCAAATCAAGAAATTGGCCTGGGTCATGAATGCGCCGGGACGGTTGTGGCTGTGGGAA
GCCGCGTGCGCAAATTTAAACCGGGGGATCGGGTAAATATCGAACCTGGCGTTCCTTGCGGTCACTGTCGTTACTGTCTG
GAAGGCAAATATAACATCTGCCCGGACGTTGATTTTATGGCGACACAACCCAACTACCGCGGCGCATTAACGCACTATCT
GTGTCATCCGGAGAGCTTTACTTACAAACTGCCAGACAATATGGACACGATGGAAGGGGCGCTGGTGGAGCCTGCCGCAG
TCGGGATGCATGCCGCGATGCTGGCAGATGTTAAACCGGGTAAGAAGATAATTATTCTGGGAGCAGGTTGTATTGGTTTG
ATGACGTTGCAAGCGTGCAAATGCCTGGGCGCAACGGAAATTGCCGTCGTTGATGTGCTGGAAAAACGTCTGATAATGGC
GGAACAACTTGGTGCGACAGTGGTTATTAACGGCACAAAAGAAGACACTATTGCACGCTGTCAGCAATTTACCGAAGACA
TGGGCGCAGATATTGTTTTCGAAACAGCGGGTTCTGCGGTCACCGTTAAACAGGCACCTTATCTGGTAATGCGCGGCGGT
AAAATTATGATTGTTGGTACTGTACCCGGCGATTCGGCAATCAATTTCCTCAAAATCAATCGCGAAGTCACTATCCAGAC
GGTATTCCGCTATGCCAATCGTTATCCGGTCACGATTGAAGCTATTTCTTCAGGGCGATTCGATGTGAAATCGATGGTGA
CGCATATTTACGATTATCGGGATGTACAACAGGCATTTGAAGAGTCAGTTAACAACAAACGCGACATTATTAAAGGCGTT
ATTAAAATTAGCGATTAA

Upstream 100 bases:

>100_bases
TGCAGTAGCCAATAAATAATACGGGTGGATTCAAAATGAAAAATTCAAAAGCAATATTGCAGGTGCCGGGCACAATGAAA
TTTTTTCAGCAGAAATACCA

Downstream 100 bases:

>100_bases
TTAATACGGGAGAACAGAACATGCTCGCAGATATCAGATATTGGGAAAACGATGCCACAAATAAACATTATGCAATTGCC
CATTTTAACGTATGGAATGC

Product: putative iditol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCL
EGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCIGL
MTLQACKCLGATEIAVVDVLEKRLIMAEQLGATVVINGTKEDTIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMRGG
KIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNNKRDIIKGV
IKISD

Sequences:

>Translated_325_residues
MPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCL
EGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCIGL
MTLQACKCLGATEIAVVDVLEKRLIMAEQLGATVVINGTKEDTIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMRGG
KIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNNKRDIIKGV
IKISD
>Mature_324_residues
PKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLE
GKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCIGLM
TLQACKCLGATEIAVVDVLEKRLIMAEQLGATVVINGTKEDTIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMRGGK
IMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNNKRDIIKGVI
KISD

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=312, Percent_Identity=39.7435897435897, Blast_Score=212, Evalue=3e-55,
Organism=Homo sapiens, GI4501929, Length=338, Percent_Identity=26.9230769230769, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI34577061, Length=337, Percent_Identity=26.4094955489614, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4501933, Length=341, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI156523966, Length=342, Percent_Identity=26.9005847953216, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4501939, Length=342, Percent_Identity=26.9005847953216, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI71743840, Length=336, Percent_Identity=25.8928571428571, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI262073058, Length=336, Percent_Identity=25.8928571428571, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI71565154, Length=356, Percent_Identity=25.561797752809, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1788073, Length=325, Percent_Identity=99.0769230769231, Blast_Score=665, Evalue=0.0,
Organism=Escherichia coli, GI1790045, Length=306, Percent_Identity=29.4117647058824, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788407, Length=320, Percent_Identity=29.6875, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1790718, Length=308, Percent_Identity=29.5454545454545, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788075, Length=324, Percent_Identity=28.3950617283951, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI226510992, Length=327, Percent_Identity=28.1345565749235, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787863, Length=328, Percent_Identity=26.8292682926829, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87082125, Length=252, Percent_Identity=31.3492063492063, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI87081918, Length=259, Percent_Identity=30.1158301158301, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786552, Length=343, Percent_Identity=28.2798833819242, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562876, Length=328, Percent_Identity=36.890243902439, Blast_Score=217, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI17562878, Length=323, Percent_Identity=37.4613003095975, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71988145, Length=248, Percent_Identity=30.6451612903226, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25146526, Length=358, Percent_Identity=23.463687150838, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562584, Length=261, Percent_Identity=29.8850574712644, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323099, Length=329, Percent_Identity=37.3860182370821, Blast_Score=202, Evalue=7e-53,
Organism=Saccharomyces cerevisiae, GI6322619, Length=325, Percent_Identity=35.0769230769231, Blast_Score=190, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6319955, Length=325, Percent_Identity=35.0769230769231, Blast_Score=189, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6319257, Length=353, Percent_Identity=30.028328611898, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319258, Length=349, Percent_Identity=27.7936962750716, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6320033, Length=363, Percent_Identity=27.5482093663912, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319621, Length=310, Percent_Identity=29.0322580645161, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323729, Length=274, Percent_Identity=27.3722627737226, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=286, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=285, Percent_Identity=27.0175438596491, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17137530, Length=330, Percent_Identity=40.9090909090909, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI17737897, Length=330, Percent_Identity=39.3939393939394, Blast_Score=217, Evalue=9e-57,
Organism=Drosophila melanogaster, GI221457811, Length=313, Percent_Identity=27.1565495207668, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI45550770, Length=313, Percent_Identity=27.1565495207668, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI45551930, Length=313, Percent_Identity=27.1565495207668, Blast_Score=114, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35454; Mature: 35322

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00059 ADH_ZINC ; PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKFK
CCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDN
CCCEEECCCCCCHHHHHHEECCCCCCCCCCCEEECCCCCCCCCEEEEECCCCEEEECCCC
MDTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVL
CCCCCCCCCCHHHHHHHHHHHEECCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHH
EKRLIMAEQLGATVVINGTKEDTIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMRGG
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCEEEEECC
KIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYR
EEEEEEECCCCCCEEEEEECCEEEHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHH
DVQQAFEESVNNKRDIIKGVIKISD
HHHHHHHHHCCCHHHHHEEEEEECC
>Mature Secondary Structure 
PKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKFK
CCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDN
CCCEEECCCCCCHHHHHHEECCCCCCCCCCCEEECCCCCCCCCEEEEECCCCEEEECCCC
MDTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVL
CCCCCCCCCCHHHHHHHHHHHEECCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHH
EKRLIMAEQLGATVVINGTKEDTIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMRGG
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCEEEEECC
KIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYR
EEEEEEECCCCCCEEEEEECCEEEHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHH
DVQQAFEESVNNKRDIIKGVIKISD
HHHHHHHHHCCCHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]