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The map label for this gene is fabZ

Identifier: 218693645

GI number: 218693645

Start: 201366

End: 201821

Strand: Direct

Name: fabZ

Synonym: EC55989_0174

Alternate gene names: 218693645

Gene position: 201366-201821 (Clockwise)

Preceding gene: 218693644

Following gene: 218693646

Centisome position: 3.91

GC content: 50.22

Gene sequence:

>456_bases
TTGACTACTAACACTCATACTCTGCAGATTGAAGAGATTTTAGAACTTCTGCCGCACCGTTTCCCGTTCTTACTGGTGGA
TCGCGTGCTGGATTTTGAAGAAGGTCGTTTTCTGCGCGCAGTAAAAAATGTCTCTGTCAATGAGCCATTCTTCCAGGGCC
ATTTCCCTGGAAAACCGATTTTCCCGGGTGTGCTGATTCTGGAAGCAATGGCACAGGCAACAGGTATTCTGGCGTTTAAA
AGCGTAGGAAAACTGGAACCGGGTGAACTGTACTACTTCGCTGGTATTGACGAAGCGCGCTTCAAGCGCCCGGTCGTGCC
TGGCGATCAAATGATCATGGAAGTCACTTTCGAAAAAACGCGCCGCGGCCTGACCCGTTTTAAAGGGGTTGCTCTGGTCG
ATGGTAAAGTAGTTTGCGAAGCAACGATGATGTGTGCTCGTAGCCGGGAGGCCTGA

Upstream 100 bases:

>100_bases
CCATCTTTTGTTCGCCAAACTTTACGGCCTGTCTCATTCTTACGATTGCGGCAGGCCGTGTTATTATTGTCGTTTCTTAT
ATTTTGACAGGAAGAGTATC

Downstream 100 bases:

>100_bases
TAAGTGATTGATAAATCCGCCTTTGTGCATCCAACCGCCATTGTGGAAGAGGGCGCGTCAATTGGCGCGAACGCACACAT
TGGTCCTTTTTGTATCGTTG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFK
SVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA

Sequences:

>Translated_151_residues
MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFK
SVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
>Mature_150_residues
TTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKS
VGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=151, Percent_Identity=100, Blast_Score=307, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_ECO24 (A7ZHS0)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001461349.1
- ProteinModelPortal:   A7ZHS0
- SMR:   A7ZHS0
- STRING:   A7ZHS0
- EnsemblBacteria:   EBESCT00000021963
- GeneID:   5590406
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_0184
- eggNOG:   COG0764
- GeneTree:   EBGT00050000010796
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   ECOL331111:ECE24377A_0184-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17033; Mature: 16902

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: ACT_SITE 54-54

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPI
CCCCCCEEEHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCEECCCCCCCCC
FPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKT
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHH
RRGLTRFKGVALVDGKVVCEATMMCARSREA
HHHHHHHCCEEEECCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPI
CCCCCEEEHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCEECCCCCCCCC
FPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKT
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHH
RRGLTRFKGVALVDGKVVCEATMMCARSREA
HHHHHHHCCEEEECCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA