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The map label for this gene is yadR

Identifier: 218693622

GI number: 218693622

Start: 176588

End: 176932

Strand: Direct

Name: yadR

Synonym: EC55989_0151

Alternate gene names: 218693622

Gene position: 176588-176932 (Clockwise)

Preceding gene: 218693621

Following gene: 218693626

Centisome position: 3.43

GC content: 51.59

Gene sequence:

>345_bases
ATGAGTGATGACGTAGCACTGCCGCTGGAGTTTACCGACGCAGCAGCCAACAAAGTTAAAAGCCTGATCGCTGACGAAGA
TAACCCGAATCTGAAATTACGCGTGTATATCACCGGTGGCGGTTGCAGCGGCTTCCAGTATGGTTTCACCTTTGATGATC
AGGTGAACGAAGGCGATATGACCATCGAAAAACAGGGCGTTGGCCTGGTGGTTGATCCGATGAGCCTGCAATATCTGGTC
GGCGGTTCCGTTGACTACACCGAAGGACTGGAAGGTTCTCGTTTCATCGTGACCAACCCGAACGCGAAAAGCACCTGCGG
TTGCGGTTCTTCCTTTAGCATCTAA

Upstream 100 bases:

>100_bases
AGCCAGCGAGAATACTTGAACGAAATACCAGGGTATTAGATAATGGCGATTATTATTGGGTTAGAATTTGCCCAATTGCC
GATGTCGTTTGGAGCAAAAT

Downstream 100 bases:

>100_bases
TCTGTTGTTCATGTGCCGGATAAACTATCCGGCACATCTTCTCTCTTCAACGCCCATTCTCATCCAGCGCAAACGTCGGT
AGCTTAAGATGCCAACGAAT

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 113

Protein sequence:

>114_residues
MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLV
GGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI

Sequences:

>Translated_114_residues
MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLV
GGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
>Mature_113_residues
SDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVG
GSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=83, Percent_Identity=46.9879518072289, Blast_Score=80, Evalue=4e-16,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=33.0188679245283, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786351, Length=114, Percent_Identity=100, Blast_Score=233, Evalue=3e-63,
Organism=Escherichia coli, GI1788877, Length=110, Percent_Identity=40, Blast_Score=74, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=40.7407407407407, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193209025, Length=107, Percent_Identity=31.7757009345794, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25146411, Length=107, Percent_Identity=31.7757009345794, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=32.0754716981132, Blast_Score=71, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24649697, Length=109, Percent_Identity=39.4495412844037, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24642263, Length=107, Percent_Identity=34.5794392523364, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12101; Mature: 11969

Theoretical pI: Translated: 3.90; Mature: 3.90

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDM
CCCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCEECCCCCCCCE
TIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
EEECCCCEEEECCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDM
CCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCEECCCCCCCCE
TIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
EEECCCCEEEECCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]