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The map label for this gene is idnK

Identifier: 218692654

GI number: 218692654

Start: 5063857

End: 5064420

Strand: Direct

Name: idnK

Synonym: ECED1_5122

Alternate gene names: 218692654

Gene position: 5063857-5064420 (Clockwise)

Preceding gene: 218692649

Following gene: 218692657

Centisome position: 97.2

GC content: 43.62

Gene sequence:

>564_bases
ATGGCGGGTGAAAGCTTTATTTTGATGGGCGTATCAGGGAGTGGTAAAACATTAATTGGTAGCAAGGTTGCCGCGTTATT
GTCTGCGAAATTTATTGATGGTGACGATCTTCATCCAGCCAAAAATATAGATAAAATGTCGCAAGGCATTCCATTATCTG
ATGAAGATCGACTTCCCTGGCTGGAACGCTTAAATGATGCTTCATACAGTCTTTATAAAAAGAATGAAACAGGATTTATT
GTCTGTTCATCATTAAAAAAACAGTATCGTGATATTTTACGCAAGGGTAGCCCCCATGTTCATTTCCTCTGGTTAGATGG
CGATTATGAAACTATTCTCGCGCGAATGCAGCGTCGGGCTGGGCATTTTATGCCGGTAGCGTTACTAAAAAGTCAGTTTG
AGGCGCTGGAGCGTCCACAAGCAGATGAACAGGATATTGTGCGCATTGATATCAACCATGATATTGCCAATGTCACCGAA
CAATGTCGGCAGGCTGTGCTGGCGATAAGACAAAACAGAATATGTGCGAAAGAGGGCAGCGCCTCAGATCAGCGCTGCGA
ATGA

Upstream 100 bases:

>100_bases
ATGTGCCTTGTAATTCTTATCAACAGAAATAAAAAAACGTGAAATTATTATGCCGCCAGGCGTAGTATCGCCGCAGGTAA
GATGATTCAGGAGATTTTAA

Downstream 100 bases:

>100_bases
TTTTCAAAAATCTGCTTTCAACACCACGCGGTAGCGCGCTTTACCATCGCGCACATGCTGGATGGCGTCGTTAATTTTCG
ACATCGGGAACAGTTCGGTA

Product: D-gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase 1

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFI
VCSSLKKQYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTE
QCRQAVLAIRQNRICAKEGSASDQRCE

Sequences:

>Translated_187_residues
MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFI
VCSSLKKQYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTE
QCRQAVLAIRQNRICAKEGSASDQRCE
>Mature_186_residues
AGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFIV
CSSLKKQYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQ
CRQAVLAIRQNRICAKEGSASDQRCE

Specific function: Gluconate utilization system GNT-II. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family

Homologues:

Organism=Homo sapiens, GI299758445, Length=172, Percent_Identity=39.5348837209302, Blast_Score=130, Evalue=5e-31,
Organism=Escherichia coli, GI1790719, Length=187, Percent_Identity=100, Blast_Score=389, Evalue=1e-110,
Organism=Escherichia coli, GI87082265, Length=161, Percent_Identity=47.2049689440994, Blast_Score=178, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI25146487, Length=156, Percent_Identity=39.7435897435897, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6320454, Length=158, Percent_Identity=37.3417721518987, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IDNK_ECOLI (P39208)

Other databases:

- EMBL:   U14003
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   M96355
- PIR:   S56494
- RefSeq:   AP_004764.1
- RefSeq:   NP_418689.1
- ProteinModelPortal:   P39208
- SMR:   P39208
- STRING:   P39208
- EnsemblBacteria:   EBESCT00000003873
- EnsemblBacteria:   EBESCT00000015004
- GeneID:   946066
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW4225
- KEGG:   eco:b4268
- EchoBASE:   EB2072
- EcoGene:   EG12152
- eggNOG:   COG3265
- GeneTree:   EBGT00050000009755
- HOGENOM:   HBG335815
- OMA:   AGCGKSC
- ProtClustDB:   PRK09825
- BioCyc:   EcoCyc:GLUCONOKINI-MONOMER
- BioCyc:   MetaCyc:GLUCONOKINI-MONOMER
- Genevestigator:   P39208
- InterPro:   IPR000623
- InterPro:   IPR006001
- TIGRFAMs:   TIGR01313

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.12

Molecular weight: Translated: 21004; Mature: 20873

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPW
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCH
LERLNDASYSLYKKNETGFIVCSSLKKQYRDILRKGSPHVHFLWLDGDYETILARMQRRA
HHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHC
GHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQCRQAVLAIRQNRICAKEGS
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
ASDQRCE
CCCCCCC
>Mature Secondary Structure 
AGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPW
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCH
LERLNDASYSLYKKNETGFIVCSSLKKQYRDILRKGSPHVHFLWLDGDYETILARMQRRA
HHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHC
GHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQCRQAVLAIRQNRICAKEGS
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
ASDQRCE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018