Click here to switch to the map view.

The map label for this gene is yjcC [H]

Identifier: 218692351

GI number: 218692351

Start: 4746787

End: 4748373

Strand: Direct

Name: yjcC [H]

Synonym: ECED1_4786

Alternate gene names: 218692351

Gene position: 4746787-4748373 (Clockwise)

Preceding gene: 218692349

Following gene: 218692353

Centisome position: 91.12

GC content: 44.68

Gene sequence:

>1587_bases
ATGAGTCATCGTGCACGACACCAATTACTGGCGTTTCCGGGCATTATCTTTTTAGTTCTCTTTCCCATCATTCTGTCGCT
ATGGATTGCCTTCTTTTGGGCAAAATCAGAAGTGAATAATCAGCTCCGAACCTTTGCTCAGCTGGCGTTGGATAAATCTG
AGCTGGTCATTCGTCAGGCAGATTTAGTGAGCGATGCAGCTGAACGCTATCAGGGGCAAGTTTGCACTCCAGCCCATCAA
AAGCGAATGTTGAATATTATTCGTGGCTATCTTTATATTAATGAATTGATTTATGCTCGTGATAACCATTTTTTATGCTC
ATCGCTGATAGCGTCTGTAAATGGCTATACGATTGCACCGGCCGATTATAAGCGCGAACCTAACGTTTCTATCTATTATT
ACCGTGATACGCCTTTTTTCTCTGGCTATAAAATGACCTACATGCAGCGGGGAAATTATGTGGCGGTTATCAACCCTCTC
TTCTGGAGTGAAGTGATGTCTGATGATCCGACATTGCAATGGGGAGTGTATGATACGGTGACGAAAACCTTTTTCTCGTT
AAGCAACGAGGCCTCGGCAGCAACGTTTTCTCCGCTGATTCATTTGAATGATTTAACCGTACAACGAAATGGCTATTTAT
ATGCGACAGTTTATTCGACAAAACGCCCAATTGCAGCCATTGTTGCGACTTCATATCAACGTCTTATAACTCATTTTTAT
AATCATCTTATTTTTGCGTTGCCCGCCGGTATTTTGGGGAGTCTTGTTCTGCTATTACTCTGGCTACGTATTCGACAAAA
CTATTTGTCTCCCAAACGCAAATTGCAACGCGCCCTCGAAAAACATCAACTTTGCCTTTATTACCAGCCAATAATCGATA
TCAAAACAGAAAAATGTATCGGCGCTGAAGCGTTGTTACGTTGGCCTGGTGAGCAGGGGCAAGTAATGAATCCGGCAGAG
TTTATTCCGCTGGCAGAAAAGGAGGGGATGATCGAACAGGTAACTGATTATGTTATTGATAATGTCTTCCGTGATTTGGG
CGCGTATCTGGCAACACATACCGATCGCTATGTTTCTATTAACCTGTCAGCCTCCGATTTTCATACCTCACGGTTGATAG
CGCGAACCAATCAGAAAACAGAGCAACATGCGGTGCGTCCGCAGCAAATTAAATTTGAAGTGACTGAACATGCATTTCTT
GATGTCGACAAAATGACGCCGATTATTCTGGCTTTCCGCAAGGCCGGTTACGAAGTGGCAATTGATGATTTTGGTATTGG
CTACTCTAACTTGCATAACCTTAAATCATTGAATGTCGATATTTTGAAAATCGATAAATCGTTTGTTGAGACGCTGACCA
CCCACAAAACCAGTCATTTGATTGCGGAACACATCATCGAGCTGGCGCACAGCCTGGGATTAAAAACGATCGCTGAAGGT
GTCGAAACTGAGGCGCAGGTTAACTGGCTGCGCAAACGCGGCGTGCGCTATTGCCAGGGATGGTTCTTCGCGAAGGCGAT
GCCGCCGCAGGTGTTTATGCAATGGATGGAGCAATTACCCGCGCGGGAGTTAACGCGCGGGCAATAA

Upstream 100 bases:

>100_bases
GCAAAAGTGCTATTTATACCGTAAGATTTATCTAAAGACGTCGGTAGCCAGGGTTTCACCTTGCAATAACCGGGTATAAA
CAGGCAGGGAATTGATAGCA

Downstream 100 bases:

>100_bases
AACTACAGGCGGTGGCGATAATCGCTGGGAGTGCGATCAAACTGCCGACGGAAAACGCGGGAGAAGGTCTGCTGAGAGAC
ATAACCCAGGTCCATTGCGA

Product: putative signal transduction protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MSHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQ
KRMLNIIRGYLYINELIYARDNHFLCSSLIASVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPL
FWSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLITHFY
NHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMNPAE
FIPLAEKEGMIEQVTDYVIDNVFRDLGAYLATHTDRYVSINLSASDFHTSRLIARTNQKTEQHAVRPQQIKFEVTEHAFL
DVDKMTPIILAFRKAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEG
VETEAQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ

Sequences:

>Translated_528_residues
MSHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQ
KRMLNIIRGYLYINELIYARDNHFLCSSLIASVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPL
FWSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLITHFY
NHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMNPAE
FIPLAEKEGMIEQVTDYVIDNVFRDLGAYLATHTDRYVSINLSASDFHTSRLIARTNQKTEQHAVRPQQIKFEVTEHAFL
DVDKMTPIILAFRKAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEG
VETEAQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ
>Mature_527_residues
SHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQK
RMLNIIRGYLYINELIYARDNHFLCSSLIASVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPLF
WSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLITHFYN
HLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMNPAEF
IPLAEKEGMIEQVTDYVIDNVFRDLGAYLATHTDRYVSINLSASDFHTSRLIARTNQKTEQHAVRPQQIKFEVTEHAFLD
VDKMTPIILAFRKAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEGV
ETEAQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=528, Percent_Identity=97.5378787878788, Blast_Score=1051, Evalue=0.0,
Organism=Escherichia coli, GI87081743, Length=528, Percent_Identity=33.3333333333333, Blast_Score=295, Evalue=6e-81,
Organism=Escherichia coli, GI87081980, Length=259, Percent_Identity=34.7490347490347, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI226510982, Length=251, Percent_Identity=38.2470119521912, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788502, Length=286, Percent_Identity=29.020979020979, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI87081845, Length=279, Percent_Identity=31.5412186379928, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081921, Length=244, Percent_Identity=36.0655737704918, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1787541, Length=249, Percent_Identity=32.1285140562249, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788849, Length=236, Percent_Identity=30.0847457627119, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1786507, Length=242, Percent_Identity=30.5785123966942, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787055, Length=254, Percent_Identity=31.1023622047244, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082096, Length=235, Percent_Identity=30.6382978723404, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1787410, Length=225, Percent_Identity=27.5555555555556, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 60694; Mature: 60563

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
DLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDNHFLCSSLIASVNGYTIAP
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEECC
ADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPLFWSEVMSDDPTLQWGVYDTV
CCCCCCCCCEEEEEECCCCCCCEEEEEEECCCEEEEECHHHHHHHHCCCCCEEECHHHHH
TKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLITHFY
HHHHHHHCCCCCCHHHCCEEEEECEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
NHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCHHCCCCCHHC
GAEALLRWPGEQGQVMNPAEFIPLAEKEGMIEQVTDYVIDNVFRDLGAYLATHTDRYVSI
CHHHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
NLSASDFHTSRLIARTNQKTEQHAVRPQQIKFEVTEHAFLDVDKMTPIILAFRKAGYEVA
EECCCHHHHHHHHHHCCCHHHHHCCCCHHEEEEEHHHHHEEHHHCCHHHHHHHHCCCEEE
IDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEG
EECCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
VETEAQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ
CCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure 
SHRARHQLLAFPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
DLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDNHFLCSSLIASVNGYTIAP
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEECC
ADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPLFWSEVMSDDPTLQWGVYDTV
CCCCCCCCCEEEEEECCCCCCCEEEEEEECCCEEEEECHHHHHHHHCCCCCEEECHHHHH
TKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLITHFY
HHHHHHHCCCCCCHHHCCEEEEECEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
NHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCHHCCCCCHHC
GAEALLRWPGEQGQVMNPAEFIPLAEKEGMIEQVTDYVIDNVFRDLGAYLATHTDRYVSI
CHHHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
NLSASDFHTSRLIARTNQKTEQHAVRPQQIKFEVTEHAFLDVDKMTPIILAFRKAGYEVA
EECCCHHHHHHHHHHCCCHHHHHCCCCHHEEEEEHHHHHEEHHHCCHHHHHHHHCCCEEE
IDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEG
EECCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
VETEAQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ
CCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]