Click here to switch to the map view.

The map label for this gene is nusG [H]

Identifier: 218692263

GI number: 218692263

Start: 4638094

End: 4638639

Strand: Direct

Name: nusG [H]

Synonym: ECED1_4689

Alternate gene names: 218692263

Gene position: 4638094-4638639 (Clockwise)

Preceding gene: 218692262

Following gene: 218692264

Centisome position: 89.03

GC content: 51.28

Gene sequence:

>546_bases
ATGTCTGAAGCTCCTAAAAAGCGCTGGTACGTCGTTCAGGCGTTTTCCGGTTTTGAAGGCCGCGTAGCAACGTCGCTGCG
TGAGCATATCAAATTACACAACATGGAAGAGTTGTTTGGTGAAGTCATGGTACCAACCGAAGAAGTGGTTGAAATCCGTG
GCGGTCAGCGTCGCAAAAGCGAACGTAAATTCTTCCCTGGCTACGTCCTCGTTCAGATGGTGATGAACGACGCGAGCTGG
CACCTGGTGCGCAGCGTACCGCGTGTGATGGGCTTCATCGGCGGTACTTCCGATCGTCCTGCGCCAATCAGCGATAAAGA
AGTCGATGCGATTATGAACCGCCTGCAGCAGGTTGGTGATAAGCCGCGTCCGAAAACGTTGTTTGAACCGGGTGAAATGG
TCCGTGTTAATGATGGTCCGTTCGCTGACTTCAACGGCGTTGTTGAAGAAGTTGATTACGAGAAATCTCGTCTGAAAGTG
TCTGTTTCTATCTTCGGTCGTGCGACCCCTGTAGAGCTGGACTTCAGCCAGGTTGAAAAAGCTTAA

Upstream 100 bases:

>100_bases
ATTGTGGCTGCGGTTACCGCAGTAATGTCACTGATCCTGTGGGGACTGGATGGTATTCTGGTTCGCCTGGTATCCTTTAT
CACTGGCCTGAGGTTCTGAG

Downstream 100 bases:

>100_bases
CCCAGCGATCAAAAAAGCGGCGATTTAATCGTTGCACAAGGCGCGAGATTGGAATACAATTTCGCGCCTTTTGTTTTTAT
GGGCCTTGCCCGTAAAACGA

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEELFGEVMVPTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASW
HLVRSVPRVMGFIGGTSDRPAPISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
SVSIFGRATPVELDFSQVEKA

Sequences:

>Translated_181_residues
MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEELFGEVMVPTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASW
HLVRSVPRVMGFIGGTSDRPAPISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
SVSIFGRATPVELDFSQVEKA
>Mature_180_residues
SEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEELFGEVMVPTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWH
LVRSVPRVMGFIGGTSDRPAPISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKVS
VSIFGRATPVELDFSQVEKA

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=181, Percent_Identity=99.4475138121547, Blast_Score=366, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 20546; Mature: 20415

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEELFGEVMVPTEEVVEIRGGQRRKS
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHCCCCCCCC
ERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAPISDKEVDAIMNRLQQVGD
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
KPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKVSVSIFGRATPVELDFSQVEK
CCCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCHHEEEEEEEECCCCCCEECHHHHCC
A
C
>Mature Secondary Structure 
SEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEELFGEVMVPTEEVVEIRGGQRRKS
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHCCCCCCCC
ERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAPISDKEVDAIMNRLQQVGD
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
KPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKVSVSIFGRATPVELDFSQVEK
CCCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCHHEEEEEEEECCCCCCEECHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]