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The map label for this gene is trkH [H]

Identifier: 218692141

GI number: 218692141

Start: 4490020

End: 4491471

Strand: Direct

Name: trkH [H]

Synonym: ECED1_4551

Alternate gene names: 218692141

Gene position: 4490020-4491471 (Clockwise)

Preceding gene: 218692140

Following gene: 218692142

Centisome position: 86.19

GC content: 52.82

Gene sequence:

>1452_bases
ATGCATTTTCGCGCCATTACCCGAATCGTTGGACTACTGGTCATCTTATTTTCAGGGACCATGATTATCCCTGGGCTGGT
AGCACTCATCTACCGGGATGGAGCGGGACGCGCTTTTACCCAGACCTTTTTTGTCGCCCTCGCCATTGGCTCTATGCTTT
GGTGGCCGAACCGCAAAGAGAAGGGCGAACTGAAATCCCGTGAGGGGTTTCTGATAGTGGTGCTGTTCTGGACCGTGCTG
GGTAGCGTCGGTGCGCTCCCTTTTATCTTCTCGGAAAGCCCGAACCTCACGATTACCGATGCGTTTTTTGAATCTTTCTC
TGGCCTGACCACCACGGGGGCCACTACGCTGGTGGGGCTGGATTCGCTCCCTCATGCCATCCTCTTTTATCGCCAGATGC
TGCAATGGTTTGGCGGTATGGGGATCATCGTGCTGGCGGTTGCGATACTGCCTATCCTCGGCGTGGGTGGGATGCAGCTC
TATCGCGCAGAAATGCCCGGCCCGCTGAAAGATAACAAAATGCGCCCGCGAATTGCGGAAACGGCGAAAACCCTGTGGTT
GATTTATGTCTTGCTGACCGTCGCCTGTGCGCTGGCGTTGTGGTTTGCTGGAATGGATGCCTTTGATGCCATCGGCCATA
GCTTTGCGACCATCGCTATTGGCGGCTTCTCGACACATGATGCCAGTATCGGTTATTTCGACAGCCCGACTATTAACACT
ATCATTGCTATCTTCCTGCTGATCTCTGGCTGTAACTACGGTCTGCACTTTTCACTGTTAAGTGGGCGTAGTCTGAAGGT
TTATTGGCGCGATCCGGAATTTCGCATGTTTATCGGCGTACAGTTTTCACTGGTGGTTATTTGTACACTCGTACTGTGGT
TTCATAATGTCTACAGTTCGGCGCTGATGACAATTAACCAGGCGTTTTTCCAGGTGGTGTCGATGGCGACAACCGCCGGG
TTTACAACTGACAGCATTGCCCGCTGGCCGCTCTTTTTGCCGGTACTGCTTTTATGTTCAGCTTTTATCGGCGGTTGCGC
CGGGTCAACGGGCGGTGGCCTGAAAGTGATCCGCATCCTGCTGCTGTTTAAGCAGGGGAACCGTGAGCTGAAACGACTGG
TGCATCCGAACGCCGTCTATAGCATTAAGCTGGGGAATCGCGCACTGCCGGAACGTATCCTCGAAGCCGTTTGGGGATTT
TTCTCCGCCTATGCATTGGTGTTTATTGTCAGTATGCTGGCGATTATCGCCACGGGCGTGGATGACTTTTCTGCCTTTGC
CTCGGTTGTTGCAACATTGAATAACCTGGGGCCAGGGCTTGGCGTGGTTGCTGATAACTTTACCAGTATGAACCCGGTGG
CTAAATGGATCCTGATTGCCAACATGCTGTTTGGTCGTCTCGAGGTCTTTACATTGCTGGTGCTCTTTACCCCGACTTTC
TGGCGTGAATGA

Upstream 100 bases:

>100_bases
TTTCCGCAAAGCTGGCGGATTTTAGCCGTGGTTCATTGCAATTGTTAGCGATTGAAGAATAATCCCCACTTCGTTTTGCA
GAACTAAGGAAGCGGCAGAG

Downstream 100 bases:

>100_bases
TGGAGTAATACGTGAAAACATTAATTCTTTTCTCAACAAGGGACGGACAAACGCGCGAGATTGCCTCCTACCTGGCTTCG
GAACTGAAAGAACTGGGGAT

Product: potassium transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVL
GSVGALPFIFSESPNLTITDAFFESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATIAIGGFSTHDASIGYFDSPTINT
IIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQFSLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAG
FTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGF
FSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSMNPVAKWILIANMLFGRLEVFTLLVLFTPTF
WRE

Sequences:

>Translated_483_residues
MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVL
GSVGALPFIFSESPNLTITDAFFESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATIAIGGFSTHDASIGYFDSPTINT
IIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQFSLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAG
FTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGF
FSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSMNPVAKWILIANMLFGRLEVFTLLVLFTPTF
WRE
>Mature_483_residues
MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVL
GSVGALPFIFSESPNLTITDAFFESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATIAIGGFSTHDASIGYFDSPTINT
IIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQFSLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAG
FTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGF
FSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSMNPVAKWILIANMLFGRLEVFTLLVLFTPTF
WRE

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=483, Percent_Identity=99.7929606625259, Blast_Score=965, Evalue=0.0,
Organism=Escherichia coli, GI1787626, Length=482, Percent_Identity=40.8713692946058, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52946; Mature: 52946

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKE
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
KGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAFFESFSGLTTTGATTLVGL
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCEEEEHHHHHHCCCCCCCCCHHHHCC
DSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQLYRAEMPGPLKDNKMRPRIAE
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATIAIGGFSTHDASIGYFDSPTINT
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHH
IIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQFSLVVICTLVLWFHNVYSS
HHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
ALMTINQAFFQVVSMATTAGFTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRIL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGFFSAYALVFIVSMLAIIATGV
HHHHCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DDFSAFASVVATLNNLGPGLGVVADNFTSMNPVAKWILIANMLFGRLEVFTLLVLFTPTF
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
WRE
CCC
>Mature Secondary Structure
MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKE
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
KGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAFFESFSGLTTTGATTLVGL
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCEEEEHHHHHHCCCCCCCCCHHHHCC
DSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQLYRAEMPGPLKDNKMRPRIAE
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATIAIGGFSTHDASIGYFDSPTINT
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHH
IIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQFSLVVICTLVLWFHNVYSS
HHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
ALMTINQAFFQVVSMATTAGFTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRIL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGFFSAYALVFIVSMLAIIATGV
HHHHCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DDFSAFASVVATLNNLGPGLGVVADNFTSMNPVAKWILIANMLFGRLEVFTLLVLFTPTF
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
WRE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]