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The map label for this gene is aslB [H]

Identifier: 218692076

GI number: 218692076

Start: 4418886

End: 4420121

Strand: Direct

Name: aslB [H]

Synonym: ECED1_4483

Alternate gene names: 218692076

Gene position: 4418886-4420121 (Clockwise)

Preceding gene: 218692075

Following gene: 218692082

Centisome position: 84.82

GC content: 50.97

Gene sequence:

>1236_bases
ATGCAGCAACAGGTTCCAACGCGTGCTTTTCATGTGATGGCGAAACCGAGCGGTTCTGATTGTAATCTGAACTGTGACTA
CTGTTTTTATCTCGAAAAACAATCCCTTTACCACGAAAAGCCAGTCACGCATATGGACGATGACACGCTGGAAGCGTATG
TCCGTCACTATATCGCTGCCAGCGAAACCCAAAACGAAGTGGCTTTTACCTGGCAGGGCGGCGAACCAACGTTACTCGGG
CTGGATTTTTACCGCCGTGCCGTGGCGCTACAGGCGAAATATGGTGCTGGCAGGAAGATAAGTAATAGCTTCCAGACTAA
CGGCGTGCTGCTCGATGACGAATGGTGTGCATTTCTGGCAGAAAATCATTTTCTTGTAGGGTTATCGCTGGATGGTCCGG
CTGAGATCCACAATCAATATCGCGTGACCAAAGGTGGCAGACCAACGCATAAGCTGGTGATGCGTGCTCTGACGCTCCTG
CAAAAACATCATGTCGACTATAACGTGCTGGTCTGCGTCAATCGCACCAGTGCGTTACAACCTTTGCAAGTCTATGATTT
TCTGTGTGATGCAGGTGTTGAGTTCATCCAGTTTATTCCGGTGGTCGAGCGCCTGGCTGATGAAACGGCTGCTCATGCTG
GACTTAAGCTACATGCTCCCGGCGATATTCAGGGCGAACTGACGGAATGGTCGGTGTGCCCGCAAGAGTTCGGTGAGTTT
CTGGTGGCGATTTTCGACCACTGGATTAAGCGCGACGTCGGCAAGATTTTCGTAATGAATATCGAATGGGCGTTCGCCAA
TTTTGTCGGCGCACCGGGCGCGGTTTGCCATCATCAGCCAACCTGTGGGCGCTCGGTGATTGTTGAGCACAACGGTGACG
TTTATGCCTACGATCACTATGTTTATCCGCAGTATCGACTAGGGAATATGCTTCAGCAGATGATTGCAGAAATGATTGAT
TCCCCGCAACAGCAGGCATTTGGTGAAGATAAATTCAAGCAGTTACCGGCACAGTGTCGCAGTTGCAACGTGTTAAAAGC
GTGCTGGGGAGGCTGCCCGAAACACCGCTTTATGCTCGATGCCAGCGGCAAACCCGGGCTGAATTATTTGTGTGCCGGGT
ATCAGCGTTATTTCCGCCATCTACCGCCATATCTTAAAGCAATGGTTGATTTGCTGGCGCACGGTCGTCCGGCCAGCGAC
ATTATGCAGGCGCATTTGCTGGTGGTGAATAAGTAA

Upstream 100 bases:

>100_bases
GTCACTTTCCCTTCGCAATAAACGCCCGTAATAACGCATTGCGCCACGGTATGATTTCGCCCTTAACTTATTGAAGGATG
ACTTCAGGCAAGGAGCGACC

Downstream 100 bases:

>100_bases
AAAAGCAGCCATTTTGTGGCCGCCTGCGGTTGATTGTCGGATGCGTCAGCATCGCATCCGGCAAAGGTAGATCTCAGCGA
TAGCGCCGGCTTAATCAGAT

Product: regulator of arylsulfatase activity

Products: NA

Alternate protein names: AnSME homolog [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MQQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYHEKPVTHMDDDTLEAYVRHYIAASETQNEVAFTWQGGEPTLLG
LDFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSALQPLQVYDFLCDAGVEFIQFIPVVERLADETAAHAGLKLHAPGDIQGELTEWSVCPQEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYAYDHYVYPQYRLGNMLQQMIAEMID
SPQQQAFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMVDLLAHGRPASD
IMQAHLLVVNK

Sequences:

>Translated_411_residues
MQQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYHEKPVTHMDDDTLEAYVRHYIAASETQNEVAFTWQGGEPTLLG
LDFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSALQPLQVYDFLCDAGVEFIQFIPVVERLADETAAHAGLKLHAPGDIQGELTEWSVCPQEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYAYDHYVYPQYRLGNMLQQMIAEMID
SPQQQAFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMVDLLAHGRPASD
IMQAHLLVVNK
>Mature_411_residues
MQQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYHEKPVTHMDDDTLEAYVRHYIAASETQNEVAFTWQGGEPTLLG
LDFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSALQPLQVYDFLCDAGVEFIQFIPVVERLADETAAHAGLKLHAPGDIQGELTEWSVCPQEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYAYDHYVYPQYRLGNMLQQMIAEMID
SPQQQAFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMVDLLAHGRPASD
IMQAHLLVVNK

Specific function: Potential Positive Factor For The Regulation Of Arylsulfatase. [C]

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=411, Percent_Identity=95.6204379562044, Blast_Score=819, Evalue=0.0,
Organism=Escherichia coli, GI87081923, Length=393, Percent_Identity=41.7302798982188, Blast_Score=328, Evalue=5e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 46459; Mature: 46459

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00028 ZINC_FINGER_C2H2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYHEKPVTHMDDDTLEAYVRHYIAA
CCCCCCCHHEEEEECCCCCCCCCCCCEEEEECHHHHHHCCCCCCCCCHHHHHHHHHHHHH
SETQNEVAFTWQGGEPTLLGLDFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLA
CCCCCCEEEEEECCCCEEECHHHHHHHHHEEECCCCCCCCCCCCCCCCEEECCHHHHHHH
ENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLLQKHHVDYNVLVCVNRTSALQ
CCEEEEEEECCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
PLQVYDFLCDAGVEFIQFIPVVERLADETAAHAGLKLHAPGDIQGELTEWSVCPQEFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHCCCHHHHHHH
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYAYDHY
HHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEE
VYPQYRLGNMLQQMIAEMIDSPQQQAFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLD
ECCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEE
ASGKPGLNYLCAGYQRYFRHLPPYLKAMVDLLAHGRPASDIMQAHLLVVNK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHEEEECC
>Mature Secondary Structure
MQQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYHEKPVTHMDDDTLEAYVRHYIAA
CCCCCCCHHEEEEECCCCCCCCCCCCEEEEECHHHHHHCCCCCCCCCHHHHHHHHHHHHH
SETQNEVAFTWQGGEPTLLGLDFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLA
CCCCCCEEEEEECCCCEEECHHHHHHHHHEEECCCCCCCCCCCCCCCCEEECCHHHHHHH
ENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLLQKHHVDYNVLVCVNRTSALQ
CCEEEEEEECCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
PLQVYDFLCDAGVEFIQFIPVVERLADETAAHAGLKLHAPGDIQGELTEWSVCPQEFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHCCCHHHHHHH
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYAYDHY
HHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEE
VYPQYRLGNMLQQMIAEMIDSPQQQAFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLD
ECCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEE
ASGKPGLNYLCAGYQRYFRHLPPYLKAMVDLLAHGRPASDIMQAHLLVVNK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503; 11222759 [H]