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The map label for this gene is yifK [H]

Identifier: 218692075

GI number: 218692075

Start: 4416815

End: 4418200

Strand: Direct

Name: yifK [H]

Synonym: ECED1_4481

Alternate gene names: 218692075

Gene position: 4416815-4418200 (Clockwise)

Preceding gene: 218692074

Following gene: 218692076

Centisome position: 84.78

GC content: 52.67

Gene sequence:

>1386_bases
ATGGCAGATAACAAACCAGAGCTACAGCGTGGGCTGGAAGCTCGACATATCGAACTCATCGCCCTGGGGGGCACCATTGG
CGTCGGCCTGTTTATGGGGGCCGCCAGTACCCTGAAATGGGCCGGGCCATCCGTATTGTTGGCCTATATCATCGCCGGGC
TGTTCGTCTTTTTCATCATGCGTTCAATGGGCGAAATGTTGTTCCTCGAACCGGTTACCGGTTCGTTCGCCGTTTACGCG
CATCGTTATATGAGCCCGTTCTTTGGTTATCTCACCGCCTGGTCTTACTGGTTTATGTGGATGGCGGTGGGGATCTCAGA
AATCACCGCCATTGGCGTTTATGTCCAGTTCTGGTTCCCGGAGATGGCGCAGTGGATACCCGCATTGATCGCGGTGGCGC
TGGTGGCGTTGGCGAATCTGGCTGCGGTGAGGTTGTACGGCGAAATAGAGTTCTGGTTCGCGATGATCAAAGTCACCACG
ATTATCGTGATGATTGTCATTGGCCTGGGCGTGATTTTCTTTGGCTTTGGCAATGGCGGGCAGTCGATTGGTTTTAGCAA
TCTCACAGAGCATGGCGGTTTCTTTGCTGGTGGCTGGAAAGGGTTCCTGACCGCATTGTGTATTGTGGTGGCGTCCTACC
AGGGCGTGGAGCTGATTGGCATTACTGCCGGTGAAGCGAAGAATCCGCAGGTGACGCTGCGCAGTGCCGTAGGCAAGGTG
CTGTGGCGAATCCTGATTTTCTACGTTGGCGCGATTTTCGTTATCGTTACTATCTTCCCGTGGAATGAAATAGGCAGCAA
CGGTAGCCCGTTCGTACTGACTTTCGCCAAAATCGGCATTACCGCAGCGGCGGGCATTATCAACTTTGTGGTGCTGACGG
CTGCGCTCTCTGGCTGTAACAGCGGCATGTACAGTTGCGGACGTATGCTCTATGCACTGGCGAAAAACCGTCAGTTACCG
GCGGCAATGGCGAAAGTTTCCCGTCACGGCGTACCGGTTGCGGGTGTGGCAGTATCTATTGCTATTCTGCTAATTGGCTC
ATGCCTGAACTACATCATTCCCAATCCGCAGCGTGTGTTTGTTTACGTCTACAGTGCCAGCGTGCTTCCGGGGATGGTGC
CATGGTTTGTGATATTGATAAGCCAGCTGCGTTTTCGTCGTGCGCATAAAGCAGCAATTGCCAGCCATCCGTTCCGCTCA
ATCCTGTTCCCTTGGGCCAACTACGTAACAATGGCATTCCTGATTTGCGTTTTGATCGGCATGTACTTTAATGAAGATAC
GCGTATGTCGCTGTTTGTCGGCATCATCTTTATGCTGACGGTGACGGCGATTTATAAAGTTTTTGGGCTTAATCGCCACG
GTAAAGCGCATAAACTGGAGGAATAA

Upstream 100 bases:

>100_bases
TTGCCATTTCTCCTGAATTACGAAAACATTCGCAACACTCGATGTACCCATAACGATAACCGGTAACACCGGAAAGCATG
CAAACACAACACGAGGATTT

Downstream 100 bases:

>100_bases
GCAGCAAAACGCACAAACCGTAACCAAACGCGCAATTTATTTAAAAAGGGACTAGACAGAGGGGTGGGAAGTCCGTATTA
TCCACCCCCGCAACGGCGCT

Product: putative transport protein YifK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA
HRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP
AAMAKVSRHGVPVAGVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRS
ILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLTVTAIYKVFGLNRHGKAHKLEE

Sequences:

>Translated_461_residues
MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA
HRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP
AAMAKVSRHGVPVAGVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRS
ILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLTVTAIYKVFGLNRHGKAHKLEE
>Mature_460_residues
ADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAH
RYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTI
IVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKVL
WRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPA
AMAKVSRHGVPVAGVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRSI
LFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLTVTAIYKVFGLNRHGKAHKLEE

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI48994972, Length=461, Percent_Identity=99.7830802603037, Blast_Score=917, Evalue=0.0,
Organism=Escherichia coli, GI1786789, Length=429, Percent_Identity=44.0559440559441, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1786302, Length=431, Percent_Identity=40.1392111368909, Blast_Score=343, Evalue=2e-95,
Organism=Escherichia coli, GI1786602, Length=460, Percent_Identity=44.7826086956522, Blast_Score=337, Evalue=7e-94,
Organism=Escherichia coli, GI1790653, Length=464, Percent_Identity=38.3620689655172, Blast_Score=334, Evalue=6e-93,
Organism=Escherichia coli, GI87081915, Length=392, Percent_Identity=39.2857142857143, Blast_Score=294, Evalue=8e-81,
Organism=Escherichia coli, GI1788480, Length=435, Percent_Identity=39.0804597701149, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI87081708, Length=471, Percent_Identity=36.7303609341826, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1789017, Length=464, Percent_Identity=32.9741379310345, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI2367353, Length=460, Percent_Identity=25.2173913043478, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6324061, Length=438, Percent_Identity=35.1598173515982, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6320772, Length=439, Percent_Identity=34.3963553530752, Blast_Score=220, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6324924, Length=414, Percent_Identity=32.3671497584541, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324990, Length=447, Percent_Identity=30.4250559284116, Blast_Score=193, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6322892, Length=437, Percent_Identity=30.8924485125858, Blast_Score=190, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6324059, Length=439, Percent_Identity=33.0296127562642, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322967, Length=415, Percent_Identity=30.3614457831325, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6321629, Length=404, Percent_Identity=27.970297029703, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6319824, Length=436, Percent_Identity=28.4403669724771, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6321053, Length=421, Percent_Identity=29.2161520190024, Blast_Score=167, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6319608, Length=422, Percent_Identity=28.9099526066351, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324981, Length=410, Percent_Identity=30.4878048780488, Blast_Score=160, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6319543, Length=400, Percent_Identity=29.25, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6324553, Length=397, Percent_Identity=30.9823677581864, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6319542, Length=403, Percent_Identity=27.2952853598015, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6320717, Length=439, Percent_Identity=24.6013667425968, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6320251, Length=400, Percent_Identity=26.5, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6320364, Length=555, Percent_Identity=23.7837837837838, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221512776, Length=360, Percent_Identity=21.9444444444444, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24666159, Length=360, Percent_Identity=21.9444444444444, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50430; Mature: 50299

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIM
CCCCCHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFP
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTIIVMIVIGLGVIFFGFGNGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
QSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
CCCCCCCHHHCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCN
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
SGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVAGVAVSIAILLIGSCLNYIIPNPQRVF
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRSILFPWANYVTMAFLICVLIG
EEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MYFNEDTRMSLFVGIIFMLTVTAIYKVFGLNRHGKAHKLEE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIM
CCCCHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFP
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTIIVMIVIGLGVIFFGFGNGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
QSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
CCCCCCCHHHCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCN
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
SGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVAGVAVSIAILLIGSCLNYIIPNPQRVF
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRSILFPWANYVTMAFLICVLIG
EEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MYFNEDTRMSLFVGIIFMLTVTAIYKVFGLNRHGKAHKLEE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]