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The map label for this gene is hdfR [H]

Identifier: 218692044

GI number: 218692044

Start: 4383930

End: 4384769

Strand: Reverse

Name: hdfR [H]

Synonym: ECED1_4451

Alternate gene names: 218692044

Gene position: 4384769-4383930 (Counterclockwise)

Preceding gene: 218692046

Following gene: 218692043

Centisome position: 84.17

GC content: 48.1

Gene sequence:

>840_bases
GTGGATACGGAATTGTTAAAAACTTTCCTGGAAGTTAGCCGAACGCGTCACTTTGGTCGAGCGGCTGAATCGCTCTATCT
GACCCAATCAGCCGTGAGCTTTCGAATCAGACAACTGGAAAATCAACTGGGTGTGAATCTTTTCACCCGCCACAGAAACA
ATATCCGTTTAACCGCTGCCGGAGAAAAGCTTCTGCCTTATGCAGAAACGCTCATGAGCACCTGGCAGGCCGCCCGCAAG
GAGGTGGCGCATACCTCACGACATAATGAGTTTTCTATCGGTGCCAGCGCCTCGCTGTGGGAGTGTATGCTTAATCAGTG
GCTGGGACGCTTGTATCAAAATCAGGATGTCCATACAGGCTTACAGTTCGAAGCGCGAATTGCCCAACGGCAGTCTCTGG
TAAAACAGTTGCATGAACGCCAGCTTGATCTTCTTATTACAACTGAAGCCCCCAAAATGGACGAATTTTGTAGTCAGTTG
CTGGGGTATTTCACTTTAGCGCTTTATACCAGTGCCCCTTCTAAACTAAAGGGAGATCTTAACTATCTGCGACTAGAGTG
GGGGCCAGATTTTCAACAGCATGAGGCAGGTTTGATCGGTGCTGACGAAGTTCCCATTCTGACAACCAGTTCTGCTGAAC
TGGCACAGCAACAGATTGCGATGCTTAATGGTTGCACCTGGCTACCCGTCAGTTGGGCACGTAAAAAAGGCGGCCTGCAT
ACCGTTGTCGATAGCACAACACTTTCACGGCCGCTTTATGCCATATGGCTACAAAATAGCGATAAAAATGCGTTGATTCG
CGATCTATTGAAAATTAACGTGCTGGATGAAGTGTATTAA

Upstream 100 bases:

>100_bases
TTTGACCGAGCTAGTTATGGCGCGGAGTATTAGTTACGCTTGACAGAGTGTAAAACAAAACATTTAAATCATAACGACAA
ATAATTTTGCGGAGAGCACT

Downstream 100 bases:

>100_bases
TCTGAATGGCTGGCAAGGATGCCGGTAGAAGGAGTTACTTCGGAGAGGGTTATTTCAGATAAAAAAAATCCTTAGCTTTC
GCTAAGGATGATTTCTGGCA

Product: transcriptional regulator HdfR

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARK
EVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDVHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFCSQL
LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLH
TVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY

Sequences:

>Translated_279_residues
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARK
EVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDVHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFCSQL
LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLH
TVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
>Mature_279_residues
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARK
EVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDVHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFCSQL
LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLH
TVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=279, Percent_Identity=99.2831541218638, Blast_Score=572, Evalue=1e-164,
Organism=Escherichia coli, GI1788626, Length=151, Percent_Identity=31.1258278145695, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367136, Length=252, Percent_Identity=26.1904761904762, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790399, Length=265, Percent_Identity=26.4150943396226, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790208, Length=68, Percent_Identity=44.1176470588235, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787601, Length=157, Percent_Identity=27.3885350318471, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31791; Mature: 31791

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEC
GEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDVHTG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
LQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFCSQLLGYFTLALYTSAPSKLKGDL
CHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCC
NYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLH
EEEEEECCCCHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCHHHHHCCCEE
TVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
EEECCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEC
GEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDVHTG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
LQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFCSQLLGYFTLALYTSAPSKLKGDL
CHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCC
NYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLH
EEEEEECCCCHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCHHHHHCCCEE
TVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
EEECCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA