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The map label for this gene is ftsY [H]

Identifier: 218691749

GI number: 218691749

Start: 4044870

End: 4046366

Strand: Reverse

Name: ftsY [H]

Synonym: ECED1_4137

Alternate gene names: 218691749

Gene position: 4046366-4044870 (Counterclockwise)

Preceding gene: 218691752

Following gene: 218691748

Centisome position: 77.67

GC content: 53.31

Gene sequence:

>1497_bases
ATGGCGAAAGAAAAAAAACGTGGCTTTTTTTCCTGGCTGGGCTTTGGTCAAAAAGAGCAGACCCCGGAAAAAGAGACAGA
AGTTCAGAATGAACAACCAGTTGTAGAAGAAATCGTTCAGGCGCAAGAGCCTGTGAAGGCTTCTGAACACGCCGTTGAAG
AGCAGCCGCAGGCGCATACTGAAGCCGAGGCGGAAACTTTTGCTGCCGACGTTGTGGAAGTTACTGAACAGGTTGCTGAA
AGTGAAAAAGCGCAGCCTGAAGCGGAAGTCGTTGCACAGCCGGAACCGGTCGTAGAAGAAACGCCGGAGCCAGTGGCTAT
CGAACGTGAAGAACTGCCGTTGCCGGAAGACGTCAACGCCGAAGCGGTTTCGCCAGAAGAGTGGCAGGCCGAAGCGGAAA
CCGTAGAGATTGTCGAAGCGGCGGAAGAAGAAGCGGCTAAAGAAGAAATCACCGACGAAGAGCCGGAGGCACAGGCGCTG
GCTGCCGAAGCGGCAGAAGAGGCGGTAATGGTGGTTTCTCCGGCAGAAGAAGAGCAGCCGGTGGAAGAAATCGCTCAGGA
GCAGGAAAAACCGACCAAAGAAGGTTTCTTCGCGCGCCTGAAACGCAGCCTGTTAAAAACCAAAGAAAATCTCGGTTCCG
GATTTATCAGCCTGTTCCGCGGTAAAAAAATCGACGATGATCTGTTTGAAGAGCTGGAAGAACAGCTGTTGATCGCCGAT
GTGGGCGTGGAAACCACACGTAAAATTATCACCAATCTGACAGAAGGCGCATCCCGCAAGCAGCTTCGTGATGCCGAGGC
GCTCTATGGCCTGCTGAAAGAAGAGATGGGCGAGATTCTGGCGAAAGTCGATGAGCCGCTGAATGTTGAAGGTAAAACGC
CGTTCGTGATCCTGATGGTGGGCGTCAACGGTGTGGGTAAAACCACGACGATTGGTAAGCTGGCGCGTCAGTTTGAGCAG
CAGGGTAAATCGGTGATGCTGGCGGCAGGCGATACTTTCCGTGCGGCAGCGGTTGAACAGCTTCAGGTCTGGGGTCAGCG
CAACAATATTCCGGTGATTGCCCAGCATACCGGTGCTGATTCCGCTTCTGTTATCTTCGACGCCATTCAGGCCGCTAAAG
CGCGTAACATCGACGTCCTGATTGCCGATACCGCCGGACGCCTGCAAAACAAATCGCACCTGATGGAAGAGTTGAAGAAA
ATCGTCCGCGTGATGAAGAAACTCGACGTTGAAGCTCCGCATGAAGTTATGCTGACTATTGATGCCAGCACCGGGCAGAA
TGCGGTAAGCCAGGCCAAACTGTTCCACGAAGCCGTTGGCTTAACCGGCATCACGCTAACGAAACTGGACGGCACGGCGA
AAGGCGGGGTAATTTTCTCGGTGGCTGACCAGTTTGGTATCCCTATCCGCTACATTGGTGTCGGCGAACGTATTGAGGAT
TTGCGTCCGTTTAAGGCGGACGACTTTATAGAGGCACTTTTTGCCCGAGAGGATTAA

Upstream 100 bases:

>100_bases
GAATTAAGTTAAGTGATAGACTATTTCATCATTTTTTTAGCTGCTATGTACATAGCGTTAACGCTGTGCCATGAAGCAAC
AGCGAGGAGTGTAGTCGCAA

Downstream 100 bases:

>100_bases
CAATGATTCGCTTTGAACATGTCAGCAAGGCTTATCTCGGTGGGAGACAGGCGCTGCAGGGCGTTACGTTCCATATGCAG
CCGGGTGAGATGGCGTTTCT

Product: cell division protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEHAVEEQPQAHTEAEAETFAADVVEVTEQVAE
SEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEEPEAQAL
AAEAAEEAVMVVSPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIAD
VGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTIGKLARQFEQ
QGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKK
IVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIED
LRPFKADDFIEALFARED

Sequences:

>Translated_498_residues
MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEHAVEEQPQAHTEAEAETFAADVVEVTEQVAE
SEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEEPEAQAL
AAEAAEEAVMVVSPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIAD
VGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTIGKLARQFEQ
QGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKK
IVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIED
LRPFKADDFIEALFARED
>Mature_497_residues
AKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEHAVEEQPQAHTEAEAETFAADVVEVTEQVAES
EKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEEPEAQALA
AEAAEEAVMVVSPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIADV
GVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQ
GKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKI
VRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDL
RPFKADDFIEALFARED

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=276, Percent_Identity=31.1594202898551, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI226371618, Length=203, Percent_Identity=35.9605911330049, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI23308697, Length=225, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI295424842, Length=225, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI89061728, Length=147, Percent_Identity=32.6530612244898, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1789874, Length=498, Percent_Identity=98.5943775100402, Blast_Score=882, Evalue=0.0,
Organism=Escherichia coli, GI1788963, Length=311, Percent_Identity=32.7974276527331, Blast_Score=159, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI193206261, Length=319, Percent_Identity=31.0344827586207, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17539958, Length=281, Percent_Identity=27.4021352313167, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=288, Percent_Identity=32.6388888888889, Blast_Score=136, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6320498, Length=223, Percent_Identity=34.0807174887892, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17647949, Length=283, Percent_Identity=31.095406360424, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24641198, Length=333, Percent_Identity=27.6276276276276, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 54625; Mature: 54494

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEHAVEEQPQAHT
CCCCHHCCHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCHHH
EAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHCCCCCCEECHHCCCCCCCCCC
EAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEEPEAQALAAEAAEEAVMVVSPAEEEQP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCEEEEECCCCCCCH
VEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIAD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKTPFVILMV
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGAD
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCC
SASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTI
HHHHHHHHHHHHHCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIED
ECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEHHHHCCCEEEECCCHHHHH
LRPFKADDFIEALFARED
CCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEHAVEEQPQAHT
CCCHHCCHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCHHH
EAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHCCCCCCEECHHCCCCCCCCCC
EAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEEPEAQALAAEAAEEAVMVVSPAEEEQP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCEEEEECCCCCCCH
VEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIAD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKTPFVILMV
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGAD
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCC
SASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTI
HHHHHHHHHHHHHCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIED
ECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEHHHHCCCEEEECCCHHHHH
LRPFKADDFIEALFARED
CCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]