Click here to switch to the map view.

The map label for this gene is yeeJ [C]

Identifier: 218690629

GI number: 218690629

Start: 2896033

End: 2897982

Strand: Reverse

Name: yeeJ [C]

Synonym: ECED1_2940

Alternate gene names: 218690629

Gene position: 2897982-2896033 (Counterclockwise)

Preceding gene: 218690630

Following gene: 218690628

Centisome position: 55.63

GC content: 48.87

Gene sequence:

>1950_bases
TTGACCCCTGAGGCGCTGGAATCTCAGGCCAGAAGCTATCTGCAAAGTCAAATCACCTCAACCGCACAATCTTATATTGA
AGACACACTCTCTCCCTACGGTAAGGTCCGTTCGAACCTCTCCATTGGTCAGGGCGGCGATCTGGATGGCAGTTCCATCG
ATTATTTTGTTCCCTGGTACGATAATCAAACCACTGTTTATTTCAGCCAATTTTCTGCGCAACGAAAAGAAGATCGTACG
ATCGGGAATATTGGCCTTGGGGTAAGGTATAATTTTGATAAATATCTATTGGGTGGAAATATATTTTATGATTATGACTT
TACCCGTGGACATCGCCGTTTAGGTTTAGGCGCCGAAGCCTGGACGGATTATTTAAAATTCTCAGGCAACTATTATCACC
CACTTTCTGACTGGAAAGACTCTGAAGATTTCGACTTTTATGAAGAACGCCCTGCGCGCGGCTGGGATATTCGCGCTGAA
GCCTGGCTACCCGCTTACCCGCAGCTTGGCGGAAAAATTGTCTTCGAACAATATTATGGGAATGAAGTCGCGCTTTTTGG
TACCGATAGTCTGGAGAAAGATCCCTTCGCTGTCACGCTGGGTGTGAAATACCAGCCCGTTCCGCTCATTGTTGTCGGTA
CAGATTTCAAAGCTGGCACTGGCGATAATACCGATCTTTCTGTTAACGCAACGCTGAACTACCAGTTTGGCGTCCCGCTC
AAAGACCAGCTTGATCCTGACAAAGTGAGCGCGGCTCACTCGCTCATGGGTAGCCGTCATGACTTTGTTGAACGTAACAA
CTTTATTGTTCTGGAATACAAAGAGAAAGATCCCCTCTATGTCACTTTGTGGCTGAAAGCCGACGTCACGAATGAACATC
CCGAGTGCGTGATTAAAGATACGCCCGAAGAAGCCGTCGGTCTGGAAAAATGTAAGTGGACCATTAACGCACTCATTAAT
CATCATTACAAAATCGTTGCTGCCTCCTGGCAGGTGAAAAACAATGCTGCCCGCACGCTGGTGATGCCGGTTATCAAAGA
GAATACTCTGACAGAGGGTAACAATAACCACTGGAACCTGGTGCTGCCTGCCTGGCAGTACAGTTCCGATCAAGCCGAAC
AAGAAAAACTCAACACCTGGCGGGTACGCCTGGCGCTGGAAGATGAAAAAGGCAATCGGCAGAGCTCCGGTGTGGTGGAA
ATCACCGTTCAACAGGACCGTAAAATTGAGCTCATCGTTAACAACATCGCCAATGTCCCGGATAAGAGCAATCACAGCCA
CGAAGCCAGCGCACAGGCCGATGGTGTAGATGGTGTAGTGATGGATCTCGATGTAACCGACCGCAATGGCGATGCGCTGC
CGGAAGATAACCTCACGCCGCAGCTTTACGACGCGCAGGACAAACGAGTGACGTTAACCAACAAGCCTTGCTCGACCGAC
AACCCCTGCGTTTTTATCGCTAAACAAGATAAAGAAAAGGGCACTGTCACCCTCTCCAGTACCTTACCCGGCACCTATCG
CTGGAAAGCAAAAGCCGCGCCCTACGATGACAGTAACTATGTGGATGTCACTTTCCTCGGGGCAGAAATTGGTGGGCTAA
ATGCTTTTATCTATCGAGTGGGGGCGGCTAAACCCAGCAACCTGATAGGTAAAGATAAAGAACCGTTGCCGCTTAACAAC
ATTTATCGATTTGTTTTATGGCGCGACAACAATAAAGACGGTGTCTTCCAGCAGGTCGAAAAACTGACTGACGAAGAGAT
GGCGCAGTACGACTACAAGTGGGAATTTACCGGCAAGAGCATCAATGGTGAAGTGGATGCACAGGCGAACACTTCCAATG
AGGACATTGTGATTCCGGCCACTAACCGTGAAGCGGCGCAAACCTATGGCGCACAAGCGGGAGATGGCTTGCAGGGGTAC
GGTTTACGCGTGCTGTATACCAAAAAATAA

Upstream 100 bases:

>100_bases
CTAGGCAGCACAACAGGATGAACAAACCAACAAGGGTAAATCGCTGAAAGAGCGCGGAGCCGATTACGTCATCAACTCCG
CCACGCAAGGGTTTGAAAAC

Downstream 100 bases:

>100_bases
GATTGGCGTAAGGCCAGTCGGCCAGTCGCTGAAGGTTCATTAAGGAGAGCATCAATGAAGCAGGATAAAAGACGCGGTCT
GACCCGGATCGCATTAGCGC

Product: putative intimin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 649; Mature: 648

Protein sequence:

>649_residues
MTPEALESQARSYLQSQITSTAQSYIEDTLSPYGKVRSNLSIGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRT
IGNIGLGVRYNFDKYLLGGNIFYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAE
AWLPAYPQLGGKIVFEQYYGNEVALFGTDSLEKDPFAVTLGVKYQPVPLIVVGTDFKAGTGDNTDLSVNATLNYQFGVPL
KDQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLYVTLWLKADVTNEHPECVIKDTPEEAVGLEKCKWTINALIN
HHYKIVAASWQVKNNAARTLVMPVIKENTLTEGNNNHWNLVLPAWQYSSDQAEQEKLNTWRVRLALEDEKGNRQSSGVVE
ITVQQDRKIELIVNNIANVPDKSNHSHEASAQADGVDGVVMDLDVTDRNGDALPEDNLTPQLYDAQDKRVTLTNKPCSTD
NPCVFIAKQDKEKGTVTLSSTLPGTYRWKAKAAPYDDSNYVDVTFLGAEIGGLNAFIYRVGAAKPSNLIGKDKEPLPLNN
IYRFVLWRDNNKDGVFQQVEKLTDEEMAQYDYKWEFTGKSINGEVDAQANTSNEDIVIPATNREAAQTYGAQAGDGLQGY
GLRVLYTKK

Sequences:

>Translated_649_residues
MTPEALESQARSYLQSQITSTAQSYIEDTLSPYGKVRSNLSIGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRT
IGNIGLGVRYNFDKYLLGGNIFYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAE
AWLPAYPQLGGKIVFEQYYGNEVALFGTDSLEKDPFAVTLGVKYQPVPLIVVGTDFKAGTGDNTDLSVNATLNYQFGVPL
KDQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLYVTLWLKADVTNEHPECVIKDTPEEAVGLEKCKWTINALIN
HHYKIVAASWQVKNNAARTLVMPVIKENTLTEGNNNHWNLVLPAWQYSSDQAEQEKLNTWRVRLALEDEKGNRQSSGVVE
ITVQQDRKIELIVNNIANVPDKSNHSHEASAQADGVDGVVMDLDVTDRNGDALPEDNLTPQLYDAQDKRVTLTNKPCSTD
NPCVFIAKQDKEKGTVTLSSTLPGTYRWKAKAAPYDDSNYVDVTFLGAEIGGLNAFIYRVGAAKPSNLIGKDKEPLPLNN
IYRFVLWRDNNKDGVFQQVEKLTDEEMAQYDYKWEFTGKSINGEVDAQANTSNEDIVIPATNREAAQTYGAQAGDGLQGY
GLRVLYTKK
>Mature_648_residues
TPEALESQARSYLQSQITSTAQSYIEDTLSPYGKVRSNLSIGQGGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTI
GNIGLGVRYNFDKYLLGGNIFYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEA
WLPAYPQLGGKIVFEQYYGNEVALFGTDSLEKDPFAVTLGVKYQPVPLIVVGTDFKAGTGDNTDLSVNATLNYQFGVPLK
DQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLYVTLWLKADVTNEHPECVIKDTPEEAVGLEKCKWTINALINH
HYKIVAASWQVKNNAARTLVMPVIKENTLTEGNNNHWNLVLPAWQYSSDQAEQEKLNTWRVRLALEDEKGNRQSSGVVEI
TVQQDRKIELIVNNIANVPDKSNHSHEASAQADGVDGVVMDLDVTDRNGDALPEDNLTPQLYDAQDKRVTLTNKPCSTDN
PCVFIAKQDKEKGTVTLSSTLPGTYRWKAKAAPYDDSNYVDVTFLGAEIGGLNAFIYRVGAAKPSNLIGKDKEPLPLNNI
YRFVLWRDNNKDGVFQQVEKLTDEEMAQYDYKWEFTGKSINGEVDAQANTSNEDIVIPATNREAAQTYGAQAGDGLQGYG
LRVLYTKK

Specific function: Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 Big-1 (bacterial Ig-like domain 1) domains [H]

Homologues:

Organism=Escherichia coli, GI145693153, Length=418, Percent_Identity=36.3636363636364, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI145693120, Length=402, Percent_Identity=32.089552238806, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR016186
- InterPro:   IPR016187
- InterPro:   IPR003535
- InterPro:   IPR013117
- InterPro:   IPR008964
- InterPro:   IPR015217 [H]

Pfam domain/function: PF02369 Big_1; PF07979 Intimin_C; PF09134 Invasin_D3 [H]

EC number: NA

Molecular weight: Translated: 73025; Mature: 72893

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEALESQARSYLQSQITSTAQSYIEDTLSPYGKVRSNLSIGQGGDLDGSSIDYFVPWY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCEEEEEEEE
DNQTTVYFSQFSAQRKEDRTIGNIGLGVRYNFDKYLLGGNIFYDYDFTRGHRRLGLGAEA
CCCEEEEEEECCCCHHCCCCCCCEEEEEEECCCEEEECCEEEEEECCCCCCEEECCCHHH
WTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEAWLPAYPQLGGKIVFEQYYG
HHHHHHCCCCEECCCCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCCEEEEEEECC
NEVALFGTDSLEKDPFAVTLGVKYQPVPLIVVGTDFKAGTGDNTDLSVNATLNYQFGVPL
CEEEEEECCCCCCCCEEEEEECEECCEEEEEEECCCCCCCCCCCEEEEEEEEEEEECCCC
KDQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLYVTLWLKADVTNEHPECVIKD
CCCCCHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCEEEEC
TPEEAVGLEKCKWTINALINHHYKIVAASWQVKNNAARTLVMPVIKENTLTEGNNNHWNL
CCHHHCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCEEEE
VLPAWQYSSDQAEQEKLNTWRVRLALEDEKGNRQSSGVVEITVQQDRKIELIVNNIANVP
EEEEECCCCCHHHHHCCCEEEEEEEEECCCCCCCCCCEEEEEECCCCEEEEEEEHHHCCC
DKSNHSHEASAQADGVDGVVMDLDVTDRNGDALPEDNLTPQLYDAQDKRVTLTNKPCSTD
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCC
NPCVFIAKQDKEKGTVTLSSTLPGTYRWKAKAAPYDDSNYVDVTFLGAEIGGLNAFIYRV
CCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEE
GAAKPSNLIGKDKEPLPLNNIYRFVLWRDNNKDGVFQQVEKLTDEEMAQYDYKWEFTGKS
CCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCHHHHHHCCEEEEEECCC
INGEVDAQANTSNEDIVIPATNREAAQTYGAQAGDGLQGYGLRVLYTKK
CCCEEECCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
TPEALESQARSYLQSQITSTAQSYIEDTLSPYGKVRSNLSIGQGGDLDGSSIDYFVPWY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCEEEEEEEE
DNQTTVYFSQFSAQRKEDRTIGNIGLGVRYNFDKYLLGGNIFYDYDFTRGHRRLGLGAEA
CCCEEEEEEECCCCHHCCCCCCCEEEEEEECCCEEEECCEEEEEECCCCCCEEECCCHHH
WTDYLKFSGNYYHPLSDWKDSEDFDFYEERPARGWDIRAEAWLPAYPQLGGKIVFEQYYG
HHHHHHCCCCEECCCCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCCEEEEEEECC
NEVALFGTDSLEKDPFAVTLGVKYQPVPLIVVGTDFKAGTGDNTDLSVNATLNYQFGVPL
CEEEEEECCCCCCCCEEEEEECEECCEEEEEEECCCCCCCCCCCEEEEEEEEEEEECCCC
KDQLDPDKVSAAHSLMGSRHDFVERNNFIVLEYKEKDPLYVTLWLKADVTNEHPECVIKD
CCCCCHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCEEEEC
TPEEAVGLEKCKWTINALINHHYKIVAASWQVKNNAARTLVMPVIKENTLTEGNNNHWNL
CCHHHCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCEEEE
VLPAWQYSSDQAEQEKLNTWRVRLALEDEKGNRQSSGVVEITVQQDRKIELIVNNIANVP
EEEEECCCCCHHHHHCCCEEEEEEEEECCCCCCCCCCEEEEEECCCCEEEEEEEHHHCCC
DKSNHSHEASAQADGVDGVVMDLDVTDRNGDALPEDNLTPQLYDAQDKRVTLTNKPCSTD
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCC
NPCVFIAKQDKEKGTVTLSSTLPGTYRWKAKAAPYDDSNYVDVTFLGAEIGGLNAFIYRV
CCEEEEEECCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEE
GAAKPSNLIGKDKEPLPLNNIYRFVLWRDNNKDGVFQQVEKLTDEEMAQYDYKWEFTGKS
CCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCHHHHHHCCEEEEEECCC
INGEVDAQANTSNEDIVIPATNREAAQTYGAQAGDGLQGYGLRVLYTKK
CCCEEECCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3304658; 1693333; 10514372 [H]