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The map label for this gene is narP [H]

Identifier: 218690355

GI number: 218690355

Start: 2581716

End: 2582363

Strand: Direct

Name: narP [H]

Synonym: ECED1_2658

Alternate gene names: 218690355

Gene position: 2581716-2582363 (Clockwise)

Preceding gene: 218690353

Following gene: 218690371

Centisome position: 49.56

GC content: 52.31

Gene sequence:

>648_bases
ATGCCTGAAGCAACGCCTTTTCAGGTGATGATTGTGGATGATCATCCACTTATGCGACGCGGTGTTCGTCAGTTACTGGA
GCTTGATTCTGGCTTTGAAGTGGTCGCCGAAGCGGGCGACGGCGCAAGCGCGATCGATCTGGCGAATAGACTGGATATCG
ACGTGATCTTGCTGGATCTCAATATGAAAGGCATGAGTGGCCTGGATACCCTCAATGCCTTGCGCAGGGATGGCGTTACC
GCGCAAATTATTATCCTGACCGTATCAGATGCCTCCAGCGATGTCTTTGCACTGATAGACGCAGGCGCAGACGGTTATCT
GTTGAAAGACAGCGACCCGGAAGTGTTACTGGAAGCAATTCGTGCCGGAGCGAAAGGCAGCAAAGTCTTTAGCGAACGCG
TCAATCAGTACTTACGTGAACGTGAAATGTTTGGCGCGGAAGAAGACCCCTTCAGCGTGCTGACAGAACGCGAGCTGGAT
GTTCTGCACGAGCTGGCACAGGGGCTGTCAAATAAACAGATTGCCTCGGTGTTGAATATTTCCGAGCAGACAGTAAAAGT
CCATATTCGCAATCTGCTGCGTAAACTCAACGTCCGCTCACGCGTGGCGGCCACCATTCTGTTCCTGCAACAACGCGGGG
CACAATAA

Upstream 100 bases:

>100_bases
ACATGTCCATACATAAAATGGGGTAACATTCACGCGCCTGGTAGCGTTACCAACGCTACGCTCAAACATAATGATTCTAA
TAAAACCTCAGGAGACTACT

Downstream 100 bases:

>100_bases
AAATAGCCCGATGGCATCACCATCGGGCCACTTTTTATTTACTCTCCTGCGGCGACAAATGTTGCATCGCCTGCGCGATA
CTACGTTCGATCACCGCACG

Product: transcriptional regulator NarP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MPEATPFQVMIVDDHPLMRRGVRQLLELDSGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVT
AQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ

Sequences:

>Translated_215_residues
MPEATPFQVMIVDDHPLMRRGVRQLLELDSGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVT
AQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ
>Mature_214_residues
PEATPFQVMIVDDHPLMRRGVRQLLELDSGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVTA
QIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELDV
LHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ

Specific function: This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=215, Percent_Identity=99.0697674418605, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1787473, Length=214, Percent_Identity=43.9252336448598, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=32.0388349514563, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790102, Length=194, Percent_Identity=35.5670103092784, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=29, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1788712, Length=194, Percent_Identity=28.8659793814433, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1788546, Length=200, Percent_Identity=31, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1788191, Length=104, Percent_Identity=35.5769230769231, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23625; Mature: 23494

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEATPFQVMIVDDHPLMRRGVRQLLELDSGFEVVAEAGDGASAIDLANRLDIDVILLDL
CCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCEEEEEEEE
NMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAI
CCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHH
RAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELDVLHELAQGLSNKQIASVLNI
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PEATPFQVMIVDDHPLMRRGVRQLLELDSGFEVVAEAGDGASAIDLANRLDIDVILLDL
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCEEEEEEEE
NMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAI
CCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHH
RAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELDVLHELAQGLSNKQIASVLNI
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501030; 9278503 [H]