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The map label for this gene is yeiT [H]

Identifier: 218690295

GI number: 218690295

Start: 2517764

End: 2519002

Strand: Direct

Name: yeiT [H]

Synonym: ECED1_2593

Alternate gene names: 218690295

Gene position: 2517764-2519002 (Clockwise)

Preceding gene: 218690294

Following gene: 218690296

Centisome position: 48.33

GC content: 51.33

Gene sequence:

>1239_bases
ATGCCGCAACAAAATTATCTGGATGAACTCACTCCGGCTTTTACGCCTTTACTGGCGATTAAAGAAGCCTCTCGCTGTTT
ATTATGTCATGACGCTCCCTGTAGTCAGGCTTGCCCGGCACAGACCGATCCGGGGAAATTTATTCGCTCAATCTACTTTC
GTAATTTTAAAGGCGCTGCCGAGACAATTCGCGAAAATAATGCCCTCGGTGCCGTTTGTGCCAGAGTGTGCCCGACGGAG
AAATTATGCCAAAGCGGTTGTACACGTGCCGGTGTTGATGCTCCCATTGATATCGGTCGCTTACAGCGTTTTGTTACTGA
TTTTGAACAACAAACTGGGATGGAAATTTATCTGCCCGGTACTAAAACGCTCGGCAAAGTCGCCATTATTGGCGCAGGTC
CTGCCGGATTGCAGGCCAGTGTGACGCTGACAAACCAGGGTTATGACGTCACGATCTATGAGAAAGAAGCACAACCCGGT
GGCTGGTTGCGTAACGGCATTCCGCAATTCCGGTTACCGCAATCGGTGCTGGATGCAGAAATCGCCCGTATAGAAAAAAT
GGGCGTGACCATTAAGTGCAATAACGAAATCGGTAAAACACTCACCCTGGAGCAGCTGAAAGCGGAAAACCGCGCGGTAC
TGGTCACCGTAGGGTTATCGAGCGGTTCCGGGTTATCGCTGTTTGAGCATAGCGACGTTGAGATTGCCGTCGACTTCCTG
CAACGTGCACGACAGGCGCAAGGCGATATCAGCATTCCACAAAGCGCATTAATTATCGGCGGCGGTGATGTTGCGATGGA
CGTAGCCAGCACGCTGAAAGTTCTCGGCTGTCAGGCGGTAACCTGCGTAGCGCGTGAAGAGTTAGATGAGTTTCCGGCAA
GCGAAAAAGAGTTTACCAGCGCCAGAGAGCTGGGCGTTTCGATCATCGATGGATTTACACCAGTAGCCGTGGAAGGCAAT
AAAGTCACCTTTAAGCATGTTCGTTTACCGGGCGAACTGACGATGGCGGCAGATAAAATTATTCTCGCCGTCGGTCAGCA
TGCCAGACTGGATGCCTTTGCGGAGTTAGAGCCGCAGCGTAACACCATCGAAACGCAACATTACCAGACCCGCGACCCGC
AAGTCTTTGCTGCTGGCGATATTGTTGAGGGTGACAAAACCGTGGTCTATGCAGTGAAAACCGGGAAAGAAGCCGCCGGG
GCGATTCATCACTATTTAGAGGGAGCTTGCTCATGTTAA

Upstream 100 bases:

>100_bases
CTTTCACAGTTTAAATTTCCCCACGCGCATAGCCTTAATATCAGCACGCAATATTTATTTAGCGTTCGCCTTAATTACTC
ATAGCATTAAGGAAGATCAC

Downstream 100 bases:

>100_bases
CGAAAGATCTTTCGATTACTTTTTGCGGCGTGAAGTTTCCCAACCCGTTCTGCCTTTCTTCTTCGCCGGTAGGCAACTGC
TATGAGATGTGTGCCAAAGC

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MPQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDPGKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTE
KLCQSGCTRAGVDAPIDIGRLQRFVTDFEQQTGMEIYLPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAQPG
GWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEIGKTLTLEQLKAENRAVLVTVGLSSGSGLSLFEHSDVEIAVDFL
QRARQAQGDISIPQSALIIGGGDVAMDVASTLKVLGCQAVTCVAREELDEFPASEKEFTSARELGVSIIDGFTPVAVEGN
KVTFKHVRLPGELTMAADKIILAVGQHARLDAFAELEPQRNTIETQHYQTRDPQVFAAGDIVEGDKTVVYAVKTGKEAAG
AIHHYLEGACSC

Sequences:

>Translated_412_residues
MPQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDPGKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTE
KLCQSGCTRAGVDAPIDIGRLQRFVTDFEQQTGMEIYLPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAQPG
GWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEIGKTLTLEQLKAENRAVLVTVGLSSGSGLSLFEHSDVEIAVDFL
QRARQAQGDISIPQSALIIGGGDVAMDVASTLKVLGCQAVTCVAREELDEFPASEKEFTSARELGVSIIDGFTPVAVEGN
KVTFKHVRLPGELTMAADKIILAVGQHARLDAFAELEPQRNTIETQHYQTRDPQVFAAGDIVEGDKTVVYAVKTGKEAAG
AIHHYLEGACSC
>Mature_411_residues
PQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDPGKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEK
LCQSGCTRAGVDAPIDIGRLQRFVTDFEQQTGMEIYLPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAQPGG
WLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEIGKTLTLEQLKAENRAVLVTVGLSSGSGLSLFEHSDVEIAVDFLQ
RARQAQGDISIPQSALIIGGGDVAMDVASTLKVLGCQAVTCVAREELDEFPASEKEFTSARELGVSIIDGFTPVAVEGNK
VTFKHVRLPGELTMAADKIILAVGQHARLDAFAELEPQRNTIETQHYQTRDPQVFAAGDIVEGDKTVVYAVKTGKEAAGA
IHHYLEGACSC

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli glutamate synthase [NADPH] small chain (GltD) and to E.coli AegA [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=437, Percent_Identity=32.0366132723112, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI237757300, Length=90, Percent_Identity=48.8888888888889, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1788468, Length=412, Percent_Identity=97.5728155339806, Blast_Score=825, Evalue=0.0,
Organism=Escherichia coli, GI1788811, Length=446, Percent_Identity=32.5112107623318, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789606, Length=442, Percent_Identity=31.447963800905, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI87082180, Length=450, Percent_Identity=29.7777777777778, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1789243, Length=398, Percent_Identity=29.1457286432161, Blast_Score=136, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71984108, Length=439, Percent_Identity=33.0296127562642, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17570289, Length=449, Percent_Identity=28.0623608017817, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6320030, Length=461, Percent_Identity=25.3796095444685, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24640763, Length=434, Percent_Identity=31.1059907834101, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI18858217, Length=434, Percent_Identity=31.1059907834101, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24665547, Length=443, Percent_Identity=27.5395033860045, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24665543, Length=443, Percent_Identity=27.5395033860045, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI28574881, Length=443, Percent_Identity=27.5395033860045, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24665539, Length=443, Percent_Identity=27.5395033860045, Blast_Score=134, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR016040
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 44296; Mature: 44165

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDPGKFIRSIYFRNFKGAA
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHH
ETIRENNALGAVCARVCPTEKLCQSGCTRAGVDAPIDIGRLQRFVTDFEQQTGMEIYLPG
HHHHCCCCHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECC
TKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAQPGGWLRNGIPQFRLPQSVLDAE
CCCCCCEEEEECCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHCCCCCCCCCHHHHHHH
IARIEKMGVTIKCNNEIGKTLTLEQLKAENRAVLVTVGLSSGSGLSLFEHSDVEIAVDFL
HHHHHHHCEEEEECCCCCCEEEHHHHCCCCCEEEEEEECCCCCCCEEEECCCHHHHHHHH
QRARQAQGDISIPQSALIIGGGDVAMDVASTLKVLGCQAVTCVAREELDEFPASEKEFTS
HHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ARELGVSIIDGFTPVAVEGNKVTFKHVRLPGELTMAADKIILAVGQHARLDAFAELEPQR
HHHCCHHHCCCCCCEEEECCEEEEEEEECCCCHHHHHCEEEEEECCCCCCCHHHHCCCCC
NTIETQHYQTRDPQVFAAGDIVEGDKTVVYAVKTGKEAAGAIHHYLEGACSC
CCCCCCCCCCCCCEEEEECCEECCCCEEEEEEECCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDPGKFIRSIYFRNFKGAA
CCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHH
ETIRENNALGAVCARVCPTEKLCQSGCTRAGVDAPIDIGRLQRFVTDFEQQTGMEIYLPG
HHHHCCCCHHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECC
TKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAQPGGWLRNGIPQFRLPQSVLDAE
CCCCCCEEEEECCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHCCCCCCCCCHHHHHHH
IARIEKMGVTIKCNNEIGKTLTLEQLKAENRAVLVTVGLSSGSGLSLFEHSDVEIAVDFL
HHHHHHHCEEEEECCCCCCEEEHHHHCCCCCEEEEEEECCCCCCCEEEECCCHHHHHHHH
QRARQAQGDISIPQSALIIGGGDVAMDVASTLKVLGCQAVTCVAREELDEFPASEKEFTS
HHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ARELGVSIIDGFTPVAVEGNKVTFKHVRLPGELTMAADKIILAVGQHARLDAFAELEPQR
HHHCCHHHCCCCCCEEEECCEEEEEEEECCCCHHHHHCEEEEEECCCCCCCHHHHCCCCC
NTIETQHYQTRDPQVFAAGDIVEGDKTVVYAVKTGKEAAGAIHHYLEGACSC
CCCCCCCCCCCCCEEEEECCEECCCCEEEEEEECCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]