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The map label for this gene is nhoA [H]

Identifier: 218689386

GI number: 218689386

Start: 1595938

End: 1596783

Strand: Direct

Name: nhoA [H]

Synonym: ECED1_1616

Alternate gene names: 218689386

Gene position: 1595938-1596783 (Clockwise)

Preceding gene: 218689384

Following gene: 218689394

Centisome position: 30.63

GC content: 50.35

Gene sequence:

>846_bases
ATGACGCCCATTCTGAATCATTATTTTGCCCGTATTAACTGGTTGGGAGCTGCTGCGGCCAATATTGATACGCTGCGTGC
ATTGCACCTGAAACACAATTGCACCATTCCGTTTGAAAATCTCGACGTTTTGCTGCCGAGGGAAATACAGCTTGATGATC
AATCGCTGGAAGATAAACTGGTGATAGCCCGTCGTGGCGGTTACTGTTTTGAGCAGAATGGCGTGTTTGAGCGGGTGTTA
CGCGAGCTGGGGTTTAACGTTCGCAGCTTGTTAGGTCGCGTAGTGTTATCAAATCCGCCAGCATTACCGCCGCGCACCCA
TCGTTTGCTGTTGGTGGAACTGGAAGGGGAAAAATGGATTGCTGATGTCGGTTTCGGTGGGCAGACGCTAACCGCGCCGA
TTCGTTTAATGCCGGATATCATGCAAACCACGCCACACGGAGAGTATCGGTTGTTGCAAGAGGGTGATGATTGGGTATTG
CAGTTTAATCATCATCAGCACTGGCAGTCGATGTACCGTTTTGATCTCTGCGAGCAGCAACAAAGCGATTATGTGATGGG
CAATTTCTGGTCGGCGCACTGGCCGCAGTCGCATTTTCGCCATCATTTGCTGATGTGTCGCCATTTGCCGGACGGTGGCA
AGCTAACGCTGACCAATTTTCATTTTACCCATTATGAAAATGGGCACGCAGTTGAGCAGCGAAATCTACCAGATGTGGCG
TCGTTATATGCCGTGATGCAGGAACAGTTTGGTCTGGGCGTAGATGATGCGAAACATGGCTTTACTGTGGATGAGTTAGC
GCTGGTGATGGCGGCGTTTGATACGCACCCGGAGGCGGGAAAATAA

Upstream 100 bases:

>100_bases
GCGATTTGCGAACGTGATGCATGTCCGCGATCGCACAAAATAGCCAGTGCGGCGTCTATTCCAGGTTATAAGTTGAGAAA
ACCACTAAGGGAAACGCCTG

Downstream 100 bases:

>100_bases
TTTATGTCAGGTTGCCGGATGTGGCGTAAATGCCTTATCCGGCCTACATTAGCCCGGTTGTAGACCTGATAAGCGAAGCG
CATCAGGCAACGGCATCAAA

Product: N-hydroxyarylamine O-acetyltransferase

Products: NA

Alternate protein names: Arylamine N-acetyltransferase; Arylhydroxamate N,O-acetyltransferase; NAT102 [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEDKLVIARRGGYCFEQNGVFERVL
RELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVL
QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK

Sequences:

>Translated_281_residues
MTPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEDKLVIARRGGYCFEQNGVFERVL
RELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVL
QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
>Mature_280_residues
TPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEDKLVIARRGGYCFEQNGVFERVLR
ELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVLQ
FNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVAS
LYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK

Specific function: Unknown

COG id: COG2162

COG function: function code Q; Arylamine N-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arylamine N-acetyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI237649132, Length=290, Percent_Identity=24.4827586206897, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649130, Length=290, Percent_Identity=24.4827586206897, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649128, Length=284, Percent_Identity=24.2957746478873, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649126, Length=284, Percent_Identity=24.2957746478873, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649124, Length=284, Percent_Identity=24.2957746478873, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649122, Length=284, Percent_Identity=24.2957746478873, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649119, Length=284, Percent_Identity=24.2957746478873, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI42741671, Length=284, Percent_Identity=24.2957746478873, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649009, Length=284, Percent_Identity=24.2957746478873, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787736, Length=281, Percent_Identity=96.44128113879, Blast_Score=550, Evalue=1e-158,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001447 [H]

Pfam domain/function: PF00797 Acetyltransf_2 [H]

EC number: =2.3.1.118 [H]

Molecular weight: Translated: 32278; Mature: 32147

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEDKL
CCCHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCCEECCCEECCCCCCCCCEE
VIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWI
EEEECCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEE
ADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVLQFNHHQHWQSMYRFDLCEQQ
EECCCCCCEEEHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
QSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
CCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHH
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEDKL
CCHHHHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCCEECCCEECCCCCCCCCEE
VIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWI
EEEECCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEE
ADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVLQFNHHQHWQSMYRFDLCEQQ
EECCCCCCEEEHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
QSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
CCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHH
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]