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The map label for this gene is ydcR [H]

Identifier: 218689367

GI number: 218689367

Start: 1574260

End: 1575666

Strand: Direct

Name: ydcR [H]

Synonym: ECED1_1593

Alternate gene names: 218689367

Gene position: 1574260-1575666 (Clockwise)

Preceding gene: 218689365

Following gene: 218689368

Centisome position: 30.22

GC content: 50.68

Gene sequence:

>1407_bases
ATGAAAAAATACCAGCAGCTTGCAGAACAATTACGCGAGCAGATTGCGTCGGGTATCTGGCAACCCGGCGATCGTTTGCC
TTCGTTGCGTGACCAGGTGGCGCTTTCTGGCATGAGCTTTATGACTGTCAGCCATGCCTATCAGTTGCTCGAAAGTCAGG
GATATATTATCGCGCGACCGCAATCGGGTTATTACGTTGCGCCACAGGCAATAAAAATGCCGAAAGCGACAGTCATTCCA
GTCACACGAGATGAAGCAGTCGATATCAACACCTATATTTTTGATATGTTGCAGGCCAGTCGCGATCCGTCGGTAGTTCC
GTTTGCCTCGGCCTTTCCCGACCCGCGACTTTTCCCCCTCCAACAACTAAACCGCTCGCTGGCGCAGGTAAGCAAAACCG
CCACGGCGATGAGCGTGATTGAAAACTTACCGCCAGGAAACGTAGAACTGCGTCAGGCTATTGCTCGTCGCTATGCCTTA
CAGGGCATCACCATTTCTCCTGATGAAATTGTCATTACCGCCGGGGCGTTAGAGGCATTAAACCTCAGTTTGCAAGCGGT
AACTGAACCGGGCTATTGGGTGATAGTAGAGAATCCTTGTTTCTACGGCGCGTTGCAGGCGCTGGAGCGGTTACGGCTGA
AGGCGTTATCGGTAGCGACGGATATTAAAGAAGGGATCGATCTTCAGGCGCTGGAACTGGCGTTGCAGGAGTATCCGGTG
AAAGCGTGCTGGCTGATGACTAATAGCCAGAACCCACTTGGATTTACCTTAACGCCGCAGAAAAAAGTGCGGCTGGTAGC
GTTGCTCAATCAGTACAACGTAACGCTGATTGAAGATGACGTTTATAGCGAACTTTATTTTGGACGGGAAAAACCGCTGC
CTGCGAAAGCGTGGGATCGCCACGATGGTGTTTTGCATTGCTCTTCGTTTTCGAAATGTCTGGTGCCTGGTTTTCGTATT
GGTTGGGTCGCCGCCGGAAAACATGCACGTAAAATTCAACGCTTGCAGTTGATGAGTACGCTTTCCACCAGCTCACCGAT
GCAGCTTGCGCTGGTGGATTACCTTTCTACTCGCCGATACGATGCTCATCTTCGTCGTCTGCGTCGCCAGCTTGCGGAAC
GTAAACAACACGCCTGGCAGGCTTTGCTGCGTTATCTGCCTGCGGAAGTCAAAATTCATCACAATGACAGCGGTTATTTT
CTCTGGCTGGAGCTCCCCGAGCCGTTAGATGCAGGAGAATTAAGCCTGGTGGCACTGACGCATCATATCAGTATTGCGCC
GGGTAATATGTTTTCTACCGGTGAAAACTGGTCACGTTTTTTTCGTTTTAATACCGCGTGGCAGTGGGGAGAACGTGAAG
AACAGGCGGTAAAACAATTAGGCAAACTTATTCAAGAACGGCTGTAA

Upstream 100 bases:

>100_bases
GTTATCGCTGGTGATGGTTTAATTACAGTTAACGAAAAGTTGTCATTTTTAACAACTGATATAGACTGCCGAATCATCTG
CACATAATTACGATTCGATA

Downstream 100 bases:

>100_bases
TAGCGTTTAATTTAATTCCTCTCAGGTTGGGTAATATGAATTTCGAATAGCAGTCATATATCCTAACTCCTTGTCTATAC
TCCAGAAGATAACCTTACAG

Product: putative DNA-binding transcriptional regulator fused with a domain with PLP-binding motif

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKATVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNVELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGYWVIVENPCFYGALQALERLRLKALSVATDIKEGIDLQALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKVRLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQHAWQALLRYLPAEVKIHHNDSGYF
LWLELPEPLDAGELSLVALTHHISIAPGNMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL

Sequences:

>Translated_468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKATVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNVELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGYWVIVENPCFYGALQALERLRLKALSVATDIKEGIDLQALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKVRLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQHAWQALLRYLPAEVKIHHNDSGYF
LWLELPEPLDAGELSLVALTHHISIAPGNMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL
>Mature_468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKATVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNVELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGYWVIVENPCFYGALQALERLRLKALSVATDIKEGIDLQALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKVRLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQHAWQALLRYLPAEVKIHHNDSGYF
LWLELPEPLDAGELSLVALTHHISIAPGNMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=401, Percent_Identity=25.6857855361596, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI33469970, Length=401, Percent_Identity=25.6857855361596, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4507369, Length=236, Percent_Identity=24.1525423728814, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI1787710, Length=468, Percent_Identity=98.0769230769231, Blast_Score=944, Evalue=0.0,
Organism=Escherichia coli, GI1790797, Length=469, Percent_Identity=34.9680170575693, Blast_Score=292, Evalue=3e-80,
Organism=Escherichia coli, GI1788722, Length=374, Percent_Identity=24.5989304812834, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=189, Percent_Identity=25.3968253968254, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356535, Length=331, Percent_Identity=24.4712990936556, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI18859735, Length=219, Percent_Identity=28.310502283105, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52939; Mature: 52939

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECC
QSGYYVAPQAIKMPKATVIPVTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPL
CCCEEECCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEHHCCCCCCCCCH
QQLNRSLAQVSKTATAMSVIENLPPGNVELRQAIARRYALQGITISPDEIVITAGALEAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHH
NLSLQAVTEPGYWVIVENPCFYGALQALERLRLKALSVATDIKEGIDLQALELALQEYPV
CCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KACWLMTNSQNPLGFTLTPQKKVRLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDR
EEEEEEECCCCCCEEEECCHHHHHHEEEHHHCCEEEEECHHHHHHHCCCCCCCCCCCCCC
HDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRY
CCCEEEECCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHH
DAHLRRLRRQLAERKQHAWQALLRYLPAEVKIHHNDSGYFLWLELPEPLDAGELSLVALT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCEEEEEEE
HHISIAPGNMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL
EEEEECCCCCCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECC
QSGYYVAPQAIKMPKATVIPVTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPL
CCCEEECCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEHHCCCCCCCCCH
QQLNRSLAQVSKTATAMSVIENLPPGNVELRQAIARRYALQGITISPDEIVITAGALEAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHH
NLSLQAVTEPGYWVIVENPCFYGALQALERLRLKALSVATDIKEGIDLQALELALQEYPV
CCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KACWLMTNSQNPLGFTLTPQKKVRLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDR
EEEEEEECCCCCCEEEECCHHHHHHEEEHHHCCEEEEECHHHHHHHCCCCCCCCCCCCCC
HDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRY
CCCEEEECCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHH
DAHLRRLRRQLAERKQHAWQALLRYLPAEVKIHHNDSGYFLWLELPEPLDAGELSLVALT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCEEEEEEE
HHISIAPGNMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL
EEEEECCCCCCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]