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The map label for this gene is emrK [H]

Identifier: 218689327

GI number: 218689327

Start: 1519788

End: 1520819

Strand: Direct

Name: emrK [H]

Synonym: ECED1_1548

Alternate gene names: 218689327

Gene position: 1519788-1520819 (Clockwise)

Preceding gene: 218689321

Following gene: 218689328

Centisome position: 29.17

GC content: 46.22

Gene sequence:

>1032_bases
GTGATGATAATTTCTAAAAAACAGCTTATTGGGGTGGTAGCGATCGGTATTCTTTTGGCTGGCGTTGTCTTTTTTATCTG
GTGGGTAAGCAAAGGAAGATTTATACAGACGACGGATGATGCTTACATTGGTGGTAATATCACCACGGTGGCAAGTAAAG
TTTCTGGTTATATTTCTGCTATAGAGGTGCGCGATAATCAGAGTGTAAAAAAAGGCGATATTATCCTGCGTCTCGATGAT
CGGGATTATCGTGCAAATGTCGCCAGGCTTGAGGCAAAAATAAAAAGTAGCAAAGCCAATCTCGAAAGCATTCAAGCCAC
TATTGCGATGCAGCAGTCGATAATTCAAAGTGCCAGTGAAACATGGCAGGCAGTAAAACATGAGGAGCAAAAGCGCCTGC
GAGATACTGAACGTTATGAAAAACTCGCACAATCAGCGGCAATATCGCAACAAATTATTGATAACGCCAGGTTTGACTAC
CAGCAGGTCGCAGCAAAGGAGCGCAAAGCCGCGAACGATTTCCTGGTGGAGAAGCAACGGCTGGCAGTTTTATCTGCTCA
GGAAGAAAACGTACGTACAAGTATCGAAGAAGTTCAGGCCGCTTTGACTCAGGCACTACTGGATCTGGAATATACCCTTG
TTCGTGCGCCGATTGATGGCATTGTCGCAAACCGCAGCGCCCATACAGGCAGTTGGGTGGAAGGCGGCACATCGTTAGTT
TCACTAGTACCAGTCAGTGAGTTGTGGGTTGATGCAAATTATAAAGAAAACCAAATAGCGGGAATGAAGCCAGGAATGAA
GGCTGAGATCCGTGCTGATATTCTCAAAGGGGAAGTGTTTCACGGTCACATTGAAAGCCTTTCCCCAGCGACAGGAGCCA
GTTTCAGCTTGATTCCGATAGAAAATGCCACTGGCAATTTCACCAAAATTGTTCAGCGTGTCCCGGTACGGATTGCATTT
GACGACGCAAAGGAATTAAAGCAACTTCTTCGCCCCGGACTGTCCGTCACCGTCAGTGTTGATGAGAGATGA

Upstream 100 bases:

>100_bases
TTGTCATTTACAGTAGGTATTTTGTCAGAAATCATCAAATAAGCCATGTTAAATTTTAAATATGACGTATGCAAGTTTCC
GGATATATACGGTGTAAAGA

Downstream 100 bases:

>100_bases
TGTCTATGCGTAAACATATTGCTTTCGCCAGTATGTGTATGGGATTATTTATTGCTCAGCTTGATATTCAAATTGTATCG
TCATCCCTAAATGAAATAGG

Product: putative HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MMIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGGNITTVASKVSGYISAIEVRDNQSVKKGDIILRLDD
RDYRANVARLEAKIKSSKANLESIQATIAMQQSIIQSASETWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDY
QQVAAKERKAANDFLVEKQRLAVLSAQEENVRTSIEEVQAALTQALLDLEYTLVRAPIDGIVANRSAHTGSWVEGGTSLV
SLVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATGASFSLIPIENATGNFTKIVQRVPVRIAF
DDAKELKQLLRPGLSVTVSVDER

Sequences:

>Translated_343_residues
MMIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGGNITTVASKVSGYISAIEVRDNQSVKKGDIILRLDD
RDYRANVARLEAKIKSSKANLESIQATIAMQQSIIQSASETWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDY
QQVAAKERKAANDFLVEKQRLAVLSAQEENVRTSIEEVQAALTQALLDLEYTLVRAPIDGIVANRSAHTGSWVEGGTSLV
SLVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATGASFSLIPIENATGNFTKIVQRVPVRIAF
DDAKELKQLLRPGLSVTVSVDER
>Mature_343_residues
MMIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGGNITTVASKVSGYISAIEVRDNQSVKKGDIILRLDD
RDYRANVARLEAKIKSSKANLESIQATIAMQQSIIQSASETWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDY
QQVAAKERKAANDFLVEKQRLAVLSAQEENVRTSIEEVQAALTQALLDLEYTLVRAPIDGIVANRSAHTGSWVEGGTSLV
SLVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATGASFSLIPIENATGNFTKIVQRVPVRIAF
DDAKELKQLLRPGLSVTVSVDER

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=341, Percent_Identity=31.0850439882698, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789041, Length=334, Percent_Identity=31.1377245508982, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1790519, Length=325, Percent_Identity=26.7692307692308, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790024, Length=293, Percent_Identity=25.938566552901, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789637, Length=345, Percent_Identity=27.2463768115942, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1790012, Length=243, Percent_Identity=27.1604938271605, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87081951, Length=317, Percent_Identity=25.5520504731861, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37879; Mature: 37879

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGGNITTVASKVSGYISA
CEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHHHHHHHEEE
IEVRDNQSVKKGDIILRLDDRDYRANVARLEAKIKSSKANLESIQATIAMQQSIIQSASE
EEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
TWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQQVAAKERKAANDFLVEKQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LAVLSAQEENVRTSIEEVQAALTQALLDLEYTLVRAPIDGIVANRSAHTGSWVEGGTSLV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCHHE
SLVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATGASFSLIPI
EEEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCHHHHCCCCCCCCEEEEEE
ENATGNFTKIVQRVPVRIAFDDAKELKQLLRPGLSVTVSVDER
CCCCCHHHHHHHHCCCEEEECCHHHHHHHHCCCCEEEEEECCC
>Mature Secondary Structure
MMIISKKQLIGVVAIGILLAGVVFFIWWVSKGRFIQTTDDAYIGGNITTVASKVSGYISA
CEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHHHHHHHEEE
IEVRDNQSVKKGDIILRLDDRDYRANVARLEAKIKSSKANLESIQATIAMQQSIIQSASE
EEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
TWQAVKHEEQKRLRDTERYEKLAQSAAISQQIIDNARFDYQQVAAKERKAANDFLVEKQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LAVLSAQEENVRTSIEEVQAALTQALLDLEYTLVRAPIDGIVANRSAHTGSWVEGGTSLV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCHHE
SLVPVSELWVDANYKENQIAGMKPGMKAEIRADILKGEVFHGHIESLSPATGASFSLIPI
EEEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCHHHHCCCCCCCCEEEEEE
ENATGNFTKIVQRVPVRIAFDDAKELKQLLRPGLSVTVSVDER
CCCCCHHHHHHHHCCCEEEECCHHHHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]