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The map label for this gene is hinT [H]

Identifier: 218689055

GI number: 218689055

Start: 1247866

End: 1248225

Strand: Direct

Name: hinT [H]

Synonym: ECED1_1246

Alternate gene names: 218689055

Gene position: 1247866-1248225 (Clockwise)

Preceding gene: 218689053

Following gene: 218689056

Centisome position: 23.95

GC content: 50.28

Gene sequence:

>360_bases
GTGGCAGAAGAAACTATATTCAGCAAAATTATTCGTCGTGAGATCCCCTCCGATATCGTCTACCAGGATGATCTGGTAAC
GGCGTTTCGCGATATTTCGCCGCAAGCGCCAACGCATATTCTGATCATTCCGAATATCCTCATTCCGACTGTGAACGACG
TGTCAGCTGAGCATGAGCAGGCGCTGGGACGCATGATCACCGTAGCGGCAAAAATTGCTGAGCAAGAAGGTATTGCCGAA
GATGGCTATCGTCTGATCATGAACACCAACCGCCATGGCGGACAAGAGGTTTACCACATCCATATGCATTTGTTGGGTGG
CTGTCCGCTGGGACCAATGCTGGCGCATAAAGGTCTGTAA

Upstream 100 bases:

>100_bases
AAGGTTGAAAGAGCAGGTTTAACTCGACCATACTCTATACTCGCAGTGTGGCGCGGCGTAGCATGGCGCAACGCATGGCT
ATTTGAAAAAGGAAAATGTC

Downstream 100 bases:

>100_bases
CGATGAGAAAAGGATGCTTTGGGCTGATGTCTCTGGCGTTGTTAGTGCTGGTGGGCTGTCGTTCACATCCGGAAATTCCG
GTGAATGATGAGCAATCGCT

Product: purine nucleoside phosphoramidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAE
DGYRLIMNTNRHGGQEVYHIHMHLLGGCPLGPMLAHKGL

Sequences:

>Translated_119_residues
MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAE
DGYRLIMNTNRHGGQEVYHIHMHLLGGCPLGPMLAHKGL
>Mature_118_residues
AEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAED
GYRLIMNTNRHGGQEVYHIHMHLLGGCPLGPMLAHKGL

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI14211923, Length=106, Percent_Identity=46.2264150943396, Blast_Score=111, Evalue=1e-25,
Organism=Homo sapiens, GI4885413, Length=104, Percent_Identity=48.0769230769231, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787346, Length=119, Percent_Identity=99.1596638655462, Blast_Score=239, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17506713, Length=109, Percent_Identity=43.1192660550459, Blast_Score=107, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28574010, Length=106, Percent_Identity=45.2830188679245, Blast_Score=109, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24581222, Length=106, Percent_Identity=45.2830188679245, Blast_Score=109, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 13188; Mature: 13057

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVSAEHEQ
CCHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCCCCEEEEEECCEECCCCCCCCHHHHH
ALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGCPLGPMLAHKGL
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEHHHCCCCCCHHHHCCCC
>Mature Secondary Structure 
AEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVSAEHEQ
CHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCCCCEEEEEECCEECCCCCCCCHHHHH
ALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHMHLLGGCPLGPMLAHKGL
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEHHHCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]