Click here to switch to the map view.

The map label for this gene is pqiA

Identifier: 218688786

GI number: 218688786

Start: 1009201

End: 1010454

Strand: Direct

Name: pqiA

Synonym: ECED1_0973

Alternate gene names: 218688786

Gene position: 1009201-1010454 (Clockwise)

Preceding gene: 218688785

Following gene: 218688787

Centisome position: 19.37

GC content: 51.91

Gene sequence:

>1254_bases
ATGTGCGAACATCATCATGCCGCGAAGCACATCCTGTGCTCGCAGTGTGACATGCTGGTGGCGTTACCGCGCCTTGAGCA
TGGTCAGAAAGCGGCATGTCCCCGGTGTGGCACAACGTTAACCGTGGCGTGGGATGCCCCTCGGCAGCGTCCCACCGCCT
ATGCGTTGGCTGCACTGTTCATGCTGTTGCTGTCCAACTTGTTTCCTTTTGTGAATATGAACGTTGCAGGAGTTACCAGT
GAAATTACATTACTGGAAATTCCCGGCGTGCTTTTTTCTGAGGACTACGCCAGCCTCGGCACCTTTTTCCTGTTGTTTGT
GCAACTGGTTCCCGCGTTTTGTCTGATAACCATTCTGTTACTGGTGAATCGCGCGGAATTACCGGTCCGTTTAAAAGAGC
AACTGGCACGGGTGCTTTTTCAACTCAAAACCTGGGGAATGGCGGAGATTTTCCTCGCGGGTGTGCTGGTCAGTTTCGTT
AAACTGATGGCTTACGGCAGCATTGGGGTAGGCAGCAGCTTTCTCCCCTGGTGTTTATTTTGTGTCCTGCAACTGCGCGC
TTTTCAGTGCGTTGATCGTCGCTGGTTATGGGACGACATCGCCCCAATGCCAGAACTGCGCCAGCCGCTAAAACCAGGTG
TCACGGGGATACGTCAGGGGCTGCGTTCGTGCTCCTGTTGTACGGCAATCCTTCCTGCTGATGAACCCGTGTGCCCGCGT
TGTAGTACCAAAGGGTACGTTCGGCGTAGAAACAGCCTGCAGTGGACACTCGCGCTGCTTGTAACGTCCATCATGCTGTA
TCTTCCGGCTAATATTTTGCCCATCATGGTGACGGATTTATTAGGCTCGAAGATGCCGTCGACGATTCTCGCTGGGGTCA
TTCTGTTATGGAGCGAAGGCTCTTATCCCGTCGCTGCGGTGATTTTTCTGGCCAGTATTATGGTGCCAACGTTAAAGATG
ATCGCCATTGCGTGGCTGTGTTGGGATGCCAAAGGACACGGCAAGCGCGACAGTGAAAGAATGCATTTGATTTATGAAGT
TGTTGAGTTTGTAGGCCGCTGGTCGATGATTGACGTTTTCGTTATCGCGGTGCTCTCGGCGCTGGTGCGTATGGGAGGTT
TAATGAGTATTTATCCGGCAATGGGTGCATTAATGTTTGCTTTAGTCGTCATAATGACAATGTTTTCTGCTATGACGTTT
GACCCGCGTTTGTCGTGGGATCGTCAACCTGAATCAGAGCATGAGGAGTCCTGA

Upstream 100 bases:

>100_bases
GCTGACAACGGTAAAATTGCCTGATGAACTGGGTTTATCAGGCATGAAAACCAACACTTTGTTAGTCATCTGCAAAATAG
CGCATCATTAAGGAGTACCA

Downstream 100 bases:

>100_bases
CAGTATGGAATCTAATAATGGGGAAGCCAAAATCCAGAAAGTGAAGAACTGGTCTCCCGTGTGGATATTTCCTATCGTCA
CGGCGCTCATTGGGGCCTGG

Product: paraquat-inducible membrane protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAWDAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTS
EITLLEIPGVLFSEDYASLGTFFLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIRQGLRSCSCCTAILPADEPVCPR
CSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIMVTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKM
IAIAWLCWDAKGHGKRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIMTMFSAMTF
DPRLSWDRQPESEHEES

Sequences:

>Translated_417_residues
MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAWDAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTS
EITLLEIPGVLFSEDYASLGTFFLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIRQGLRSCSCCTAILPADEPVCPR
CSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIMVTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKM
IAIAWLCWDAKGHGKRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIMTMFSAMTF
DPRLSWDRQPESEHEES
>Mature_417_residues
MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAWDAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTS
EITLLEIPGVLFSEDYASLGTFFLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIRQGLRSCSCCTAILPADEPVCPR
CSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIMVTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKM
IAIAWLCWDAKGHGKRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIMTMFSAMTF
DPRLSWDRQPESEHEES

Specific function: Unknown

COG id: COG2995

COG function: function code S; Uncharacterized paraquat-inducible protein A

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pqiA family

Homologues:

Organism=Escherichia coli, GI1787183, Length=417, Percent_Identity=100, Blast_Score=849, Evalue=0.0,
Organism=Escherichia coli, GI1788137, Length=397, Percent_Identity=29.4710327455919, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PQIA_ECOL6 (P0AFM0)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_753011.1
- ProteinModelPortal:   P0AFM0
- EnsemblBacteria:   EBESCT00000045331
- GeneID:   1035761
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c1086
- GeneTree:   EBGT00050000011519
- HOGENOM:   HBG303313
- OMA:   MIDIFVI
- ProtClustDB:   PRK15103
- InterPro:   IPR005219
- InterPro:   IPR007498
- TIGRFAMs:   TIGR00155

Pfam domain/function: PF04403 PqiA

EC number: NA

Molecular weight: Translated: 46464; Mature: 46464

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f9e0b84)-; HASH(0x1fed4fd0)-; HASH(0x1fd446cc)-; HASH(0x1ee25ff0)-; HASH(0x1f5a4df4)-; HASH(0x1eac14c4)-; HASH(0x1f9a17a0)-; HASH(0x1e11c9b8)-;

Cys/Met content:

3.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAWDAPRQRPTAYALAALF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHH
MLLLSNLFPFVNMNVAGVTSEITLLEIPGVLFSEDYASLGTFFLLFVQLVPAFCLITILL
HHHHHHHCHHHCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFVKLMAYGSIGVGSSFLPWCLF
HHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
CVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIRQGLRSCSCCTAILPADEPVCPR
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
CSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIMVTDLLGSKMPSTILAGVILLWSEG
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
SYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHGKRDSERMHLIYEVVEFVGRWSMIDVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
VIAVLSALVRMGGLMSIYPAMGALMFALVVIMTMFSAMTFDPRLSWDRQPESEHEES
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAWDAPRQRPTAYALAALF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHH
MLLLSNLFPFVNMNVAGVTSEITLLEIPGVLFSEDYASLGTFFLLFVQLVPAFCLITILL
HHHHHHHCHHHCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFVKLMAYGSIGVGSSFLPWCLF
HHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
CVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIRQGLRSCSCCTAILPADEPVCPR
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
CSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIMVTDLLGSKMPSTILAGVILLWSEG
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
SYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHGKRDSERMHLIYEVVEFVGRWSMIDVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
VIAVLSALVRMGGLMSIYPAMGALMFALVVIMTMFSAMTFDPRLSWDRQPESEHEES
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157