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The map label for this gene is mukE [H]

Identifier: 218688766

GI number: 218688766

Start: 980185

End: 980862

Strand: Direct

Name: mukE [H]

Synonym: ECED1_0953

Alternate gene names: 218688766

Gene position: 980185-980862 (Clockwise)

Preceding gene: 218688765

Following gene: 218688767

Centisome position: 18.82

GC content: 52.36

Gene sequence:

>678_bases
ATGCCGGTTAAGCTGGCGCAGGCGCTGGCGAATCCGTTATTTCCGGCGCTGGATAGCGCCTTACGTTCAGGCCGTCATAT
TGGCCTCGACGAACTGGATAATCATGCATTCCTGATGGATTTTCAGGAATATCTGGAAGAGTTTTACGCGCGTTATAACG
TTGAGCTTATTCGTGCACCGGAAGGGTTCTTCTATCTACGCCCACGTTCCACCACGCTGATCCCTCGTTCCGTCTTGTCG
GAACTGGATATGATGGTCGGGAAAATCCTCTGTTATCTCTATCTCAGCCCGGAACGGCTGGCGAATGAGGGGATTTTTAC
TCAACAGGAACTGTACGACGAACTGCTCACCCTGGCCGATGAAGCGAAACTGCTGAAACTGGTGAACAACCGTTCAACCG
GTTCAGACGTTGACCGTCAGAAGTTGCAGGAAAAAGTACGTTCTTCGCTCAACCGTCTGCGTCGTTTAGGCATGGTGTGG
TTTATGGGCCACGACAGCAGCAAGTTCCGCATTACCGAATCGGTGTTCCGCTTCGGAGCCGATGTGCGTGCTGGCGACGA
TCCCCGTGAAGCACAGCGTCGCCTGATTCGTGACGGCGAAGCAATGCCGATTGAAAATCATCTGCAACTCAACGATGAAA
CCGAAGAGAGTCAGCCAGATAGCGGAGAGGAAGAATAA

Upstream 100 bases:

>100_bases
GCGCAAGCAGATTTCACCGGACTGCCAGCGAAATGGCAGCCGATTAATGATTACGGAGCCAAGGTACAGGCGCATGTCAT
CGACAAATATTGAACAAGTG

Downstream 100 bases:

>100_bases
TGATTGAACGCGGTAAATTTCGCTCACTGACGCTGATTAACTGGAACGGCTTTTTTGCCCGAACTTTTGACCTTGACGAG
CTGGTCACGACGCTTTCTGG

Product: condesin subunit E

Products: NA

Alternate protein names: Protein kicA [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MPVKLAQALANPLFPALDSALRSGRHIGLDELDNHAFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLS
ELDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLNRLRRLGMVW
FMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQLNDETEESQPDSGEEE

Sequences:

>Translated_225_residues
MPVKLAQALANPLFPALDSALRSGRHIGLDELDNHAFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLS
ELDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLNRLRRLGMVW
FMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQLNDETEESQPDSGEEE
>Mature_224_residues
PVKLAQALANPLFPALDSALRSGRHIGLDELDNHAFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSE
LDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLNRLRRLGMVWF
MGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQLNDETEESQPDSGEEE

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interactio

COG id: COG3095

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukE family [H]

Homologues:

Organism=Escherichia coli, GI226510932, Length=225, Percent_Identity=99.5555555555556, Blast_Score=459, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007385 [H]

Pfam domain/function: PF04288 MukE [H]

EC number: NA

Molecular weight: Translated: 25958; Mature: 25827

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVKLAQALANPLFPALDSALRSGRHIGLDELDNHAFLMDFQEYLEEFYARYNVELIRAP
CCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCEEEECC
EGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLAD
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
EAKLLKLVNNRSTGSDVDRQKLQEKVRSSLNRLRRLGMVWFMGHDSSKFRITESVFRFGA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCC
DVRAGDDPREAQRRLIRDGEAMPIENHLQLNDETEESQPDSGEEE
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PVKLAQALANPLFPALDSALRSGRHIGLDELDNHAFLMDFQEYLEEFYARYNVELIRAP
CHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCEEEECC
EGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLAD
CCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
EAKLLKLVNNRSTGSDVDRQKLQEKVRSSLNRLRRLGMVWFMGHDSSKFRITESVFRFGA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCC
DVRAGDDPREAQRRLIRDGEAMPIENHLQLNDETEESQPDSGEEE
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7513784; 8905232; 9278503; 1989883; 8602138 [H]