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The map label for this gene is allB [H]

Identifier: 218688370

GI number: 218688370

Start: 553338

End: 554699

Strand: Direct

Name: allB [H]

Synonym: ECED1_0531

Alternate gene names: 218688370

Gene position: 553338-554699 (Clockwise)

Preceding gene: 218688369

Following gene: 218688371

Centisome position: 10.62

GC content: 51.69

Gene sequence:

>1362_bases
ATGTCTTTTGATTTAATCATTAAAAACGGCACCGTTATTTTAGAAAACGAAGCTCGCGTTGTAGATATCGCCGTTAAAGA
CGGAAAAATTGCTGCTATCGGCCAGGATCTGGGCGATGCAAAAGACGTTATGGATGCGTCTGGTCTGGTGGTTTCGCCGG
GCATGGTTGATGCGCACACCCATATTTCTGAACCGGGTCGCAGCCACTGGGAAGGTTATGAAACCGGTACTCGCGCAGCA
GCAAAAGGTGGTATCACCACCATGATCGAAATGCCGCTCAACCAGCTGCCTGCAACGGTTGACCGCGCCTCAATTGAACT
GAAGTTCGATGCCGCTAAAGGAAAGCTGACTATCGATGCGGCACAACTCGGTGGCCTGGTGTCTTACAACATTGACCGTC
TGCATGAGTTGGATGAAGTGGGTGTTGTCGGTTTCAAATGCTTCGTTGCGACCTGTGGCGATCGCGGTATCGACAACGAC
TTCCGTGACGTCAATGACTGGCAATTCTTCAAAGGCGCGCAGAAGCTGGGTGAACTAGGCCAGCCGGTGCTGGTGCACTG
CGAAAACGCGCTGATCTGTGACGCACTGGGCGAAGAAGCGAAGCGTGAAGGTCGCGTAACTGCCCATGACTATGTGGCTT
CGCGTCCGGTATTTACCGAAGTGGAAGCGATTCGCCGCGTACTGTACCTGGCGAAAGTCGCTGGTTGCCGTCTGCACGTT
TGCCACGTCAGCAGCCCGGAAGGTGTTGAGGAAGTGACTCGTGCACGTCAGGAAGGTCAGGATGTTACTTGTGAATCCTG
CCCGCATTACTTTGTGCTGGATACCGATCAGTTCGAAGAAATCGGTACTCTGGCGAAGTGTTCACCGCCGATCCGCGATC
TGGAAAACCAGAAAGGCATGTGGGAAAAACTGTTTAACGGTGAAATAGACTGCCTGGTTTCCGACCACTCTCCATGCCCG
CCGGAAATGAAAGCCGGTAACATCATGAAAGCGTGGGGCGGTATCGCTGGTCTGCAAAGCTGCATGGACGTGATGTTCGA
TGAAGCGGTACAGAAACGCGGAATGTCTCTGCCAATGTTCGGCAAATTAATGGCGACTAACGCAGCAGATATTTTCGGTC
TGCAGCAAAAAGGCCGTATCGCCCCAGGAAAAGATGCCGACTTCGTCTTCATTCAGCCGAATAGCAGCTATGTTCTTACC
AATGACGATCTGGAATATCGCCACAAAGTCAGCCCGTATGTTGGCCGTACTATTGGCGCGCGTATCACGAAAACCATCTT
ACGTGGTGATGTGATTTACGATATCGAACAGGGCTTCCCTGTTGCGCCGAAAGGTCAATTTATCCTTAAACATCAGCAGT
AA

Upstream 100 bases:

>100_bases
CAACAGCAGAAAAAACAGGAGAACAAAAAACCATAGGTTAATTAATCACGATATTGAACATTGAGTTAAAAACCAATCTG
TATTTTACAAGGAGTTTGTT

Downstream 100 bases:

>100_bases
TCTGGCCCTGCAATGCCCGTCCTTGTGGCGGGCATTCTCCGGTTAAGGTGTGTTTATGTTCAATTTTGCAGTGGGCCGCG
AAAGCCTGTTATCAGGATTT

Product: allantoinase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSFDLIIKNGTVILENEARVVDIAVKDGKIAAIGQDLGDAKDVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAA
AKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
FRDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
CHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCP
PEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLT
NDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ

Sequences:

>Translated_453_residues
MSFDLIIKNGTVILENEARVVDIAVKDGKIAAIGQDLGDAKDVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAA
AKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
FRDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
CHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCP
PEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLT
NDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ
>Mature_452_residues
SFDLIIKNGTVILENEARVVDIAVKDGKIAAIGQDLGDAKDVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAA
KGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDF
RDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVC
HVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPP
EMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTN
DDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503375, Length=469, Percent_Identity=27.9317697228145, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI4503379, Length=477, Percent_Identity=26.4150943396226, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI4503051, Length=418, Percent_Identity=28.9473684210526, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI62422571, Length=420, Percent_Identity=28.5714285714286, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI18105007, Length=422, Percent_Identity=24.1706161137441, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4503377, Length=431, Percent_Identity=27.6102088167053, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19923821, Length=456, Percent_Identity=26.3157894736842, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI190194363, Length=433, Percent_Identity=28.4064665127021, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1786722, Length=453, Percent_Identity=99.3377483443709, Blast_Score=933, Evalue=0.0,
Organism=Escherichia coli, GI87082175, Length=444, Percent_Identity=29.5045045045045, Blast_Score=170, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17539558, Length=469, Percent_Identity=27.2921108742004, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71989490, Length=471, Percent_Identity=26.963906581741, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI193204318, Length=392, Percent_Identity=24.4897959183673, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI86575075, Length=439, Percent_Identity=24.373576309795, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322218, Length=469, Percent_Identity=32.8358208955224, Blast_Score=252, Evalue=9e-68,
Organism=Drosophila melanogaster, GI18859883, Length=430, Percent_Identity=34.4186046511628, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI221377917, Length=470, Percent_Identity=27.2340425531915, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI17137462, Length=465, Percent_Identity=26.6666666666667, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24642586, Length=399, Percent_Identity=24.0601503759398, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24644287, Length=304, Percent_Identity=27.6315789473684, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24644289, Length=263, Percent_Identity=26.9961977186312, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 49588; Mature: 49457

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDLIIKNGTVILENEARVVDIAVKDGKIAAIGQDLGDAKDVMDASGLVVSPGMVDAHT
CCEEEEEECCEEEEECCCEEEEEEECCCEEEEECCCCCCHHHHHCCCCEEECCCCCCCCC
HISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDA
CCCCCCCHHCCCCCCCCHHHHCCCCEEEEECCHHHCCCCCCCEEEEEEEECCCCEEEEEH
AQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELG
HHHCCEEEECHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCC
QPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
CCEEEEECCEEEEHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEE
CHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGM
EECCCCCCHHHHHHHHHCCCCCCHHCCCCEEEECCHHHHHHCCHHHCCCCHHHHHCCCCH
WEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMF
HHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGA
HHHHHCCCHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCHHHHCCCHHHHHHHHH
RITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ
HHHHHHHCCCEEEEECCCCCCCCCCCEEEECCC
>Mature Secondary Structure 
SFDLIIKNGTVILENEARVVDIAVKDGKIAAIGQDLGDAKDVMDASGLVVSPGMVDAHT
CEEEEEECCEEEEECCCEEEEEEECCCEEEEECCCCCCHHHHHCCCCEEECCCCCCCCC
HISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDA
CCCCCCCHHCCCCCCCCHHHHCCCCEEEEECCHHHCCCCCCCEEEEEEEECCCCEEEEEH
AQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELG
HHHCCEEEECHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCC
QPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
CCEEEEECCEEEEHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEE
CHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGM
EECCCCCCHHHHHHHHHCCCCCCHHCCCCEEEECCHHHHHHCCHHHCCCCHHHHHCCCCH
WEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMF
HHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGA
HHHHHCCCHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCHHHHCCCHHHHHHHHH
RITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ
HHHHHHHCCCEEEEECCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA