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The map label for this gene is mhpF [H]

Identifier: 218688222

GI number: 218688222

Start: 400050

End: 401000

Strand: Direct

Name: mhpF [H]

Synonym: ECED1_0379

Alternate gene names: 218688222

Gene position: 400050-401000 (Clockwise)

Preceding gene: 218688221

Following gene: 218688223

Centisome position: 7.68

GC content: 55.31

Gene sequence:

>951_bases
ATGAGTAAGCGTAAAGTCGCCATTATCGGTTCTGGCAACATTGGCACCGATCTGATGATTAAAATTTTGCGTCACGGTCA
GCATCTGGAGATGGCGGTGATGGTCGGCATTGATCCTCAGTCCGACGGTCTGGCGCGTGCCAGACGTATGGGCGTCGCCA
CCACCCATGAAGGGGTGATCGGGCTGATGAACATGCCTGAATTTGCTGATATCGACATTGTATTTGATGCGACCAGCGCG
GGCGCGCATGTGAAAAACGATGCCGCTTTGCGCGAAGCGAAACCGGATATTCGCTTAATTGACCTGACGCCTGCTGCCAT
CGGCCCTTACTGCGTGCCGGTGGTTAACCTCGAGGAGAACGTCGATCAACTGAACGTCAACATGGTCACCTGCGGCGGCC
AGGCCACCATTCCAATGGTGGCGGCAGTTTCACGCGTGGCGCGTGTTCATTACGCCGAAATTATCGCTTCTATCGCCAGT
AAATCTGCCGGACCTGGCACGCGTGCCAATATCGATGAATTTACGGAAACCACTTCCCGAGCCATTGAAGTGGTGGGCGG
CGCGGCGAAAGGGAAGGCGATTATCGTGCTTAACCCAGCAGAGCCACCGTTGATGATGCGTGACACGGTGTATGTATTGA
GCGACGAAGCTTCACAAGATGATATCGAAGCCTCAATCAATGAAATGGCTGAGGCGGTGCAGGCTTACGTACCGGGATAT
CGCCTGAAACAGCGCGTGCAGTTTGAAGTTATCCCGCAGGATAAACCGGTTAATTTGCCGGGCGTGGGGCAGTTCTCCGG
GCTGAAAACGGCGGTCTGGCTGGAAGTCGAAGGCGCAGCGCATTATCTGTCTGCCTATGCGGGCAACCTCGACATTATGA
CTTCCAGTGCGCTGGCGACAGCGGAAAAAATGGCCCAGTCACTGGCGCGCAAGGCAGGAGAAGCGGCATGA

Upstream 100 bases:

>100_bases
TGGTGGCGGTGAATGCGGGCGATCGTTTTGAAGCCCATATTGAAGGCATAGGTTCAGTTGCTGCGACATTTTCAAGCGCA
GCCCCAAAAGGAAGTCTGTC

Downstream 100 bases:

>100_bases
ACGGTAAAAAACTTTATATTTCGGACGTCACGTTGCGTGACGGTATGCACGCCATTCGTCATCAGTATTCGCTGGAAAAT
GTCCGCCAGATTGCCAAAGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSA
GAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEENVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIAS
KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGY
RLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLSAYAGNLDIMTSSALATAEKMAQSLARKAGEAA

Sequences:

>Translated_316_residues
MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSA
GAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEENVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIAS
KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGY
RLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLSAYAGNLDIMTSSALATAEKMAQSLARKAGEAA
>Mature_315_residues
SKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAG
AHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEENVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIASK
SAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGYR
LKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLSAYAGNLDIMTSSALATAEKMAQSLARKAGEAA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds [H]

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786547, Length=316, Percent_Identity=99.3670886075949, Blast_Score=638, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.10 [H]

Molecular weight: Translated: 33491; Mature: 33360

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVI
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCEE
GLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEEN
EECCCCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCC
VDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIASKSAGPGTRANIDEFTETTSR
CCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGY
HHHHHCCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCH
RLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLSAYAGNLDIMTSSALAT
HHHCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCEEEEEHHHHHH
AEKMAQSLARKAGEAA
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVI
CCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCEE
GLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEEN
EECCCCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCC
VDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIASKSAGPGTRANIDEFTETTSR
CCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGY
HHHHHCCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCH
RLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLSAYAGNLDIMTSSALAT
HHHCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCEEEEEHHHHHH
AEKMAQSLARKAGEAA
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA