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The map label for this gene is hexR [C]

Identifier: 218688144

GI number: 218688144

Start: 310012

End: 310845

Strand: Direct

Name: hexR [C]

Synonym: ECED1_0293

Alternate gene names: 218688144

Gene position: 310012-310845 (Clockwise)

Preceding gene: 218688143

Following gene: 218688145

Centisome position: 5.95

GC content: 47.72

Gene sequence:

>834_bases
ATGTCTAAACATCAAACTCAACTTTCCTTACTGCAGGATGATATCCGCAGTCGCTATGATAGCCTTAGCAAACGTCTTAA
ACAAGTTGCTCAGTATATACTGGATAACAGTAATAGCGTTGCTTTTGATACGGTCGCTTCCATCGCGCAACATGCCGATG
TTCCCCCTTCGACACTGATTCGTTTTGCTAATGCGTTTGGTTTTAGCGGATTTAATGAAATGAAACGGATATTTCGCCAG
CACCTGATGGAGGAAACAGTAAGCTATACCGAGCGGGCGCGTCTGTTCAGACAGAAAAATGCGGATGAAGGGGAACCTAC
CCCGGAAAAGCCGGGTGAAATTCTGAAGCTATTTTCAATGGTGAATGCACAGGTATTACAACAATTACCGGTGCAGATTA
AAAATGAGCAGTTGGATGCGGCGGTAAATCTGTTAGCGAAAGCTGACAATATTTATGTGATTGGATTACGTCGTTCGTTT
AGCGTGGCCAGTTATTTAACCTACGCATTGCGTCATCTGGAGAGACGGGCATTTTTAATTGACGGTATTGGCGGAATGTT
CTCTGAACAGCTAAGTATGGTCAGCTCCGACGATGTCGTTATTGCCATCAGCTACTCGCCTTACGCGCAGGAAGTGGTGG
AATTAGTCGAGCTTGGCGCGAAACGCGGTGCGCACTATATTGCGATAACCGATAGCCAGGTCAGCCCGCTGGCAGCGTTC
AGTGAAGTCTGTTTTGTGGTACGTGAAGCGCAGGTCGATGGTTTCCGTTCTCAGGTCGCGTCCATGTGTCTGGCGCAAAC
GTTAGCGGTTTCACTGGCGCTGGCGACGGAGTAA

Upstream 100 bases:

>100_bases
TAGTTGGGTAATCAGTTGCCGATTCAACTTAACTGTATGTTCAGTTCATTTGTGATAATATGGTTATTTCCGAAATTTTC
GTTCCATTAGAGTATCATGC

Downstream 100 bases:

>100_bases
AAAAAGGGAGCGGTTTGGGAAACGGAATTTTTTGTTAAGCGAATTATTTAATCAATTTTAGATCCTAACGTATTGATTTA
ACGTCAGTGGCTATCGCCTT

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSKHQTQLSLLQDDIRSRYDSLSKRLKQVAQYILDNSNSVAFDTVASIAQHADVPPSTLIRFANAFGFSGFNEMKRIFRQ
HLMEETVSYTERARLFRQKNADEGEPTPEKPGEILKLFSMVNAQVLQQLPVQIKNEQLDAAVNLLAKADNIYVIGLRRSF
SVASYLTYALRHLERRAFLIDGIGGMFSEQLSMVSSDDVVIAISYSPYAQEVVELVELGAKRGAHYIAITDSQVSPLAAF
SEVCFVVREAQVDGFRSQVASMCLAQTLAVSLALATE

Sequences:

>Translated_277_residues
MSKHQTQLSLLQDDIRSRYDSLSKRLKQVAQYILDNSNSVAFDTVASIAQHADVPPSTLIRFANAFGFSGFNEMKRIFRQ
HLMEETVSYTERARLFRQKNADEGEPTPEKPGEILKLFSMVNAQVLQQLPVQIKNEQLDAAVNLLAKADNIYVIGLRRSF
SVASYLTYALRHLERRAFLIDGIGGMFSEQLSMVSSDDVVIAISYSPYAQEVVELVELGAKRGAHYIAITDSQVSPLAAF
SEVCFVVREAQVDGFRSQVASMCLAQTLAVSLALATE
>Mature_276_residues
SKHQTQLSLLQDDIRSRYDSLSKRLKQVAQYILDNSNSVAFDTVASIAQHADVPPSTLIRFANAFGFSGFNEMKRIFRQH
LMEETVSYTERARLFRQKNADEGEPTPEKPGEILKLFSMVNAQVLQQLPVQIKNEQLDAAVNLLAKADNIYVIGLRRSFS
VASYLTYALRHLERRAFLIDGIGGMFSEQLSMVSSDDVVIAISYSPYAQEVVELVELGAKRGAHYIAITDSQVSPLAAFS
EVCFVVREAQVDGFRSQVASMCLAQTLAVSLALATE

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30820; Mature: 30688

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHQTQLSLLQDDIRSRYDSLSKRLKQVAQYILDNSNSVAFDTVASIAQHADVPPSTLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHH
RFANAFGFSGFNEMKRIFRQHLMEETVSYTERARLFRQKNADEGEPTPEKPGEILKLFSM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
VNAQVLQQLPVQIKNEQLDAAVNLLAKADNIYVIGLRRSFSVASYLTYALRHLERRAFLI
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
DGIGGMFSEQLSMVSSDDVVIAISYSPYAQEVVELVELGAKRGAHYIAITDSQVSPLAAF
HCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
SEVCFVVREAQVDGFRSQVASMCLAQTLAVSLALATE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKHQTQLSLLQDDIRSRYDSLSKRLKQVAQYILDNSNSVAFDTVASIAQHADVPPSTLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHH
RFANAFGFSGFNEMKRIFRQHLMEETVSYTERARLFRQKNADEGEPTPEKPGEILKLFSM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
VNAQVLQQLPVQIKNEQLDAAVNLLAKADNIYVIGLRRSFSVASYLTYALRHLERRAFLI
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
DGIGGMFSEQLSMVSSDDVVIAISYSPYAQEVVELVELGAKRGAHYIAITDSQVSPLAAF
HCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
SEVCFVVREAQVDGFRSQVASMCLAQTLAVSLALATE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]