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The map label for this gene is crl [H]

Identifier: 218688132

GI number: 218688132

Start: 292724

End: 293125

Strand: Direct

Name: crl [H]

Synonym: ECED1_0274

Alternate gene names: 218688132

Gene position: 292724-293125 (Clockwise)

Preceding gene: 218688131

Following gene: 218688134

Centisome position: 5.62

GC content: 50.25

Gene sequence:

>402_bases
ATGACGTTACCGAGTGGACACCCGAAGAGCAGATTAGTCAAAAAATTTACCGCACTAGGCCCGTATATTCGTGAAGGTAA
GTGCGAAGATAATCGATTCTTTTTCGATTGTCTGGCTGTATGCGTCAACGTGAAACCGGCACCGGAAGTGCGTGAGTTCT
GGGGCTGGTGGATGGAACTGGAAGCGCAGGAATCCCGTTTTACCTACAGTTACCAGTTTGGTCTGTTCGATAAAGCAGGC
GACTGGACGAGTGTTCAGATAAAAGATGCCGAAGTGGTTGAACGACTGGAGCACACCCTGCGTGAATTTCACGAGAAGCT
GCGTGAGCTGCTGGCGACGCTGAATCTGAAGCTGGAACCGGCAGATGATTTTCGTGATGAACCGGTGAAGTTAACGGCGT
GA

Upstream 100 bases:

>100_bases
CCTTCAGGAAATCACAGACTGGATCGAAAAACGTTTGTGTTAAAAATTTGCTAAATTTTACCAATTTGGTAAAACAGTTG
CATCACAACAGGAGATTGCA

Downstream 100 bases:

>100_bases
ATGAAATGTGCCGGATGCATCACATCCGGCAATATCCATTAAAACTGATAGGTCATGCCAACCGCGACAATATCATCATT
ATTAATATTCAATTTGTTAT

Product: DNA-binding transcriptional regulator Crl

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MTLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAG
DWTSVQIKDAEVVERLEHTLREFHEKLRELLATLNLKLEPADDFRDEPVKLTA

Sequences:

>Translated_133_residues
MTLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAG
DWTSVQIKDAEVVERLEHTLREFHEKLRELLATLNLKLEPADDFRDEPVKLTA
>Mature_132_residues
TLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGD
WTSVQIKDAEVVERLEHTLREFHEKLRELLATLNLKLEPADDFRDEPVKLTA

Specific function: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the crl family [H]

Homologues:

Organism=Escherichia coli, GI1786435, Length=133, Percent_Identity=94.7368421052632, Blast_Score=265, Evalue=7e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009986 [H]

Pfam domain/function: PF07417 Crl [H]

EC number: NA

Molecular weight: Translated: 15600; Mature: 15469

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMEL
CCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEE
EAQESRFTYSYQFGLFDKAGDWTSVQIKDAEVVERLEHTLREFHEKLRELLATLNLKLEP
ECCCCEEEEEEEECCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ADDFRDEPVKLTA
CCCCCCCCEEECC
>Mature Secondary Structure 
TLPSGHPKSRLVKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMEL
CCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEE
EAQESRFTYSYQFGLFDKAGDWTSVQIKDAEVVERLEHTLREFHEKLRELLATLNLKLEP
ECCCCEEEEEEEECCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ADDFRDEPVKLTA
CCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA