| Definition | Escherichia coli ED1a chromosome, complete genome. |
|---|---|
| Accession | NC_011745 |
| Length | 5,209,548 |
Click here to switch to the map view.
The map label for this gene is ldcC [H]
Identifier: 218688061
GI number: 218688061
Start: 214453
End: 216594
Strand: Direct
Name: ldcC [H]
Synonym: ECED1_0192
Alternate gene names: 218688061
Gene position: 214453-216594 (Clockwise)
Preceding gene: 218688060
Following gene: 218688062
Centisome position: 4.12
GC content: 51.45
Gene sequence:
>2142_bases ATGAACATCATTGCCATTATGGGACCGCATGGCGTCTTTTATAAAGATGAGCCCATCAAAGAACTGGAGTCGGCGCTGGT GGCGCAAGGCTTTCAGATTATCTGGCCACAAAACAGCGTTGATTTGCTGAAGTTTATCGAACATAACCCACGAATTTGCG GCGTGATTTTTGACTGGGATGAGTACAGTCTCGATTTATGTAGCGATATCAATCAACTTAATGAATATCTCCCGCTTTAT GCCTTCATCAACACCCACTCGACGATGGATGTCAGCGTGCAGGATATGCGGATGGCGCTCTGGTTTTTTGAATATGCGCT GGGGCAGGCGGAAGATATCGCCATTCGTATGCGTCAGTGCACCAACGAATATCTTGATAACATTACGCCGCCGTTCACGA AAGCCTTGTTTACCTACGTCAAAGAGCGGAAGTACACCTTTTGTACGCCGGGGCATATGGGCGGCACCGCATATCAAAAA AGCCCGGTTGGCTGTCTGTTTTATGATTTTTTCGGCGGGAATACCCTCAAGGCGGACGTCTCTATTTCGGTCACCGAGCT TGGTTCGTTGCTCGACCACACCGGGCCACACCTGGAAGCGGAAGAGTACATCGCGCGGACGTTTGGCGCGGAACAGAGTT ATATCGTTACCAACGGAACATCGACGTCGAACAAAATTGTGGGTATGTACGCCGCGCCATCCGGCAGTACGCTGTTGATC GACCGCAATTGTCATAAATCGCTGGCGCATCTGTTGATGATGAACGATGTAGTGCCAGTCTGGCTGAAACCGACGCGTAA TGCGTTGGGGATTCTGGGTGGGATCCCGCGCGGTGAATTTACTCGCGACAGCATCGAAGAGAAAGTCGCTGCCACCACGC AGGCACAATGGCCGGTTCATGCGGTGATCACCAACTCCACCTATGATGGCTTGCTCTACAACACCGACTGGATCAAACAG ACGCTGGATGTCCCGTCGATTCACTTCGATTCTGCCTGGGTGCCGTACACCCATTTTCATCCGATCTACCAGGGTAAAAG TGGTATGAGCGGCGAGCGTGTTGCGGGAAAAGTGATCTTCGAAACGCAATCTACCCACAAAATGCTGGCGGCGTTATCGC AGGCTTCGCTGATCCACATTAAAGGCGAGTATGACGAGGAGGCGTTTAACGAAGCCTTTATGATGCATACCACCACCTCG CCCAGTTATCCCATTGTTGCTTCGGTTGAGACGGCGGCGGCGATGCTGCGTGGTAATCCTGGCAAACGGCTGATTAACCG TTCAGTAGAACGAGCTCTGCATTTTCGCAAAGAGGTCCAGCGGCTGCGGGAAGAGTCTGACGGCTGGTTTTTTGATATCT GGCAACCGCCGCAGGTGGATGAAGCCGAATGCTGGCCCGTTGCGCCTGGCGAACAGTGGCACGGCTTTAGCGATGCGGAT GCCAATCACATGTTTCTCGATCCGGTTAAAGTCACTATTTTGACACCGGGGATGGACGAGCAGGGCAATATGAGCGAGGA GGGGATCCCGGCGGCGCTGGTGGCAAAATTCCTCGACGAACGTGGGATCGTAGTAGAGAAAACTGGCCCTTATAACCTGC TGTTTCTCTTTAGTATTGGCATCGATAAAACCAAAGCAATGGGATTATTGCGTGGGTTGACGGAATTTAAGCGCTCTTAC GATCTCAACCTGAGGATCAAAAATATGCTACCCGACCTCTATGCAGAAGATCCCGATTTCTACCGCAATATGCGTATTCA GGATCTGGCGCAAGGGATCCATAAGCTGATTCGTAAACACGATCTTCCCGGTTTGATGTTGCGGGCATTTGATACCTTGC CGGAGATGATCATGACGCCACATCAGGCATGGCAGAGACAGATTAAAGGCGAAGTAGAAACCATTGCGCTGGAACAACTG GTCGGTAGGGTGTCGGCAAATATGATCCTGCCTTATCCACCCGGCGTACCGCTGCTGATGCCGGGAGAAATGCTTACCGA AGAGAGCCGCACGGTACTCGATTTTCTACTGATGCTTTGTTCCGTAGGGCAACATTACCCCGGTTTTGAAACGGATATTC ACGGCGCGAAACAGGACGAAGACGGTGTTTACCGCGTACGAGTCCTAAAAATGGCAGGATAA
Upstream 100 bases:
>100_bases TAATCGGCAAATGTTCTGAAAAGGGTCACTTCGGTGGCCCTTTTTTATCGCCACGGTTTGAGCAGGCTATGATTAAGGAA GGATTTTCCAGGAGGAACAC
Downstream 100 bases:
>100_bases CTTGCCAGAGCGGCTTCCGGGCGAGTAACGTGCTGTTAACAAATAAAGGAGACGTTATGCTGGGTTTAAAACAGGTTCAC CATATTGCGATTATTGCGAC
Product: lysine decarboxylase 2
Products: NA
Alternate protein names: LDC [H]
Number of amino acids: Translated: 713; Mature: 713
Protein sequence:
>713_residues MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLKFIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLY AFINTHSTMDVSVQDMRMALWFFEYALGQAEDIAIRMRQCTNEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTNGTSTSNKIVGMYAAPSGSTLLI DRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIPRGEFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQ TLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEAFMMHTTTS PSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWFFDIWQPPQVDEAECWPVAPGEQWHGFSDAD ANHMFLDPVKVTILTPGMDEQGNMSEEGIPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSY DLNLRIKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAWQRQIKGEVETIALEQL VGRVSANMILPYPPGVPLLMPGEMLTEESRTVLDFLLMLCSVGQHYPGFETDIHGAKQDEDGVYRVRVLKMAG
Sequences:
>Translated_713_residues MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLKFIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLY AFINTHSTMDVSVQDMRMALWFFEYALGQAEDIAIRMRQCTNEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTNGTSTSNKIVGMYAAPSGSTLLI DRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIPRGEFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQ TLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEAFMMHTTTS PSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWFFDIWQPPQVDEAECWPVAPGEQWHGFSDAD ANHMFLDPVKVTILTPGMDEQGNMSEEGIPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSY DLNLRIKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAWQRQIKGEVETIALEQL VGRVSANMILPYPPGVPLLMPGEMLTEESRTVLDFLLMLCSVGQHYPGFETDIHGAKQDEDGVYRVRVLKMAG >Mature_713_residues MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLKFIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLY AFINTHSTMDVSVQDMRMALWFFEYALGQAEDIAIRMRQCTNEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTNGTSTSNKIVGMYAAPSGSTLLI DRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIPRGEFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQ TLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEAFMMHTTTS PSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWFFDIWQPPQVDEAECWPVAPGEQWHGFSDAD ANHMFLDPVKVTILTPGMDEQGNMSEEGIPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSY DLNLRIKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAWQRQIKGEVETIALEQL VGRVSANMILPYPPGVPLLMPGEMLTEESRTVLDFLLMLCSVGQHYPGFETDIHGAKQDEDGVYRVRVLKMAG
Specific function: LDC is constitutively but weakly expressed under various conditions [H]
COG id: COG1982
COG function: function code E; Arginine/lysine/ornithine decarboxylases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]
Homologues:
Organism=Escherichia coli, GI1786384, Length=713, Percent_Identity=99.1584852734923, Blast_Score=1477, Evalue=0.0, Organism=Escherichia coli, GI1790573, Length=710, Percent_Identity=69.4366197183099, Blast_Score=1089, Evalue=0.0, Organism=Escherichia coli, GI221142684, Length=735, Percent_Identity=35.1020408163265, Blast_Score=460, Evalue=1e-130, Organism=Escherichia coli, GI87082193, Length=629, Percent_Identity=33.5453100158983, Blast_Score=326, Evalue=2e-90, Organism=Escherichia coli, GI1786909, Length=692, Percent_Identity=31.3583815028902, Blast_Score=304, Evalue=2e-83,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005308 - InterPro: IPR011193 - InterPro: IPR000310 - InterPro: IPR008286 - InterPro: IPR015424 - InterPro: IPR015421 - InterPro: IPR015422 [H]
Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]
EC number: =4.1.1.18 [H]
Molecular weight: Translated: 80404; Mature: 80404
Theoretical pI: Translated: 5.23; Mature: 5.23
Prosite motif: PS00703 OKR_DC_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 5.2 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 4.1 %Met (Mature Protein) 5.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLKFIEHNPRICGVIFDWD CCEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCEEEEEECCC EYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWFFEYALGQAEDIAIRMRQC CCCHHHHHHHHHHHHHCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHH TNEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQKSPVGCLFYDFFGGNTLKADV HHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEE SISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTNGTSTSNKIVGMYAAPSGSTLLI EEEHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCEEEE DRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIPRGEFTRDSIEEKVAATTQAQWPVH ECCHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEE AVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERVAGKVIF EEEECCCCCCEEEEHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE ETQSTHKMLAALSQASLIHIKGEYDEEAFNEAFMMHTTTSPSYPIVASVETAAAMLRGNP ECCHHHHHHHHHCCCCEEEEECCCCHHHHCCEEEEEECCCCCCCEEEEHHHHHHHHCCCC GKRLINRSVERALHFRKEVQRLREESDGWFFDIWQPPQVDEAECWPVAPGEQWHGFSDAD HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC ANHMFLDPVKVTILTPGMDEQGNMSEEGIPAALVAKFLDERGIVVEKTGPYNLLFLFSIG CCCEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCEEEEEEEEC IDKTKAMGLLRGLTEFKRSYDLNLRIKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKH CCHHHHHHHHHHHHHHHHCCCCCEEEHHHCCHHHCCCCHHHHCCCHHHHHHHHHHHHHHC DLPGLMLRAFDTLPEMIMTPHQAWQRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLM CCCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEE PGEMLTEESRTVLDFLLMLCSVGQHYPGFETDIHGAKQDEDGVYRVRVLKMAG CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECC >Mature Secondary Structure MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLKFIEHNPRICGVIFDWD CCEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCEEEEEECCC EYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWFFEYALGQAEDIAIRMRQC CCCHHHHHHHHHHHHHCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHH TNEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQKSPVGCLFYDFFGGNTLKADV HHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEE SISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTNGTSTSNKIVGMYAAPSGSTLLI EEEHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCEEEE DRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIPRGEFTRDSIEEKVAATTQAQWPVH ECCHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEE AVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERVAGKVIF EEEECCCCCCEEEEHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE ETQSTHKMLAALSQASLIHIKGEYDEEAFNEAFMMHTTTSPSYPIVASVETAAAMLRGNP ECCHHHHHHHHHCCCCEEEEECCCCHHHHCCEEEEEECCCCCCCEEEEHHHHHHHHCCCC GKRLINRSVERALHFRKEVQRLREESDGWFFDIWQPPQVDEAECWPVAPGEQWHGFSDAD HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC ANHMFLDPVKVTILTPGMDEQGNMSEEGIPAALVAKFLDERGIVVEKTGPYNLLFLFSIG CCCEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCEEEEEEEEC IDKTKAMGLLRGLTEFKRSYDLNLRIKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKH CCHHHHHHHHHHHHHHHHCCCCCEEEHHHCCHHHCCCCHHHHCCCHHHHHHHHHHHHHHC DLPGLMLRAFDTLPEMIMTPHQAWQRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLM CCCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEE PGEMLTEESRTVLDFLLMLCSVGQHYPGFETDIHGAKQDEDGVYRVRVLKMAG CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9226257; 9339543; 9278503; 9723924 [H]