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The map label for this gene is yaaU [H]

Identifier: 218687921

GI number: 218687921

Start: 47442

End: 48773

Strand: Direct

Name: yaaU [H]

Synonym: ECED1_0044

Alternate gene names: 218687921

Gene position: 47442-48773 (Clockwise)

Preceding gene: 218687920

Following gene: 218687922

Centisome position: 0.91

GC content: 53.53

Gene sequence:

>1332_bases
ATGCAACCGTCCAGAAACTTTGATGATCTTAAATTCTCCTCTATTCACCGCCGCATTTTGCTGTGGGGAAGCGGTGGTCC
GTTTCTGGATGGTTATGTACTGGTAATGATTGGCGTGGCGCTGGAGCAACTGACTCCGGCGCTGAAACTGGACGCTGACT
GGATTGGCTTGCTGGGCGCGGGAACGCTCGCCGGGCTGTTCGTTGGCACATCGCTGTTTGGCTATATCTCCGATAAAGTC
GGACGGCGCAAAATGTTCCTCATTGATATCATCGCCATCGGCGTGATATCGGTGGCGACGATGTTTGTCTCATCCCCCGT
CGAACTGTTGGTGATGCGGGTACTTATCGGCATTGTTATCGGTGCGGATTATCCTATCGCCACCTCAATGATCACCGAGT
TCTCCAGTACCCGTCAGCGGGCGTTTTCCATCAGCTTTATCGCCGCGATGTGGTATGTCGGCGCGACCTGCGCCGATTTG
GTCGGCTATTGGCTTTATGATGTGGAAGGCGGCTGGCGCTGGATGCTGGGTAGCGCAGCGATTCCCTGTTTGTTGATTTT
GATTGGTCGATTCGAACTGCCTGAATCTCCCCGCTGGTTGTTACGCAAAGGGCGAGTAAAAGAGTGCGAAGAGATGATGA
TAAAACTGTTTGGCGAACCGGTGGCTTTCGAGGAAGAGCAGCCGCAGCAAACCCGTTTTCGCGATCTGTTTAATCGCCGC
CATTTTCCTTTTGTTCTGTTTGTTGCCGCCATCTGGACCTGCCAGGTGATCCCCATGTTTGCCATTTACACCTTTGGCCC
GCAAATCGTTGGTTTGTTGGGATTGGGGGTTGGCAAAAACGCGGCACTGGGGAACGTGGTGATTAGCCTGTTCTTTATGC
TCGGCTGTATTCCGCCGATGCTGTGGCTAAACACTGCCGGACGGCGTCCATTGTTGATTGGCAGCTTTGCCATGATGACG
CTGGCGCTGGCGGTTTTGGGGCTGATCCCGGATATGGGGATCTGGCTGGTAGTGATGGCCTTTGCGGTGTATGCCTTTTT
CTCTGGCGGGCCGGGTAATTTGCAGTGGCTCTATCCTAATGAACTCTTCCCGACGGATATCCGCGCCTCTGCCGTGGGCG
TGATTATGTCCTTAAGCCGTATTGGCACTATTGTATCGACCTGGGCACTGCCGATCTTTATCAATAATTACGGTATCAGT
AACACGATGCTAATGGGGGCGGGTATCTCGCTATTTGGCTTGTTGATTTCCGTAGCGTTTGCCCCGGAGACTCGAGGGAT
GTCACTGGCGCAGACCAGCAATATGACGATCCGCGGGCAGAGAATGGGGTAA

Upstream 100 bases:

>100_bases
TACCCGCGCGGCACCTTTGGTGTGGAGTTCCGTTACGGCTGATGTTGGTTTGATACGTAATGCCGTACTGACTCTCATTG
CAAAAAAACAGGAATAACCC

Downstream 100 bases:

>100_bases
TTTGTTCAGATTTCTCTCTTTTCTGAATCAATATTATTGACTATAAGCTGCGTGAATATATGACTACACTTTGTGGGAAA
ACAAAGGCGTAATCACGCGG

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKV
GRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFEEEQPQQTRFRDLFNRR
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMT
LALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGIS
NTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG

Sequences:

>Translated_443_residues
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKV
GRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFEEEQPQQTRFRDLFNRR
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMT
LALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGIS
NTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG
>Mature_443_residues
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKV
GRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFEEEQPQQTRFRDLFNRR
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMT
LALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGIS
NTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24497497, Length=380, Percent_Identity=27.3684210526316, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI90669191, Length=380, Percent_Identity=27.3684210526316, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI24308167, Length=439, Percent_Identity=22.7790432801822, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI31542327, Length=437, Percent_Identity=24.7139588100687, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI24497490, Length=391, Percent_Identity=25.8312020460358, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI166064021, Length=382, Percent_Identity=24.6073298429319, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4507005, Length=409, Percent_Identity=23.960880195599, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI302148518, Length=425, Percent_Identity=23.2941176470588, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI166197673, Length=366, Percent_Identity=24.8633879781421, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4506999, Length=439, Percent_Identity=24.1457858769932, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI203098995, Length=222, Percent_Identity=27.9279279279279, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI21553331, Length=313, Percent_Identity=22.0447284345048, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI216548223, Length=166, Percent_Identity=29.5180722891566, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI7662270, Length=192, Percent_Identity=25.5208333333333, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI73695465, Length=188, Percent_Identity=28.7234042553192, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI23510410, Length=189, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI47933389, Length=458, Percent_Identity=23.7991266375546, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI47933387, Length=458, Percent_Identity=23.7991266375546, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1786229, Length=443, Percent_Identity=99.7742663656885, Blast_Score=884, Evalue=0.0,
Organism=Escherichia coli, GI87082159, Length=431, Percent_Identity=34.338747099768, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789312, Length=401, Percent_Identity=25.6857855361596, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789207, Length=401, Percent_Identity=25.1870324189526, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790463, Length=424, Percent_Identity=24.0566037735849, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788074, Length=430, Percent_Identity=24.4186046511628, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788068, Length=464, Percent_Identity=24.7844827586207, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17565976, Length=332, Percent_Identity=26.2048192771084, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71986689, Length=429, Percent_Identity=24.4755244755245, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565978, Length=332, Percent_Identity=23.7951807228916, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193202825, Length=429, Percent_Identity=24.4755244755245, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32564663, Length=407, Percent_Identity=22.3587223587224, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71980582, Length=372, Percent_Identity=24.4623655913978, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71980584, Length=372, Percent_Identity=24.4623655913978, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17543784, Length=405, Percent_Identity=26.4197530864197, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193209824, Length=156, Percent_Identity=32.0512820512821, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71986504, Length=422, Percent_Identity=23.696682464455, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI212645980, Length=377, Percent_Identity=26.790450928382, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323512, Length=408, Percent_Identity=23.7745098039216, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321068, Length=429, Percent_Identity=22.1445221445221, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319718, Length=345, Percent_Identity=24.0579710144928, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28573193, Length=368, Percent_Identity=26.3586956521739, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644782, Length=368, Percent_Identity=26.3586956521739, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644778, Length=450, Percent_Identity=24, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24668456, Length=393, Percent_Identity=21.882951653944, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221330907, Length=350, Percent_Identity=24.8571428571429, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24652795, Length=411, Percent_Identity=23.6009732360097, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24668440, Length=399, Percent_Identity=23.5588972431078, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24649616, Length=355, Percent_Identity=24.2253521126761, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19922616, Length=389, Percent_Identity=24.6786632390745, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24652793, Length=411, Percent_Identity=23.6009732360097, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24649618, Length=355, Percent_Identity=22.5352112676056, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221457681, Length=431, Percent_Identity=23.8979118329466, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24658792, Length=393, Percent_Identity=23.9185750636132, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640198, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640196, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640200, Length=202, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161078612, Length=436, Percent_Identity=22.7064220183486, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 48682; Mature: 48682

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGA
CCCCCCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHH
GTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHH
IPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFEEEQPQQTRFRDLFNRR
HHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPM
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPN
HHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
ELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGISNTMLMGAGISLFGLLISVAF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCHHHHHHHHHHHC
APETRGMSLAQTSNMTIRGQRMG
CCCCCCCEEEECCCCEEEECCCC
>Mature Secondary Structure
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGA
CCCCCCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHH
GTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHH
IPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFEEEQPQQTRFRDLFNRR
HHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPM
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPN
HHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
ELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGISNTMLMGAGISLFGLLISVAF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCHHHHHHHHHHHC
APETRGMSLAQTSNMTIRGQRMG
CCCCCCCEEEECCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]