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The map label for this gene is hofQ [H]

Identifier: 218550647

GI number: 218550647

Start: 3413872

End: 3415152

Strand: Reverse

Name: hofQ [H]

Synonym: EFER_3357

Alternate gene names: 218550647

Gene position: 3415152-3413872 (Counterclockwise)

Preceding gene: 218550648

Following gene: 218550646

Centisome position: 74.43

GC content: 50.82

Gene sequence:

>1281_bases
GTGAGCCGGACCAATGGCAGTGGCAAAGGCAAGGAGAAGAAAATGAAGCAATGGATAGCCGCAATACTGATGATGGCTCT
TCCCGTCGCGCAGGCCGCGAAACCCGCAAAAGTGACGTTAGTGGTGGATGATGCACCTGTCGCACAGGTGTTACAGGCAC
TGGCAGAACAAGAGCGTCAGAATATCGTGGTTTCGCCGGATGTTAGTGGTCTCGTCTCTTTGCATTTGATCGATGTTCCC
TGGAAGCAGGCGTTGCAGACAGTGGTAAAAAGTGCCGGGCTGGTTTCGCGCCAGGAAGGTAATATTTTGCATATACACTC
TGCTGCCTGGCAAAACGAAAATGCAGCACGACAAGAAGCTGAACAGGTCCGGCGCCTGGCCAGTTTACCTGTAGAGCATC
GCGCAATTGCTCTGCAATATGCGGATGCTGCTGAGCTGGCAAAAGCGGGCGGGAAACTATTGAGCGCCAAAGGCAGTATG
ACGGTTGATACTCGCACCAATCGCCTTTTATTGCGTGACAATAAAACCGCTTTAGCCGCTCTGGAACACTGGATCTCAGA
AATGGATGTGCCCGTAGGGCAGGTTGAACTGGCTGCGCATATTGTGACTATCAATGAAAAAAGCCTGCGTGAGTTGGGCG
TGAAATGGACGGCTGGCGAGGCACAACAAGCCGGTAAGGTGGGGCAGGTGACTACCCTGAGCAGCGATCTGGCAGTCGCA
ACCGCTACAACCCAGGTGGGCTTTAACATTGGACGCATAAATGGGCGTTTACTGGATCTTGAACTCTCTGCTCTGGAGCA
GAAACAGCAACTGGATATTATTGCCAGTCCACGCTTACTGGCATCGCACTTACAACCAGCCAGTATTAAGCAGGGCAGCG
AAATACCTTATCAGGTTTCCAGTGGTGAGAGTGGCGCGACATCAGTAGAGTTTAAAGAGGCGGTGTTAGGTATGGAAGTC
ACACCAACGGTATTACAACAAGGACGAATTCGTTTAAAGCTGCATATCAGCCAGAATGTGCCAGGGCAGGTGCTACAACA
ATCTGATGGCGAAGTGTTGACCATCGATAAACAAGAGATCGAAACGCAGGTAGAGGTCAAAAGCGGGGAGACCCTGGCTC
TGGGCGGCATATTTTCGCGCAAAAATAAAACGGGTAAGGATAGCATTCCACTCTTAGGTGATATTCCGTGGCTTGGGCAA
TTATTCAGTCATGATGGAAAAGAAAATGAACGTCGTGAACTGGTCGTGTTTATCACGCCCAGACTGGTCTCCAGCGAGTA
A

Upstream 100 bases:

>100_bases
CATAAGTGGCAGCGCGTGGAACAGCGAGATGTGTTGGAAAACGGCTGGACGATTTTACAGATAACCCCTGAGTTTCTGAC
CCTTAATACCGGCAAAACAT

Downstream 100 bases:

>100_bases
CTCGTGCATAAACACGAGATGTTTTTTGCGCTGAACACGTTTCAGGGATTTGACGCGCGAAGGTATTTAGCATACAAGGA
GTACCGATTTGAGAGTCGGT

Product: outer membrane porin HofQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSRTNGSGKGKEKKMKQWIAAILMMALPVAQAAKPAKVTLVVDDAPVAQVLQALAEQERQNIVVSPDVSGLVSLHLIDVP
WKQALQTVVKSAGLVSRQEGNILHIHSAAWQNENAARQEAEQVRRLASLPVEHRAIALQYADAAELAKAGGKLLSAKGSM
TVDTRTNRLLLRDNKTALAALEHWISEMDVPVGQVELAAHIVTINEKSLRELGVKWTAGEAQQAGKVGQVTTLSSDLAVA
TATTQVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEV
TPTVLQQGRIRLKLHISQNVPGQVLQQSDGEVLTIDKQEIETQVEVKSGETLALGGIFSRKNKTGKDSIPLLGDIPWLGQ
LFSHDGKENERRELVVFITPRLVSSE

Sequences:

>Translated_426_residues
MSRTNGSGKGKEKKMKQWIAAILMMALPVAQAAKPAKVTLVVDDAPVAQVLQALAEQERQNIVVSPDVSGLVSLHLIDVP
WKQALQTVVKSAGLVSRQEGNILHIHSAAWQNENAARQEAEQVRRLASLPVEHRAIALQYADAAELAKAGGKLLSAKGSM
TVDTRTNRLLLRDNKTALAALEHWISEMDVPVGQVELAAHIVTINEKSLRELGVKWTAGEAQQAGKVGQVTTLSSDLAVA
TATTQVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEV
TPTVLQQGRIRLKLHISQNVPGQVLQQSDGEVLTIDKQEIETQVEVKSGETLALGGIFSRKNKTGKDSIPLLGDIPWLGQ
LFSHDGKENERRELVVFITPRLVSSE
>Mature_425_residues
SRTNGSGKGKEKKMKQWIAAILMMALPVAQAAKPAKVTLVVDDAPVAQVLQALAEQERQNIVVSPDVSGLVSLHLIDVPW
KQALQTVVKSAGLVSRQEGNILHIHSAAWQNENAARQEAEQVRRLASLPVEHRAIALQYADAAELAKAGGKLLSAKGSMT
VDTRTNRLLLRDNKTALAALEHWISEMDVPVGQVELAAHIVTINEKSLRELGVKWTAGEAQQAGKVGQVTTLSSDLAVAT
ATTQVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEVT
PTVLQQGRIRLKLHISQNVPGQVLQQSDGEVLTIDKQEIETQVEVKSGETLALGGIFSRKNKTGKDSIPLLGDIPWLGQL
FSHDGKENERRELVVFITPRLVSSE

Specific function: Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=412, Percent_Identity=86.1650485436893, Blast_Score=722, Evalue=0.0,
Organism=Escherichia coli, GI87082242, Length=346, Percent_Identity=27.7456647398844, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR001814 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 46037; Mature: 45906

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTNGSGKGKEKKMKQWIAAILMMALPVAQAAKPAKVTLVVDDAPVAQVLQALAEQERQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHC
NIVVSPDVSGLVSLHLIDVPWKQALQTVVKSAGLVSRQEGNILHIHSAAWQNENAARQEA
CEEECCCCCCEEEEEEEECCHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCCHHHHHH
EQVRRLASLPVEHRAIALQYADAAELAKAGGKLLSAKGSMTVDTRTNRLLLRDNKTALAA
HHHHHHHHCCCCHHEEEEEECCHHHHHHCCCCEEECCCCEEEECCCCEEEEECCCHHHHH
LEHWISEMDVPVGQVELAAHIVTINEKSLRELGVKWTAGEAQQAGKVGQVTTLSSDLAVA
HHHHHHHHCCCCCCEEEEEEEEEECHHHHHHCCCEECCCCHHHCCCCCEEEEECCCCEEE
TATTQVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVS
EEEHHHCCEEEECCCEEEEEEHHHHHHHHHCCEECCCHHHHHCCCCCCCCCCCCCCEEEC
SGESGATSVEFKEAVLGMEVTPTVLQQGRIRLKLHISQNVPGQVLQQSDGEVLTIDKQEI
CCCCCCCCHHHHHHHHCCCCCHHHHHCCCEEEEEEECCCCCHHHHHCCCCCEEEEEHHHC
ETQVEVKSGETLALGGIFSRKNKTGKDSIPLLGDIPWLGQLFSHDGKENERRELVVFITP
CEEEEECCCCEEEECCEECCCCCCCCCCCCCEECCHHHHHHHCCCCCCCCCCEEEEEECC
RLVSSE
CCCCCC
>Mature Secondary Structure 
SRTNGSGKGKEKKMKQWIAAILMMALPVAQAAKPAKVTLVVDDAPVAQVLQALAEQERQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHC
NIVVSPDVSGLVSLHLIDVPWKQALQTVVKSAGLVSRQEGNILHIHSAAWQNENAARQEA
CEEECCCCCCEEEEEEEECCHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCCHHHHHH
EQVRRLASLPVEHRAIALQYADAAELAKAGGKLLSAKGSMTVDTRTNRLLLRDNKTALAA
HHHHHHHHCCCCHHEEEEEECCHHHHHHCCCCEEECCCCEEEECCCCEEEEECCCHHHHH
LEHWISEMDVPVGQVELAAHIVTINEKSLRELGVKWTAGEAQQAGKVGQVTTLSSDLAVA
HHHHHHHHCCCCCCEEEEEEEEEECHHHHHHCCCEECCCCHHHCCCCCEEEEECCCCEEE
TATTQVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVS
EEEHHHCCEEEECCCEEEEEEHHHHHHHHHCCEECCCHHHHHCCCCCCCCCCCCCCEEEC
SGESGATSVEFKEAVLGMEVTPTVLQQGRIRLKLHISQNVPGQVLQQSDGEVLTIDKQEI
CCCCCCCCHHHHHHHHCCCCCHHHHHCCCEEEEEEECCCCCHHHHHCCCCCEEEEEHHHC
ETQVEVKSGETLALGGIFSRKNKTGKDSIPLLGDIPWLGQLFSHDGKENERRELVVFITP
CEEEEECCCCEEEECCEECCCCCCCCCCCCCEECCHHHHHHHCCCCCCCCCCEEEEEECC
RLVSSE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1309529; 9278503; 7901733 [H]